ChIP DNA Clean & Concentrator™
The ChIP DNA Clean & Concentrator™provides a two minute DNA clean-up from any step in a standard ChIP protocol.
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ChiP-seq
This kit can remove some small primer dimers, faster and easier than AMPxp beads or beads selection. Beads are expensive, if you want to get best results, beads take time.
Review Date: 29 Mar 2022 | Zymo Research
ChIP-qPCR
Really easy to use and more affordable than other brands.
Review Date: 22 Oct 2021 | Zymo Research
ChIPseq samples
Have not seen a better or equivalent product to clean up my reverse cross-linked chromatin immunoprecipitated DNA sample. In spite of the presence of 1% SDS, NaHCO3, DTT & proteinase K in the samples, it effectively cleans up the precious little quantity of my ChIPed DNA without any hassles. There is also flexibility in the volume in which I can elute my samples. I find that the ChIPed DNA sample purified using this kit is highly amenable for ChIPseq library preparation downstream.
Review Date: 7 Jun 2021 | Zymo Research
DNA purification
This kit is very straightforward and easy to use, providing high-quality DNA for downstream applications. I particularly like the versatility in terms of options for different starting material, and the minimal number of spin steps required compared to some similar kits.
Review Date: 25 May 2021 | Zymo Research
Molecular biology/cloning
My lab recently switched to using the Zymo Clean and Concentrator for our cloning projects. This kit is easy to use and actually gives you the appropriate amount of buffer for the number of columns included. Protocol is straightforward and the yield is impressive for the cost.
Review Date: 9 Dec 2020 | Zymo Research
Used for ChIP-seq experiment
Great product! The results are highly reproducible, ease to use. I recommend this for any ChIP seq experiment.
Review Date: 27 Nov 2019 | Zymo Research
Purification of DNA after chromatin cross-linking and pulldown
This DNA Clean and Concentrator kit is easy to use, which makes processing large batches of samples more efficient. The kit is pretty good at ridding contaminants from the samples whilst keeping relatively high yield of DNA.
Review Date: 6 Jun 2019 | Zymo Research
Epigenetics
Using this product to clean DNA after ChIP assay. Protocol is easy to follow, few steps, and DNA is ready for qPCR.
Review Date: 5 Jun 2019 | Zymo Research
PCR product purification
Easy to use and high yield of DNA/RNA. Recommend to purify PCR products.
Review Date: 5 Jun 2019 | Zymo Research
ChIP-Seq and ATAC-Seq cleanup
Zymo kits are very easy to use and it gives high quality and quantity of ChIP or ATAC DNA for downstream sequencing.
Review Date: 5 Jun 2019 | Zymo Research
The Chromatin Immunoprecipitation (ChIP) DNA Clean & Concentrator™ provides a hassle-free method for the rapid purification and concentration of high quality DNA from any step in a standard ChIP protocol.
This includes samples that have undergone reverse cross-linking, Proteinase K or RNase A digestion, mechanical or nuclease-mediated DNA shearing, and samples eluted from chromatin-antibody-bead complexes. The specially formulated ChIP DNA Binding Buffer promotes DNA adsorption to the column in the presence of detergents, antibodies, and proteinases that are often used for ChIP.
This kit may be applied to any routine ChIP procedure to determine DNA concentration of samples that have undergone reverse cross-linking following DNA shearing. It can also be used for the removal of TES, 0.1M NaHCO3 and 1% SDS from DNA eluted from chromatin-antibody-bead complexes and can be used to purify DNA from buffers containing up to 1% SDS or 5% NP-40, Tween-20, Triton X-100 or Sarkosyl.