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Prkdc Knockout Rat

SAGE Labs

The Prkdc gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). DNA-PK is required for the non-homologous end joining (NHEJ) pathway of DNA repair, which rejoins double-strand breaks. It is also required for V(D)J recombination, a process that utilizes NHEJ to promote immune system diversity. Mature B and T cells are critical components for an adaptive immune system. DNA-PK kn…

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Pink1 (Park6) Knockout Rat

SAGE Labs

Developed in collaboration with The Michael J. Fox Foundation, this model contains a deletion of the Pink1 (PTEN-induced putative kinase 1) gene, encoding for a serine/threonine protein kinase. Mutations in Pink1 are implicated in early-onset Parkinson’s disease. Pink1 knockout rats show both motor impairments and dopaminergic cell loss, making this a useful model of Parkinson’s disease.Pink1 (Park6) Knockout Rat Characterist…

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Krios G4 Cryo-TEM for Life Sciences

Thermo Fisher Scientific

The Thermo Scientific Krios G4 Cryo-Transmission Electron Microscope (Cryo-TEM) is a compact TEM. The instrument can be installed in labs with a ceiling height below 3.04 m (~10 ft), as the microscope height it below 3 meters. The Krios G4 Cryo-TEM has improved ergonomics for easier sample exchange. Data acquisition set up is easier and faster thanks to enhanced automation, systematic user guidance and advanced performance mo…

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Corning® LSE™ Digital Vortexer, 230V

Corning Life Sciences

The Corning Digital Vortexer is a multipurpose shaker dedicated to a variety of shaking and mixing applications. Three easily removable and interchangeable platforms accommodate many different sample containers such as flasks, bottles, tube racks, plates, boxes, and dishes. The clamp platform has spring loaded retaining bars that adjust to fit vessels of different shapes and sizes. The microplate platform is designed to secure…

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Corning® LSE™ Digital Vortexer, 115V

Corning Life Sciences

The Corning Digital Vortexer is a multipurpose shaker dedicated to a variety of shaking and mixing applications. Three easily removable and interchangeable platforms accommodate many different sample containers such as flasks, bottles, tube racks, plates, boxes, and dishes. The clamp platform has spring loaded retaining bars that adjust to fit vessels of different shapes and sizes. The microplate platform is designed to secure…

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