The Development of a Sensitive Multi-Residue LC-MS/MS Method for the Quantitative Determination of Mycotoxins in Animal Feedstuffs and Silage Using Xevo TQ-S

In this application note, Waters reports the development of a quantitative method for the determination of 33 relevant mycotoxins in a variety of animal feed and silage extracts. The ACQUITY UPLC I-Class System coupled to a Xevo TQ-S was used for rapid, high quality, and ultra-sensitive analysis of multiple mycotoxins in feed extract. The goal of this application note was to investigate the effect of matrix dilution and enhanced instrument sensitivity to overcome common analytical challenges such as ion suppression and to reduce the effects of matrix variability.