Probes Products & Reviews

Dual-labelled probes featuring the original BHQ dye technologies

Compact PCR probes for detecting difficult target sequences

The QuantiFluor™ RNA System contains a fluorescent RNA-binding dye that enables sensitive quantitation of small amounts of RNA in solution. Detecting and quantitating small amounts of RNA is a very important step used in many biological applications, particularly in molecular biology techniques. These include measuring yields of in vitro transcribed RNA and measuring RNA concentrations before performing Northern blot anal…

Twist Custom Panels can be designed and built to cover a wide range of panel sizes, target regions, and multiplexing requirements — all with exceptional and consistent performance. Whether you design your own panel from scratch or add targets to enhance the content of existing panels, you can use your Twist Custom Panel with Twist’s modular library preparation kits or seamlessly integrate them into an existing workflow.

Twist Bioscience, the leader in synthetic DNA with unparalleled precision at scale, is redefining targeted sequencing performance with the Twist Human Core Exome Kit. This kit includes library preparation and enrichment components, allowing the flexibility to lower sequencing costs, increase sample throughput, and achieve a higher depth of coverage across target regions with uncompromising quality.

Exome sequencing has become a widely used practice in clinics and diagnostics. The superior performance of the Twist Human Core Exome provides the optimal solution for sequencing of protein coding genes, while focusing on the most accurate curated subset— CCDS database.

Agilent provides the most comprehensive menu of FISH probes for rapid identification of a wide range of chromosomal aberrations across the genome. Our catalog probes target relevant regions for a wide range of applications such as detection of aneuploidy, constitutional microdeletion syndromes, various rearrangements in oncology, and constitutional cytogenetics. Agilent's Comprehensive Menu of FISH Probes Provides: Coverage o…

A dual-labelled probe that combines a hairpin structure and a PCR primer element in a single oligo, allowing for target detection through a unimolecular mechanism. Mismatched hybrids are less stable than the reformed stem region. Therefore, Scorpions Primers only produce signal when the probe region hybridizes to a perfect-match target sequence within the primer extension product. 

As our latest generation of RNA library preparation kits, KAPA RNA HyperPrep Kits utilize a novel chemistry and combines enzymatic steps to achieve fewer reaction purifications and yield high-quality RNA-seq libraries in a single day. They also offer flexible workflow options that include the enrichment of desired transcripts by selective mRNA capture or rRNA depletion.

Efficient, and uniform hybridization-based capture for Whole Exome Sequencing Combining more than a decade of probe-design experience with an improved probe-manufacturing process, the new KAPA HyperExome probe pools enable efficient, uniform hybridization-based capture for Whole Exome Sequencing (WES).

KAPA HyperPETE (Primer Extension Target Enrichment) is a novel hybridization capture technology designed to employ primer extension reactions to specifically capture and release target library molecules for sequencing.

KAPA EvoPlus V2 Kits is an enhanced enzymatic DNA library preparation solution that features improved fragmentation performance, insensitivity to inhibitors, increased conversion efficiency & fewer sequencing artifacts.

Achieve high-performing NGS library preparation from mechanically fragmented DNA or cell-free DNA (cfDNA) in a streamlined, automation-friendly workflow with KAPA EvoPrep Kit. The KAPA EvoPrep workflow reduces pipetting and reagent preparation steps and is validated with challenging sample inputs such as cfDNA and FFPET DNA.

Twist’s Fast Hybridization and Wash Kit is a revolutionary new system with the flexibility to both save you time and improve the performance of your targeted sequencing efforts. It accommodates your samples, your schedule, and your performance needs: accelerate hybridization to as little as 15 minutes, or adjust the hybridization time to improve coverage for all targeted sequencing applications, including whole exome, custom…

QuikHyb hybridization solution was developed for use in Southern, Northern, slot-blot and plaque-lift formats using randomly labeled radioactive and nonradioactive nucleic acid probes.  Reduces hybridization time from customary 12-24 hours to 1-2 hours  Efficient and sensitive radioactive and nonradioactive detection of nucleic acids  Doubles signal intensity

MVP RNA is application-ready RNA available in small economical pack sizes. Extensive and rigorous quality control including many application specific assays provides assurance that the RNA is intact, full-length and nearly DNA-free.  Extensive quality control ensures high-quality RNA  Eliminates tedious, time consuming RNA isolation procedures  Application ready for real time RT-PCR, miRNA detection and Northern blot anal…

Bio S&T's high-quality RNA can be used directly for NxGen RNA sequencing as well as other downstream applications that require optimal-quality RNA such as quantitative real-time RT-PCR, microRNA cloning and amplification and Northern blotting.

SmartFlare Probes work by recognizing specific native RNA sequences within living cells, therefore there are many possible sequences that you could design to recognize your target of interest. Instead of lysed cells, switch to live cells. And while you’re at it, eliminate sample preparation and transfection steps all together. Live cell RNA detection is now possible, in a single incubation step using inert nanoparticle techno…

Ready-to-transfect CRISPR sgRNAs designed and validated to provide specific and high-efficiency knockout of your target gene

Ideal for identifying potential therapeutic targets involved in the development and progression of disease