Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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LigaFast™ Rapid DNA Ligation System

Promega Corp.

The LigaFast™ Rapid DNA Ligation System is designed for the efficient ligation of sticky-ended DNA inserts into plasmid vectors in just 5 minutes (blunt-ended inserts in as little as 15 minutes).   Rapid ligation is based on the combination of T4 DNA Ligase with a unique 2X Rapid Ligation Buffer to speed up and streamline your cloning experiments. The LigaFast™ System is designed to eliminate any further purification pri…

4.7/5.0
|2 Reviews

Thermo Scientific™ EZ-Link™ Sulfo-NHS-LC-Biotin and Labeling Kits

Thermo Fisher Scientific

The most popular amine-reactive biotinylation reagent for antibody labeling Thermo Scientific™ EZ-Link™ Sulfo-NHS-LC-Biotin and Labeling Kits Features: Water-soluble analog of NHS-LC-Biotin Reacts with primary amines at pH 7-9 in non-amine-containing buffers such as borate, carbonate or phosphate buffers Negative charge of -SO3 group keeps biotinylation localized at the cell surface Creates an amide bond Applicatio…

4.7/5.0
|2 Reviews

PCT™ Pre-Crystallization Test

Hampton Research

The PCT Pre-Crystallization Test is used to determine the appropriate protein concentration for crystallization screening. Sample concentration is a significant crystallization variable. Samples too concentrated can result in amorphous precipitate, while samples too dilute can result in clear drops. Precipitate and clear drops are typical crystallization screen results for reagent conditions which do not promote crystallizati…

4.7/5.0
|1 Review

ViaFect™ Transfection Reagent

Promega Corp.

ViaFect™ Transfection Reagent allows high-efficiency transfection of a wide range of cell types, including iPS Cells, without compromising cell viability.   ViaFect™ Transfection Reagent enables the design of biologically relevant assays in workhorse adherent cell models, suspension cells important for studying cell signaling, and even differentiated cell lines derived from stem cells. ViaFect™ Transfection Reagent offer…

4.9/5.0
|4 Reviews

GloMax® Discover Microplate Reader

Promega Corp.

This ready-to-use multimode detection system includes: high-performance luminescence, fluorescence, UV-Visible absorbance, BRET and FRET, two-color filtered luminescence and kinetic measurement capabilities.   The GloMax® Discover System is a high-performance multimode detection instrument developed with Promega reagent chemistries to provide a simple means of detecting advanced chemistries. This instrument provides…

4.8/5.0
|8 Reviews

ADP-Glo™ Kinase Assay

Promega Corp.

ADP-Glo™ Kinase Assay is a luminescent kinase assay that measures ADP formed from a kinase reaction; ADP is converted into ATP, which is converted into light by Ultra-Glo™ Luciferase.   The luminescent signal positively correlates with kinase activity. The assay is well suited for measuring the effects chemical compounds have on the activity of a broad range of purified kinases, making it ideal for both primary scre…

5.0/5.0
|2 Reviews

Ovation® RNA-Seq System V2

NuGEN

Our latest generation Ovation RNA-Seq System V2 provides a fast and simple method for preparing amplified cDNA from total RNA for RNA-Seq applications, now with enhanced transcript coverage and uniform distribution of sequencing reads. Amplification is initiated at the 3' end as well as randomly throughout the whole transcriptome in the sample. This feature makes the Ovation RNA-Seq System V2 ideal for amplification prior to…

4.9/5.0
|2 Reviews

Mosaic Sample Management Software

Titian Software Limited

Titian Software's Mosaic is a leading sample management software solution for life science laboratories, which tracks and manages every step of the sample lifecycle for any type of sample. Mosaic suits any scale of company as its library of ready-to-go modules are configured to meet your specific needs for sample management.

4.7/5.0
|2 Reviews

Hei-VAP Precision

Heidolph Instruments GmbH

Most demanding applications and finest integrated vacuum control capabilities. Includes leading safety standards and features for superior ease of use and reduced cost of ownership. Reduce your process times significantly by using three programs for automated distillation.Hei-VAP Precision Features: Available in hand lift or motor lift configurations Experience the advantages of our large 4.3 '' color graphic display wh…

5.0/5.0
|2 Reviews

Thermo Scientific™ Pierce™ M-PER™ Mammalian Protein Extraction Reagent

Thermo Fisher Scientific

For highly efficient total protein extraction from cultured mammalian cells. The complete cell lysis reagent is a nondenaturing detergent formulation that dissolves cell membranes and extracts total soluble cellular protein in only 5 minutes. M-PER Reagent requires little or no mechanical disruption and yields more protein than freeze/thaw cycles and sonication.This mammalian cell lysis reagent is so efficient that adherent c…

4.7/5.0
|1 Review

PTR-QMS 500

Ionicon Analytik

The High-Sensitivity PTR-QMS 500 is an ultra-sensitive real-time monitor for volatile organic compounds (VOCs) and has a detection limit of < 1 pptv. The High-Sensitivity PTR-QMS 500 is the most sensitive commercial PTR-MS instrument available in the market and represents the 4th and most advanced generation of IONICON PTR-MS systems. It is the successor of the world's bestselling PTR-MS system: the IONICON High-Sensitivity P…

