Drug discovery > Target Discovery Products & Reviews

FuGENE® HD Transfection Reagent is a novel, nonliposomal formulation designed to transfect DNA into a wide variety of cell lines with high efficiency and low toxicity. The protocol does not require removal of serum or culture medium and does not require washing or changing of medium after introducing the reagent/DNA complex. Additionally, the FuGENE® HD Transfection Reagent has been shown to support transfection in che…

The NanoBRET™ Target Engagement (TE) Intracellular BET BRD Assay measures compound binding at select BET bromodomain target proteins within intact cells. This target engagement assay is based on the NanoBRET™ System, an energy transfer technique designed to measure molecular proximity in living cells

Single-Use Ligands for High-Resolution lmaging in Live Cells

The RealTime-Glo™ MT Cell Viabiilty Assay measures viability of cells in a non-lytic, real-time live-cell format, saving time, cells and reagent costs.

The Dual-Luciferase® Reporter (DLR™) Assay System(a–f) provides an efficient means of performing two reporter assays. In the DLR™ Assay, the activities of firefly (Photinus pyralis) and Renilla (Renilla reniformis or sea pansy) luciferases are measured sequentially from a single sample. The firefly luciferase reporter is measured first by adding Luciferase Assay Reagent II (LAR II) to generate a luminescent signal lasting at l…

High-throughput quantitation of firefly (Photinus pyralis) luciferase expression in mammalian cells is commonly performed by batch processing of 96- and 384-well plates. Steady-Glo® Luciferase Assay System(a,b,c) is designed for this purpose by providing long-lived luminescence when added to cultured cells. The homogeneous assay provides signal half-lives of over 5 hours in commonly used cell culture media without prior sample…

The CellTiter-Blue® Cell Viability Assay provides a homogeneous, fluorescent method for monitoring cell viability. The assay is based on the ability of living cells to convert a redox dye (resazurin) into a fluorescent end product (resorufin). Nonviable cells rapidly lose metabolic capacity and thus do not generate a fluorescent signal. The homogeneous assay procedure involves adding the single reagent directly to cells cultur…

The Dual-Glo® Luciferase Assay System is a homogeneous reagent system that enables fast and simple quantitation of a stable luminescent signal from two reporter genes in a single sample. This convenient "add-and-read" system generates both firefly and Renilla luciferase luminescence signals from cells that have not been preconditioned or prelysed. With the Dual-Glo® System, internal controls can be established to minimize s…

Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity

The Promega CytoTox 96® Non-Radioactive Cytotoxicity Assay is a colorimetric alternative to radioactive cytotoxicity assays. The CytoTox 96® Assay quantitatively measures lactate dehydrogenase (LDH), a stable cytosolic enzyme that is released upon cell lysis, in much the same way as [51Cr] is released in radioactive assays. Released LDH in culture supernatants is measured with a 30-minute coupled enzymatic assay that result…

The Waters SYNAPT G2-Si High Definition Mass Spectrometry provides complete characterization of complex mixtures and molecules with unique levels of MS performance, industry leading informatics and unparalleled platform versatility.Through high-efficiency T-Wave™ ion mobility you can get superior separation, enhance the peak capacity, specificity and sensitivity of your analysis and transform your targeted and untargeted workf…

Information-rich, robust quantitative data, accessible to everyone.

The GlycoWorks Product Line was developed and designed to compliment the existing Waters Glycan Application Solution. Concentrating on 2-AB labeled N-Glycan, this sample preparation offering and complimentary standards provides a unique, comprehensive yet versatile solution. The GlycoWorks HILIC uElution Plate is ideal for removing contaminants like salts and detergents from hydrophilic analytes, such as carbohydrates, prior…

The SQ Detector 2 is compatible with the broadest range of chromatography platforms and ionization sources, the SQ Detector 2 is the ultimate single quadrupole mass detector for chromatography.IntelliStart™ guarantees maximum system performance and usability for reproducible results. A wide mass range enables uncompromised analysis of both low and high molecular weight species while versatile chromatographic options ensure com…

GC capabilities for today's advanced MS technologies

Xevo G2-XS QTof - eXtreme Sensitivity, eXtraordinary Selectivity, eXceptional Solutions. For the scientist who needs to identify, quantify and confirm the broadest range of compounds in the most complex and challenging samples the Xevo G2-XS QTof provides maximum robustness with no compromise in performance, class-leading real-world quantitative sensitivity, the highest quality, most comprehensive qualitative information, fle…

Xevo G2-XS Tof - Performance, robustness, and flexibility made accessible to everyone. For the scientist who needs to identify, quantify and confirm the broadest range of compounds in the most complex and challenging samples the Xevo G2-XS Tof provides maximum robustness with no compromise in performance, the highest quality, most comprehensive qualitative and quantitative information, flexibility to adapt to changing needs,…

The next-gen protein and nucleic acid quantification system

Media, Process Resins; For Hydrophobic Interaction Chromatography; Tosoh Toyopearl Ether-650M, 65 micrometer; Matrix: Polymer; Container Size: 100mL

The Specac flagship Autotouch Press is designed for high volume laboratory sample preparation for XRF and other elemental analysis techniques, capable of pressing a single sample in under two minutes when augmented with the Apex automated die system.

mRNA sequencing (mRNA-seq) is a potent method for gene expression exploration, it unveils mRNA dynamics, different gene expression and regulatory mechanisms with precision.

The CyFlow® Counter is a fully equipped portable and ultra-compact desktop flow cytometer.

Family of ultra-compact, high-end, multi-laser, benchtop flow cytometry systems.

The Sci-Print MP2+ is compatible with a variety of microplates and deep well blocks. The system includes two vertical stackers for loading and unloading of microplates. Plates are loaded into an input stacker, processed at the printing platform, and moved to the output stacker.

The Sci-Print VX2 is a fully automated tube labeling system, capable of printing and applying labels to tubes ranging from 0.5 mL to 50 mL in size. The system can be used stand-alone or configured to sort racked tubes, receive bulk tubes, uncap/recap, fill and/or scan barcodes.