ViscoStar™
A highly sensitive, on-line differential viscometer for determining the size and conformation of all types of biopolymers and synthetic polymers.
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Easy to use, reliable/reproducible data, and excellent customer service.
Polymer molecular weight and solution properties
I've had my ViscoStar for a little over a year now and I use it along with a miniDAWN Treos II for characterizing polymer molecular weight and solution conformation. The data from both detectors is reproducible and reliable. Even more, both instruments are easy enough for my undergraduate researchers to use and maintain after some initial training. The best part about owning and using instrumentation from Wyatt is their customer service. They are very responsive, knowledgeable and helpful on software issues, and they are well versed in application areas. They have helped my group with all issues that we have come across!
Review Date: 28 May 2020 | Waters | Wyatt Technology
Sensitive, easy to use instrument.
Analyze antibody formulations
Excellent knowledge from the Wyatt Europe team on how the ViscoStar works and the possibilities for use it in new ways.
Review Date: 27 May 2020 | Waters | Wyatt Technology
Great results!
Analysis of fucoidans
We used Viscostar III for the conformational analysis of fucoidans (sulfated polysaccharides). It delivered really exciting results. Easy to use, results very fast!
Review Date: 10 Mar 2020 | Waters | Wyatt Technology
The ViscoStar III is an excellent tool to fully characterize our polymers.
Characterization of polymers
We are very content with the performance of the ViscoStar III and the possibilities it gives us to characterize the architecture and structure of our polymers in both organic and aqueous solvents. In our lab we usually use the ViscoStar III in combination with a DAWN HELEOS II light scattering detector, and still have the possibility to use the ViscoStar III offline for analysis of polymer solutions. The support we get from Wyatt is outstanding, and the quality of the training material that is available online is very good.
Review Date: 24 Aug 2018 | Waters | Wyatt Technology
low usage after purchase, may need some workshop for its applications..
drug delivey
not as high usage compared to Hellos light scattering detectors.
Review Date: 23 Dec 2016 | Waters | Wyatt Technology
Wyatt is a great company and helps to make sure we have access to all the knowledge they possess.
Characterization of Polymers for Paint and Coatings Applications
The Viscostar II has given our lab a powerful tool in characterization of unknown polymers. We have been successfully characterizing raw materials, unknowns, and problem batches for our company for over a year now. We now can also get accurate polymer MW and distribution data where before we could only compare to standards (usually a dissimilar polystyrene). The system does require a relatively skilled person to perform analyses, but Wyatt also paid for training! Every time I have needed any help the highly trained Wyatt staff have answered questions very quickly. The support is wonderful.
Review Date: 24 Jun 2016 | Waters | Wyatt Technology
The ViscoStar™ is an on-line differential viscometer for GPC that measures the intrinsic viscosity (IV) of polymers. It is best used in conjunction with the DAWN™ or miniDAWN™ multi-angle light scattering (MALS) detectors in SEC-MALS-IV analysis to determine absolute molar mass, size, molecular conformation, branching ratio and Mark-Houwink parameters.
The ViscoStar™ may also be used for traditional online IV applications, such as Universal Calibration or Mark-Houwink analyses of molecular weight and size, all supported by Wyatt’s ASTRA® chromatography software.
The ViscoStar™ incorporates several innovations that make it the most advanced differential viscometer available: automated thermal bridge tuning to ensure perfect bridge balance every run, a patented pump pulse suppression system that eliminates pressure fluctuations due to the GPC pump without loss of chromatographic resolution, and dual-Peltier thermal control for optimal isolation of the temperature-sensitive bridge from room temperature variations.
Features:
- Sensitivity: 100 ng of 100 kDa polystyrene in THF at 1 mL/min, with a standard 7.8 x 300 mm GPC column
- Differential pressure noise: < 0.05 Pa
- Differential pressure range: 6.9 kPa
- Dynamic range: 135,000:1 for measuring small and large peaks simultaneously
- Solvent compatibility: compatible with most aqueous and organic solvents
- Capillary bridge autobalance: 10-min thermal, leak-free mechanism
- Delay volumes: 8.1, 5.4 or 2.7 mL standard; 16.2 mL optional
- Temperature control: 4 – 70 °C
- Touch-panel display for immediate access to data, diagnostics and settings
- Software: ASTRA chromatography software provides comprehensive analyses and user-friendly features including HPLC control, “One-click MW” and user-designed reports. Optional 21CFR11 support for GMP.
Applications:
- Polymers: absolute molar mass and size (distributions and moments), conformation and branching, Mark-Houwink parameter determination
- Linear or branched polymers, co-polymers
- Polymers not amenable to SEC-MALS analysis dissolved in semi-opaque or refractive-index-matched solvents, or polymers that fluoresce at the MALS laser wavelength
- Most aqueous and organic solvents
