Next Generation Sequencing Products & Reviews

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Next-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Shotgun metagenomics sequencing

Novogene

Shotgun metagenomic sequencing is designated to sequence the total genomic DNA from environmental samples without the prior isolation and cultivation of individual species. The services are applied for studying the rich genetic repertoire of microbial communities with taxonomy information, and for studying system evolution, gene function, and metabolic network of environmental microorganisms.

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Epigenome sequencing

Novogene

Novogene provides Whole Genome Bisulfite Sequencing (WGBS), Reduced Representation Bisulfite Sequencing (RRBS), Chromatin Immunoprecipitation Sequencing (ChIP-seq), RNA Immunoprecipitation Sequencing (RIP-seq), and Assay for Transposase-Accessible Chromatin Sequencing (ATAC-seq), tailored for both bulk and single-cell samples.

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Shasta™ Single Cell System

Takara Bio

The Shasta Single Cell System is a state-of-the-art, automated dispensing and imaging platform for single-cell biomarker discovery, surpassing the boundaries of existing methods. and enabling the detection of more biomarkers—splicing isoforms, gene fusions, and CNVs—in more cells than ever before.

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  • Life Sciences Product of the Year Award



DeNovox Automated De Novo Sequencing Software

Thermo Fisher Scientific

DeNovoX software automates and accelerates sequencing, returning results equal to or better than those formerly achieved through expert manual sequencing of peptides within proteins and is ideally suited for high-throughput analyses of peptide mixtures. Product detail: DeNovoX is a fully-automated de novo sequencing software program that is capable of determining complete or partial amino acid sequences of unknown peptide…

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SeqSolve Integromics

Integromics

SeqSolve™ is an advanced and user-friendly software solution for the tertiary analysis of Next Generation Sequencing (NGS) data. By integrating state-of-the-art bioinformatics methods into one-click analysis workflows, SeqSolve is the only software able to provide scientists with such a combination of both cutting edge and intuitive user experience. Its Click And Go® technology enables the automatic processing of the data, whi…

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SeqCap EZ Human Exome Library v3.0

Discover More, Sequence Less Built upon the NimbleGen Sequence Capture empirically optimized probe design algorithm with high efficiency uniformity of capture1, and now with expanded coverage of coding exons, SeqCap EZ Exome v3.0 offers increased performance. Capture the most comprehensive picture of the human exome with SeqCap EZ Exome Library v3.0. Based on the latest database builds and offering a 64Mb sequence capture, Seq…

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PGN003 PureGenome™ Next Generation Sequencing Library Amplifier

Merck

The PureGenome™ High Efficiency Next Generation Sequencing (NGS) Library Preparation Reagents are uniquely optimized as a one-stop solution for NGS Library Preparation. Validated for sequencing compatibility with Illumina® instruments; three sets of reagents are offered each having a unique functionality in the library preparation work flow. The PureGenome NGS Library DNA Modifier, when purchased with the PureGenome NGS Librar…

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PGN002 PureGenome™ Next Generation Sequencing Library A-Tail Enhancer

Merck

The PureGenome™ High Efficiency Next Generation Sequencing (NGS) Library Preparation Reagents are uniquely optimized as a one-stop solution for NGS Library Preparation. Validated for sequencing compatibility with Illumina® instruments; three sets of reagents are offered each having a unique functionality in the library preparation work flow. The PureGenome NGS Library DNA Modifier, when purchased with the PureGenome NGS Librar…

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PGN001 PureGenome™ Next Generation Sequencing Library DNA Modifier

Merck

The PureGenome™ High Efficiency Next Generation Sequencing (NGS) Library Preparation Reagents are uniquely optimized as a one-stop solution for NGS Library Preparation. Validated for sequencing compatibility with Illumina® instruments; three sets of reagents are offered each having a unique functionality in the library preparation work flow. The PureGenome NGS Library DNA Modifier, when purchased with the PureGenome NGS Librar…

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PGN004 PureGenome™ Next Generation Sequencing Library Validator Kit

Merck

The quality of sequence obtained from Next Generation sequencing platforms such as Illumina, Inc. requires the accurate determination of input library DNA. Loading too much DNA can lead to overlapping clusters and loss of read counts whereas too little input can lead to poor read lengths and lower sequence output. The PureGenome™ NGS Library Validator Kit measures the absolute amount of adapter-ligated, sequence ready DNA in I…

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Pellet Paint® NF Co-precipitant

Merck

Pellet Paint® NF Co-Precipitant* is a non-fluorescent dye-labeled carrier compatible with fluorescent sequencing. It facilitates rapid removal of BigDye™ Terminators (PE Corp.) during the alcohol precipitation of cycle sequencing reaction products. Cycle sequencing reactions can be precipitated rapidly with centrifugation times of 10 minutes. The easily visualized carrier provides a simple confirmation that precipitation has o…

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Variant Analysis

Ingenuity Systems Inc.

Identify causal variants from human sequencing data in just hours Rapidly Identify and Prioritize Variants Ingenuity Variant Analysis combines analytical tools and integrated content to help you rapidly identify and prioritize variants by drilling down to a small, targeted subset of compelling variants based both upon published biological evidence and your own knowledge of disease biology. Biological Interpretation of your Var…

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NEBNext® DNA Library Prep Master Mix Set for 454™

New England Biolabs Inc.

The NEBNext® DNA Library Prep Master Mix Set for 454™ contains enzymes and buffers in convenient master mix formulations that are ideally suited for sample preparation for next-generation sequencing, and for preparation of single stranded DNA for use in high density hybridization arrays or for genomic subtraction hybridization methods. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation o…

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NEBNext® DNA Library Prep Set for SOLiD™

New England Biolabs Inc.

The NEBNext® DNA Library Prep Set for SOLiD™ contains enzymes and buffers in convenient master mix formulations that are ideally suited for sample preparation for next-generation sequencing and for preparation of expression libraries. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expression library cons…

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NEBNext® Fast DNA Fragmentation & Library Prep Set for Ion Torrent

New England Biolabs Inc.

The NEBNext Fast DNA Fragmentation & Library Prep Set for Ion Torrent contains enzymes and buffers in convenient master mix formulations that are ideally suited for sample preparation for next-generation sequencing on an Ion Torrent PGM™. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expression library…

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NEBNext® Fast DNA Library Prep Set for Ion Torrent™

New England Biolabs Inc.

The NEBNext® Fast DNA Library Prep Set for Ion Torrent™ contains enzymes and buffers in convenient master mix formulations that are ideally suited for sample preparation for next-generation sequencing on a Ion Torrent PGM™. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expression library construction. T…

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NEBNext® Quick DNA Library Prep Master Mix Set for 454™

New England Biolabs Inc.

The NEBNext Quick DNA Library Prep Master Mix Set for 454 contains enzymes and buffers in convenient master mix formulations that are ideally suited for sample preparation for next-generation sequencing, and for preparation of expression libraries. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expressio…

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NEBNext® dsDNA Fragmentase Reaction Buffer

New England Biolabs Inc.

New England Biolabs supplies a 10X reaction buffer with all of its enzymes. At a 1X concentration this reaction buffer assures optimal activity of the enzyme. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expression library construction.NEBNext® dsDNA Fragmentase Reaction Buffer Components: 20mM Tris…

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NEBNext® mRNA Library Prep Master Mix Set for 454™

New England Biolabs Inc.

The NEBNext mRNA Library Prep Master Mix Set for 454 contains enzymes and buffers that are ideally suited for sample preparation for next-generation sequencing, and for preparation of expression libraries. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expression library construction. The reagents includ…

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