Medicinal chemistry is a broad discipline encompassing the design, identification, synthesis and development of chemicals in drug discovery. It includes a number of techniques covering structural biology, synthetic chemistry and molecular biology. Technologies used in medicinal chemistry include ADME, lab-on-a-chip, high content screening and assay assembly.
HistologiX is a leading GLP/GCP accredited Contract Research Organisation based in the UK specialising in Histology, Immunohistochemistry (IHC) and Digital Pathology services. HistologiX works with a broad range of clients from big pharma to small and medium biotech companies worldwide. Our team of scientists have in excess of 120 years combined experience and a customer retention rate of 80%.
Charles River is a preclinical drug discovery CRO that manages your project from drug target discovery to hit identification, hit-to-lead, and lead optimization
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NanoXact Silica Nanospheres - 10 mg/mL or 5 mg/mL in water, Sizes 20 nm - 1000 nm
NanoXact Silica Nanospheres - Dried Powder, Sizes 80 nm - 1000 nm
BioPure Gold Nanospheres - Bare (Citrate) - 1 mg/mL in water, Sizes 5 nm - 100 nm
Polyview® provides a flexible and comprehensive search engine to retrieve data that is stored across synthesis and screening activities. The user can view combinations of data from multi-step synthetic and analytical processes, collected through the lifetime of the test sample. Querying Find samples based on any logical combination of experiment values saved to the database. Search the entire database or restrict your se…
Spectra Studio™ is designed to save users time by providing a number of clustering algorithms to automatically group similar spectra. Visualization and manipulation tools allow users to review the clustering results, manually manipulate group assignments and save the results for later retrieval and comparison with other experimental data. Automated Clustering Load spectra spanning multiple experiments and multiple librar…
Design, implement, and characterize formulations using the automated Adhesives, Coatings and Sealants Workflow Rapidly and precisely formulate libraries, measure and adjust viscosity, prepare thin coatings on various substrates, and measure their properties. The Adhesives, Coatings and Sealants Workflow utilizes multiple Core Modules equipped with liquid handling, heating/stirring, viscometric indexing, and a drawdown tool to…
Offered in a number of customized configurations, the Symyx Home and Personal Care workflow allows you to formulate, apply, and test materials more quickly than ever before. By combining Symyx hardware and software capabilities, this workflow enables you to develop and optimize new formulations, apply formulations to various substrates, and rigorously evaluate these applications using a wide variety of testing conditions. Pre…
Perform 48–96 meaningful slurry or solution phase (co)polymerizations per day and increase the productive value of research and development by enabling better decisions, faster. Through the integration of reactor hardware, robotics, and custom software capabilities, the Plastics Workflow facilitates 48–96 slurry or solution-phase batch reactor polymerizations with full computer control and in situ temperature and pressure moni…
Create formulations for stability and compatibility tests. Generate and test hundreds of complex liquid formulations at a time using the automated Liquid Formulations Workflow. Use visual, chromatographic, or spectroscopic tools to monitor the stability of the libraries of samples. It is also available in a Benchtop Systems configuration. The Benchtop System is a self-contained, software-driven system, while the integrated wor…
Waters offers PoraPak™ Rxn, a family of polymer-based chromatography products for superior cleanup of synthetic reactions. PoraPak Rxn products are available in two chemistries: PoraPak Rxn CX, a strong cation-exchange sorbent and PoraPak Rxn RP, a reversed-phase sorbent.PoraPak Rxn sorbents are based on copolymers that exhibit the following properties:Hard material that does not develop increasing back pressure with flowLitt…
STN is an online database service that provides global access to published research, journal literature, patents, structures, sequences, properties, and other data.
Virtual tissues services for biomedical research features high fidelity tissue simulation and modelling to grow virtual tissue from a single cell, giving unprecedented insight into lineage commitment phenomena of stem cells with insight into signalling pathways and detailed gene regulatory networks.With Endogenics complementing traditional techniques, researchers can simulate human cell development and tissue organization and…
The EXPRESS-Pick small molecule screening compound stock is a collection of 460,000 druglike, small molecule compounds, available for custom selection.
Structurally diverse small molecule libraries with broad 3D pharmacophore coverage for hit identification ChemBridge offers two, complementary DIVERSet™ Libraries, each composed of 50,000 leadlike and druglike compounds. Both DIVERSet Libraries (the DIVERSet-EXP and the DIVERSet-CL) are designed to provide the greatest coverage of pharmacophore space within 50,000 compounds while maintaining chemical structure diversity. Th…
CNS-directed selection from ChemBridge's EXPRESS-Pick Collection screening compound stock.
Pre-plated selection from ChemBridge's EXPRESS-Pick Collection screening compound stock.
Ion channel-directed selection from ChemBridge's EXPRESS-Pick Collection screening compound stock.
GPCR-targeted compounds based on beta-turn mimetic scaffolds designed by ChemBridge.
Kinase-directed selection from ChemBridge's EXPRESS-Pick Collection screening compound stock.
Kinase-directed selection from ChemBridge's CORE Library screening compound stock.
QSARpro software is designed for identifying the relationship activity with structural parameters and its analysis. What QSARpro offers:• It evaluates more than 1000 molecular descriptors* • It offers not only 2D QSAR, 3D QSAR and GQSAR but also comes with all advanced molecular operations from the VLife Engine • For medicinal chemist, QSARpro offers seamless integration to AutoQSAR*This includes: physicochemical, topological…
