High-Content Screening Products & Reviews

25

High-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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µ-Slide Angiogenesis

ibidi GmbH

Use this slide to investigate angiogenesis in tube formation assays. Also ideal for 3D cell culture and immunofluorescence staining. Also available in a 96 well format.

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Pala Single Cell Dispenser

Bio-Techne

The Namocell Pala Single Cell Dispenser makes single cell isolation and sorting effortless. It has 2 lasers and up to 11 fluorescent channels and can isolate virtually every cell type. Pala offers 3 sorting modes for versatile cell isolation needs: Single Cell Dispensing, Rare Cell Enrichment and Bulk Cell Sorting. This benchtop instrument simplifies and empowers many single cell applications and requires no special training…

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Assay development and screening

Selvita

Selvita provides its clients with effective drug discovery support based on broad capabilities and deep expertise in small molecule drug discovery. The in vitro pharmacology support offering at Selvita covers drug discovery phases from target validation through to preclinical candidate selection. We provide a versatile protein-to-cell approach for the development of pharmacologically active compounds and biologics.

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Thermo Scientific Neurite Outgrowth Reagent Kit

The Neurite Outgrowth HCS Reagent Kit product provides a more effective solution for quantifying neurite outgrowth by combining high-content screening (HCS)-quality fluorescence reagents with a validated, automation-compatible protocol. Neurite Outgrowth Reagent Kit Features: Neuronal-specific fluorescent reagent identifies neuronal cell bodies and neurites in a heterogeneous cell population without isolation steps Val…

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Thermo Scientific Synaptogenesis Kit

The Synaptogenesis Kit enables simultaneous detection of neuronal population, neurite, pre-synaptic vesicle, post-synaptic puncta and synapse using a fixed end-point assay based on immunofluorescence detection in cells grown on standard high-density microplates.

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COPAS™ Large Particle Flow Cytometers

Union Biometrica, Inc.

COPAS instruments provide flow cytometry for objects that are too large for traditional cytometers and offer an alternative to manual sorting (under a microscope). These systems sort and dispense objects based on size and fluorescent parameters. Automating this process offers increased speed, sensitivity, quantification, and repeatability of experiments.

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BioSorter® Large Particle Flow Cytometer

Union Biometrica, Inc.

The BioSorter is a large particle flow cytometer designed to analyze, sort and dispense biological materials and other objects ranging in size from 10 to 1500 microns in diameter. The system is designed to handle objects which are too large or too fragile for traditional flow cytometers. Examples include small multicellular model organisms, delicate large cells / cell clusters, small seeds and beads used as microcarriers or fo…

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