ADME-Toxicology Products & Reviews
ADME-toxicology (ADME-Tox) studies are used in pharmacology and pharmacokinetics to assess the activity/toxicity of drugs <i>in vivo</i> or <i>in vitro</i>. Find bioassays for absorption, distribution, metabolism, and excretion of drug molecules including cytotoxicity, transporter/permeability, metabolism and activity assays as well as hepatocytes and cell lines for ADME. Find the best ADME-toxicology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
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PI Staining Solution for Apoptosis
Membrane-exclusion, DNA binding dye to detect dead and/or necrotic cells
ViaStain Live Caspase 3/7 Detection for 2D/3D Culture
Real-time measurement of apoptosis in 2D culture and 3D tumor spheroids
ViaStain Live Caspase 3/7 Detection for 2D/3D Culture with Hoechst
Real-time measurement of apoptosis in 2D culture and 3D tumor spheroids, with Hoechst to determine total number of cells
CaspGLOW Fluorescein in Active Caspase-3 Staining Kit
Fluorescein active Caspase-3 staining kit for apoptosis
CaspGLOW Fluorescein in Active Caspase-3 Staining Kit
Fluorescein active Caspase-3 staining kit for apoptosis
CaspGLOW Fluorescein in Active Caspase-8 Staining Kit
Fluorescein active Caspase-8 staining kit for apoptosis
CaspGLOW Fluorescein in Active Caspase-8 Staining Kit
Fluorescein active Caspase-8 staining kit for apoptosis
ViaStain CFSE
Green cell proliferation dye; daughter cells receive half of the present dye from the parent cell
Invitrogen™ ReadyProbes™ Cell Viability Imaging Kit, Blue/Green
Thermo Fisher ScientificRoom temperature-stable, ready-to-use cell viability assay
Invitrogen™ ReadyProbes™ Cell Viability Imaging Kit, Blue/Red
Thermo Fisher ScientificRoom temperature-stable, ready-to-use cell viability assay
Invitrogen™ eBioscience™ JC-1 Mitochondrial Membrane Potential Dye
Thermo Fisher ScientificJC-1 is a membrane permeable dye widely used for determining mitochondrial membrane potential in flow cytometry and fluorescent microscopy. This dye can selectively enter the mitochondria where it reversibly changes coloras membrane potentials increase (over values of about 80-100 mV). When excited at 488 nm, the emission shift goes from 530 nm (monomeric JC-1) to 590 nm (aggregate JC-1), which are easily detected using filter…
Invitrogen™ CellEvent™ Caspase 3/7 Green Ready Flow™ Reagent
Thermo Fisher ScientificCellEvent Caspase-3/7 Green Ready Flow Reagent enables the flow cytometric detection of activated caspase-3 and caspase-7 in apoptotic cells. The product includes 2 reagents: the novel fluorogenic substrate CellEvent Caspase-3/7 Green Detection Reagent and SYTOX™ AADvanced™ Dead Cell Stain.FeaturesStable at room temperatureConvenient, ready-to-use format—no need to dilute, weigh, or pipetteExceptionally bright green fluorescen…
Invitrogen™ Click-iT™ EdU Alexa Fluor™ 647 Flow Cytometry Assay Kit
Thermo Fisher ScientificThe Click-iT EdU Alexa Fluor 647 Flow Cytometry Assay Kit provides a simplified, more robust assay for analyzing DNA replication in proliferating cells as compared to traditional BrdU methods. The Click-iT EdU Flow Cytometry Assay Kits rely on EdU (5-ethynyl-2´-deoxyuridine), a thymidine analog which is incorporated into DNA during active DNA synthesis, which is then detected using click chemistry, a copper catalyzed covalent…
Invitrogen™ Click-iT™ EdU Alexa Fluor™ 488 Flow Cytometry Assay Kit
Thermo Fisher ScientificThe Click-iT EdU Alexa Fluor 488 Flow Cytometry Assay Kit provides a simplified, more robust assay for analyzing DNA replication in proliferating cells as compared to traditional BrdU methods. The Click-iT EdU Flow Cytometry Assay Kits rely on EdU (5-ethynyl-2´-deoxyuridine), a thymidine analog which is incorporated into DNA during active DNA synthesis, which is then detected using click chemistry, a copper catalyzed covalent…
Invitrogen™ Click-iT™ Plus EdU Pacific Blue Flow Cytometry Assay Kit
Thermo Fisher ScientificThe Click-iT Plus EdU Pacific Blue Flow Cytometry Assay Kit provides a simplified, more robust assay for analyzing DNA replication in proliferating cells as compared to traditional BrdU methods. The Click-iT EdU Flow Cytometry Assay Kits rely on EdU (5-ethynyl-2´-deoxyuridine), a thymidine analog which is incorporated into DNA during active DNA synthesis, which is then detected using click chemistry, a copper catalyzed covalen…
Invitrogen™ Click-iT™ Plus EdU Alexa Fluor™ 350 Flow Cytometry Assay Kit
Thermo Fisher ScientificThe Click-iT Plus EdU Alexa Fluor 350 Flow Cytometry Assay Kit provides a simplified, more robust assay for analyzing DNA replication in proliferating cells as compared to traditional BrdU methods. The Click-iT EdU Flow Cytometry Assay Kits rely on EdU (5-ethynyl-2´-deoxyuridine), a thymidine analog which is incorporated into DNA during active DNA synthesis, which is then detected using click chemistry, a copper catalyzed cova…
Invitrogen™ Click-iT™ Plus EdU Alexa Fluor™ 594 Flow Cytometry Assay Kit
Thermo Fisher ScientificThe Click-iT Plus EdU Alexa Fluor 594 Flow Cytometry Assay Kit provides a simplified, more robust assay for analyzing DNA replication in proliferating cells as compared to traditional BrdU methods. The Click-iT EdU Flow Cytometry Assay Kits rely on EdU (5-ethynyl-2´-deoxyuridine), a thymidine analog which is incorporated into DNA during active DNA synthesis, which is then detected using click chemistry, a copper catalyzed cova…
Invitrogen™ CellTrace™ CFSE Cell Proliferation Kit
Thermo Fisher ScientificCellTrace CFSE Cell Proliferation Kit is used for in vitro and in vivo labeling of cells to trace multiple generations using dye dilution by flow cytometry. Dye dilution analysis requires extremely bright fluorescent dyes, which is supplied by the Cell Trace CFSE dye. Using this dye, eight or more generations can be visualized. The reliable and homogeneous staining among cells in the population allows for visualization of dist…