4.7/5.0
|2 Reviews

Polydimethylsiloxane/Divinylbenzene (PDMS/DVB) SPME Fibers

Sigma-Aldrich Supelco

Polydimethylsiloxane/Divinylbenzene (PDMS/DVB) SPME Fibers.Solid Phase Microextraction (SPME) is an innovative, solvent-free sample prep technology that is fast, economical, and versatile. SPME uses a fiber coated with a liquid (polymer), a solid (sorbent), or a combination of both. The fiber coating removes the compounds from your sample by absorption in the case of liquid coatings or adsorbtion in the case of solid coatings.…

4.5/5.0
|2 Reviews

Polydimethylsiloxane (PDMS)- non-polar SPME Fibers

Sigma-Aldrich Supelco

Polydimethylsiloxane (PDMS)- non-polar SPME Fibers.Solid Phase Microextraction (SPME) is an innovative, solvent-free sample prep technology that is fast, economical, and versatile. SPME uses a fiber coated with a liquid (polymer), a solid (sorbent), or a combination of both. The fiber coating removes the compounds from your sample by absorption in the case of liquid coatings or adsorbtion in the case of solid coatings. The S…

4.9/5.0
|2 Reviews

PEAKS Studio

Bioinformatics Solutions Inc.

A fully functional desktop-based proteomics workbench, PEAKS Studio offers a complete proteomics software. Users are able to perform de novo sequencing, protein identification (PEAKS DB), multi-engine protein identification (PEAKS inChorus), PEAKS PTM, Sequence Homology Searching (SPIDER) and Quantification (as an optional node).Tools: Load and Process (RAW) Instrument Data De Novo Sequencing Protein Database Search E…

5.0/5.0
|1 Review


Cell Culture Flasks

VWR International Ltd

Crystal clear virgin PS, sterile and certified non pyrogenic. VWR Collection flasks are vacuum gas plasma treated for consistent cell attachment and growth. Vented caps incorporate a 0,22 µm hydrophobic filter to allow gas exchange and minimise risk of contamination. Plug seal caps can be used in closed systems (providing a liquid and gas-tight seal) or used in an open system (simply unscrew the cap one quarter of a turn).Fea…

4.8/5.0
|3 Reviews

PCR Plates - Semi-Skirted

SSI - Scientific Specialties, Inc

• Comprehensive thermal cycler compatibility.• Ultra-thin walls produce efficient thermal transfersduring amplifications.• High contrast printed letters and numerals for rapid sample identification.• Bar-coded semi-skirted and full-skirted plates enable convenient sample identification and trackingthroughout analysis.Part Numbers:3420-00: standard3421-00: low profile3425-00: raised rim, standard well, ABI® type3426-00: low pro…

5.0/5.0
|1 Review


Preddator Bulk Reagent Dispenser

Redd&Whyte

The world’s most flexible, non-contact bulk reagent dispenser. The Preddator is a low-volume, non-contact, bulk reagent dispenser that was designed and developed in close collaboration with research scientists from two major pharmaceutical companies. The Preddator now offers an unparalleled set of features and benefits to users of bulk reagent dispensers. Features & Benefits: Simple fluid pathway - Reduces dead volume…

4.7/5.0
|2 Reviews


Quik Screen

Hampton Research

Grid Screen Salt HT combines Grid Screen Ammonium Sulfate, Grid Screen Sodium Malonate, Quik Screen and Grid Screen Sodium Chloride into a single 96 Deep Well block format. The block contains 1 ml of each reagent. Features: A systematic grid screen varying salt or polymer or organic versus pH Samples pH 4 to 9 Combine reagents within or between screens to customize your screen Combine reagents between rows or colum…

4.7/5.0
|1 Review

Savant™ Refrigerated Vapor Traps

Thermo Fisher Scientific

Condense and trap a wide variety of solvent vapors that can contaminate and degrade vacuum pump oil with Thermo Scientific™ Savant™ Refrigerated Vapor Traps. Features: Rapid cooling time minimizes waiting period Easy to remove glass flask for quick solvent changes Rapidly cools to operating temperature Easy to use glass condensation flask allows for the collection of liquid into a self contained jar for easy draining…

4.6/5.0
|3 Reviews

DURAN® HPLC Bottle System

SCHOTT North America, Inc.

DURAN® HPLC Bottle with 4 port GL45 Cap.Safe transfer of HPLC liquids and also used for sterile transfer of liquid media. Complete system including DURAN® Pressure Plus Bottle plus 4 port GL45 PP screw cap. DURAN Pressure Plus bottles are designed and manufactured with a modified geometry for pressure/vacuum resistance from -1 to +1.5 bar in accordance with ISO 4796-1. With pressure load the following apply; thermal shock res…

4.7/5.0
|1 Review

EnSight™ Multimode Plate Reader

Revvity

The EnSight ® multimode plate reader offers HTS Alpha and Ultra-sensitive Luminescence technologies alongside conventional multimode detection technologies. When equipped with a quad monochromator, the EnSight plate reader can improve performance for absorbance and fluorescence detection. In addition, stacker and robotic interface options are available, ideal for automation. The system’s modular design, combined with workflo…

5.0/5.0
|1 Review

Mass Spec-Compatible Yeast and Human Protein Extracts

Promega Corp.

The mass spectrometry-compatible yeast and human protein extracts are designed specifically for mass spectrometry applications.   The extracts are predigested and cleaned up by solid-phase extraction for immediate use in liquid chromatography/mass spectrometry (LC/MS) analysis. Both the yeast and human extracts also are available in an intact undigested form to provide a test material for optimizing mass spec protei…

5.0/5.0
|1 Review