High-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
The CHEMICON® In Vitro Vascular Permeability Assay is performed in a 24-well tissue culture plate with 12 cell culture inserts. The inserts contain 1.0 μm symmetrical pores within a transparent polyethylene membrane. The high pore density membranes permit amplified rates of basolateral diffusion with molecules of interest for permeability assays. The membrane is tissue culture treated on both sides for cell growth. Within CHE…
Live cell tracking of single cell or cell population migrationEstablishes a stable and linear concentration gradient that lasts ≥ 48 hoursHelps distinguish chemotaxis from random movementAllows for multiparametric analysis, including cell directionality and velocityEnhanced optical imaging of slow- and fast-migrating cellsAnalyze 3 chemoattractants in parallel for increased throughput and flexibilityNo need to spend time or mo…
The Millicell μ-Angiogenesis activation and inhibition kits provide a powerful, quantitative platform for real-time monitoring of changes in tubule formation with unprecedented optical resolution.Continuous, live monitoring of cells as tubules formEven, flat slide surface prevents any liquid meniscus from forming, eliminating out-of-focus areasFull well visualization at low magnificationOptimized assay conditions in a miniatur…
A Complete Solution for Functional Live Cell Assays Under Controlled Shear Flow—Great for Labs With an Existing Inverted Microscope
Cell Health Profiling V2 is a flexible image analysis application employing advanced cell-level logic to detect and classify cell health-related events. It analyzes patterns of cellular fluorescent labeling that can be used to classify cells as undergoing apoptotic, necrotic, or other cell death mechanisms. This application has been biologically validated, enhancing confidence in your image-based data. Available for the Cel…
The Cell Cycle V2 BioApplication is a sophisticated image analysis algorithm that performs automated analysis of the cell cycle phase of individual and populations of cells. It reports cell cycle phase as well as the state of up to 3 target proteins for every cell analyzed, and correlates the target data with DNA content. This application has been biologically validated, enhancing confidence in your image-based data. Availa…
Optimized for brewing yeast, wine yeast and other small cells with one channel of fluorescence.
The most robust and versatile HCA platform available.
High-throughput single-cell analysis system: analyze hundreds of genes across tens of thousands of single cells in parallel
A module for the WOLF ® G2 Cell Sorter to sort and dispense into 96- or 384-well plates.
Use this slide to investigate angiogenesis in tube formation assays. Also ideal for 3D cell culture and immunofluorescence staining. Also available in a 96 well format.
Charles River is a preclinical drug discovery CRO that manages your project from drug target discovery to hit identification, hit-to-lead, and lead optimization
The NovoCyte Penteon flow cytometer builds on its successful predecessor, the NovoCyte, and provides an expanded set of capabilities that accommodate today’s high-end and increasingly sophisticated multi-color flow cytometry assays. You now have the flexibility to choose from up to 30 fluorescence channels utilizing up to 5 lasers with up to 30 independent detectors. The NovoSampler Q can be integrated into different laborator…
The Namocell Pala Single Cell Dispenser makes single cell isolation and sorting effortless. It has 2 lasers and up to 11 fluorescent channels and can isolate virtually every cell type. Pala offers 3 sorting modes for versatile cell isolation needs: Single Cell Dispensing, Rare Cell Enrichment and Bulk Cell Sorting. This benchtop instrument simplifies and empowers many single cell applications and requires no special training…
Our flow cytometry service offers a range of assays to support pre-clinical through to late phase drug development.
Excite your probes at any wavelengths to validate their NIR-II emissions with Photon etc's ClaIR infrared microplate reader.
A module for the WOLF ® G2 Cell Sorter to provide cooling and stirring of sample.
Ariadne Software®, a brand of BioData Solutions®, offers automation software for bioanalytical auditing of small and large molecule pharmacokinetic data as well as cut point and sensitivity determination for ADA data.
First IHC companion diagnostic for determining folate receptor alpha (FOLR1) protein expression in EOC patients who may benefit from ELAHERE™ (mirvetuximab soravtansine)
Selvita provides its clients with effective drug discovery support based on broad capabilities and deep expertise in small molecule drug discovery. The in vitro pharmacology support offering at Selvita covers drug discovery phases from target validation through to preclinical candidate selection. We provide a versatile protein-to-cell approach for the development of pharmacologically active compounds and biologics.
Label-free, high-content live cell imaging and anaylsis: a complete solution for non-invasive, long-term assessment of single cells to 96 wells
Quantify effector to target cell binding, phenotypic changes, and killing, all in a single label-free assay.
