Merck Products & Reviews

Concentrating and purifying samples for MALDI-ToF MS

Recombinant protein A covalently bound to magnetic beads. These beads provide users a rapid, reproducible and efficient reagent for collecting immunocomplexes for chromatin immunoprecipitations (ChIP) assays. Compared with conventional protein A agarose beads, protein A magnetic beads significantly reduce the handling time and mechanical stress on target immunocomplexes.

This kit provides the reagents required for the detection of citrulline-containing proteins by Western blot analysis with the anti-Citrulline antibody. Detection is a two-step process in which citrulline-containing proteins immobilized on nitrocellulose or PVDF are formaldehyde-cross linked to the membrane to improve protein retention, followed by modification of citrulline residues with 2,3-butanedione monoxime and antipyrine…

The ChIPAb+ EZH2, clone AC22 antibody/primer set includes the EZH2, clone AC22 antibody, a negative control antibody (purified mouse IgG), and qPCR primers which amplify a 135 bp region within the promoter of the human MYT-1 gene. The EZH2, clone AC22 antibody and negative control antibodies are supplied in a scalable "per ChIP" reaction size and can be used to functionally validate the precipitation of EZH2-associated chromat…

Protein G covalently coupled by cyanogen bromide to highly cross-linked 4% agarose beads. Stable in all aqueous buffers used in Protein G chromatography.

Beta-Galactosidase Tissue Stain Base Solution. It is one of the components required to visualize the expression of the LacZ reporter gene in fixed tissue.

The UPSTATE colorimetric STAR (Signal Transduction Assay Reaction) ELISA kit is a solid phase sandwich enzyme linked immunosorbent assay that provides a fast, sensitive method to detect specific levels of signaling targets in whole cell extracts. The AKT1 plate is coated with a specific mouse monoclonal anti-AKT1 capture antibody on the microwells of the 96-well clear plate. Many of the reagents are supplied in ready-to use fo…

Five different pore sizes from 0.1 to 5.0 µmPre-sterilized units also availableFast filtration and highly reproducible performanceUse in fixed-angle rotors for 1.5 mL tubes

• High recovery Ultracel regenerated cellulose membrane in a range of molecular weight cut-offs• High retentate recovery of >90%• Vertical membrane reduces concentration polarization for ultra-fast spin times (as fast as 10–15 minutes)• Heat-sealed membrane minimizes downstream extractables• 100% integrity tested for reliable performance• Convenient sample monitoring with translucent housing and volume gradations• Direct pipet…

• High recovery Ultracel regenerated cellulose membrane in a range of molecular weight cut-offs• High retentate recovery of >90%• Vertical membrane reduces concentration polarization for ultra-fast spin times (as fast as 5 minutes)• Heat-sealed membrane minimizes downstream extractables• 100% integrity tested for reliable performance• Convenient sample monitoring with translucent housing and volume gradations• Direct pipette s…

The MILLIPLEX® MAP Rat Thyroid Hormone TSH Panel - Single Plex is used for the simultaneous quantification of the following Rat analytes: TSH

The MILLIPLEX® MAP Rat Stress Hormone Panel is used for the simultaneous quantification of the following Rat analytes: ACTH, Corticosterone, Melatonin

The FlowSight flow cytometer offers high performance in a small package. Its innovative design increases signal and minimizes noise to provide unmatched fluorescence sensitivity. Twelve standard detection channels simultaneously produce brightfield, darkfield and up to ten channels of fluorescence imagery of every cell. With these unique capabilities, the FlowSight enables a broad range of applications. Intuitive: Easy-to-use,…

More than 3000 monoclonal and polyclonal, primary and secondary antibodies.  The Calbiochem® range (incorporating Oncogene Research Products™) now includes the most comprehensive selection of antibodies to MMP’s, G-proteins and Phospho-Proteins on the market today. The extensive range also covers protein kinases, apoptosis, calcium signalling, cancer/cell cycle research, angiogenesis, growth factors and much more. Many product…

Descriptionen_2 Milli-Q Gradient A10 bench-integrated system Depth, cm (in)en_7448 31.5 (12.4) TOC, ppben_1158 1–5 Microorganisms, cfu/mLen_1119 <1 Cartridge Useden_1302 Q-Gard, Quantum, Millipak Brand Nameen_987 Milli-Q Resistivity, compensated to 25 °C (MW·cm)en_1147 18.2 Product Useen_23 Produces 18.2 MW·cm ultrapure water quality with 1–5 ppb TOC levels Height, cm…

96-well filter plate designed and optimized for aqueous solubility assaysDetermining a compound's aqueous solubility has become an essential early measurement to make in the drug discovery process. Poor water solubility can cause problems in many different in vitro testing techniques leading to unreliable results and/or reproducibility problems; insoluble precipitates have been shown to cause false positives in bioassays poten…

Incubate microorganisms, perform albumin tests, paraffin embedding and filter clearing.

Magnetic Bead-Based Isolation of Proteins Millipore’s new PureProteome magnetic beads ensure the rapid and reproducible isolation of proteins. Unlike conventional methods that require centrifugation to pellet the beads then careful aspiration to avoid sample loss, PureProteome magnetic beads are isolated using a magnetic rack. This allows for the total removal of buffers for complete recovery of beads no sample dilution. You…

Detect low-abundant proteins at the femtogram/mL level with the sensitivity and speed of the SMCxPRO™ immunoassay system – a powerful, compact and affordably priced protein quantifier. Discovery depends on detection. When the success of your research requires finding and quantifying low-level proteins, you need equipment you can rely on to detect your target.  This compact, benchtop instrument will fit seamlessly into your…

gradient range 10-15%, pack of 10 gels

12.5% polyacrylamide, pack of 10 gels

Features and Benefits: Purifies total RNA from up to 107 cells or 40 mg of tissue per prep Yields up to 150 μg of pure, concentrated total RNA per prep Recover RNA from as few as 100 cells Simple and efficient–12 to 18 preps in 30 minutes Faster than gravity flow anion exchange methods No cumbersome steps associated with resins and magnetic slurries 40% more purifications per kit than the leading supplier…

Detects apoptotic cells in situ by the indirect TUNEL method, utilizing an anti-digoxigenin antibody that's conjugated to a Fluorescein reporter molecule

Take steps to prevent cell death and avoid poor cell growth by sourcing serum from reputable suppliers who can verify quality and origin - like MilliporeSigma.

 Certified by the Biological Stain Commission