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The XL1-Blue strains are an all-prupose line of competent cells that are ideal for routine cloning needs. 

When DNA is methylated in a fashion unlike the bacterial host patterns, it is cleaved by the E. coli host restriction systems. 

When DNA is methylated in a fashion unlike the bacterial host patterns, it is cleaved by the E. coli host restriction systems. 

When DNA is methylated in a fashion unlike the bacterial host patterns, it is cleaved by the E. coli host restriction systems.

When DNA is methylated in a fashion unlike the bacterial host patterns, it is cleaved by the E. coli host restriction systems. 

When DNA is methylated in a fashion unlike the bacterial host patterns, it is cleaved by the E. coli host restriction systems. 

The XL1-Blue strains are an all-prupose line of competent cells that are ideal for routine cloning needs. 

The XL1-Blue strains are an all-prupose line of competent cells that are ideal for routine cloning needs.

These competent cells enable a highly efficient, rapid, and reproducible method for introducing random mutations in a cloned gene of interest. This method involves propagating the cloned gene into XL1-Red Competent Cells; an Escherichia coli strain which is deficient in three of the primary DNA repair pathways.

When DNA is methylated in a fashion unlike the bacterial host patterns, it is cleaved by the E. coli host restriction systems. Cleavage of DNA before host replication creates libraries that lack complete representation.