Drug Discovery & Development Products & Reviews

Simplify synthesis and scale-up of potent mRNA with third-generation CleanCap®—proven technology for enhanced in vivo translatability.

Assay (GC): ≥ 99.0%

Biotage® PhyPrep automates the purification of plasmid DNA from cell pellets at the Maxi, Mega and Giga scales. The result is highly pure, endotoxin-free plasmid DNA – the optimal starting point for downstream applications, such as transient transfection. Biotage® PhyPrep comes with everything needed to generate highly pure plasmids, from a simple sample preparation step to a fully automated purification procedure, freeing up…

The Biotage ® Initiator Peptide Workstation

wavePREP is an efficient, rapid, and safe tool for the post-processing step in the oligos production. Its process combines cleavage and deprotection into a single step, ensuring both a superior workflow and product yields by removing the evaporation phase.

The Milestone synthWAVE is designed for safe, reliable and reproducible scale-up of microwave enhanced chemical reactions. The synthWAVE is capable of higher temperature and pressure than any other microwave reactors. Milestone synthWAVE features the unmatched Single Reaction Chamber (SRC) patented technology that ensures scale, reaction screening, highest temperature and pressure. It is able to handle single or multiple react…

The new Milestone flexiWAVE overcomes the limitation of conventional microwave synthesis reactors, as it consists of a single microwave platform that, in combination with specific accessories, allows the chemists to perform classic glassware and high pressure synthesis, as well as solid-phase reactions.

Twist Multiplexed Gene Fragments are double stranded gene fragment sequences of up to 500 base pairs in length that are delivered as a pool instead of one fragment per well matrix.

The AptaFluor® SAH Methyltransferase Assay Kit enables ultra-sensitive, direct detection of SAH—the universal product of methyltransferase reactions—using a riboswitch-based TR-FRET format. With no coupling enzymes required, it delivers high signal-to-background, Z’ ≥ 0.7, and is fully HTS-compatible for drug discovery and inhibitor screening.

BellBrook Labs’ Lead Discovery Services deliver expert support for hit-to-lead efforts. From inhibitor screening and potency profiling to residence-time, mechanism-of-action, and selectivity studies, their team tailors efficient enzymatic assays to your program—accelerating lead advancement with precision and flexibility.

The Transcreener® cGAMP cGAS Assay Kit offers mix-and-read fluorescent detection of cGAMP—the product of cGAS activity—with no coupling enzymes required. Available in FP or TR‑FRET readouts (far-red tracers minimize interference), it’s HTS-ready (Z’ ≥ 0.7), automation-compatible, and validated on 96‑, 384‑, and 1536‑well formats for enzyme kinetics, SAR, and inhibitor screening.

The CD73 activity assay for HTS and hit-to-lead. Measure specific activity of CD73 in a simple mix-and-read format. The kit is designed for compound library screening and follow-up inhibitor discovery.

The Transcreener dAMP Exonuclease Assay directly measures dAMP produced by exonuclease enzymes as they cleave polynucleotides. 

The Transcreener® GDP GTPase Assay Kit directly measures GDP produced during GTP hydrolysis in a homogeneous mix‑and‑read format—no coupling enzymes needed. Compatible with GTPases, GAPs, and GEFs, it supports FP, FI, and TR‑FRET readouts using far‑red tracers to reduce interference. HTS‑ready with excellent sensitivity (Z′ ≥ 0.7), it streamlines screening and profiling workflows.

Express proteins—even large and challenging constructs—and conduct screening studies directly in HEK293 cells using efficient, reliable TARGATT™ large knock-in technology. With the ability to efficiently and site-specifically insert 20+ kb of DNA (more with nested reactions) into the reliable H11 safe harbor site, TARGATT™ HEK293 kits move you to the next inflection point faster.

Express proteins—even large and challenging constructs—and conduct screening studies directly in CHO K1 cells using efficient, reliable TARGATT™ large knock-in technology. With the ability to efficiently and site-specifically insert 20+ kb of DNA (more with nested reactions) into the reliable H11 safe harbor site, TARGATT™ CHO K1 kits move you to the next inflection point faster.

Build tomorrow’s cell therapies and cell-based disease models using TARGATT™ Human Induced Pluripotent Stem Cell (hiPSC) Kits. With the ability to efficiently and site-specifically insert 20+ kb of DNA (more with nested reactions), TARGATT™ hiPSC technology enables expression of large proteins and multi-protein complexes in hiPSC-derived human cell lines.

Simplify your workflow and save valuable laboratory time with the fully automated MACS® Sampler, a perfect extension for the MACS® Matchmaker instrument, allowing you to fully integrate automatization solution for your interaction studies.

With the MACS® Matchmaker you can experience a robust platform that delivers quantitative data on binder affinity, kinetics, and specificity in complex samples. Unlock new possibilities in your research today – because every target deserves its perfect match!

At Elephas, we developed a transformative platform that evaluates the likelihood of response to immuno-oncology therapy. For five years, our experts have focused on solving the scientific challenges that stood in the way of leveraging live tumor tissue to test response. Today, our platform enables real-time characterization of immune response by preserving the tumor microenvironment from a live core needle biopsy and mitigatin…

Comprehensive Quantitation & Confident Structural ID

Ultra-Precise Quantitation and Chiral Analysis, Streamlined