Drug discovery > Target Discovery Products & Reviews

The NanoBRET™ Target Engagement (TE) Intracellular BET BRD Assay measures compound binding at select BET bromodomain target proteins within intact cells. This target engagement assay is based on the NanoBRET™ System, an energy transfer technique designed to measure molecular proximity in living cells

Single-Use Ligands for High-Resolution lmaging in Live Cells

The RealTime-Glo™ MT Cell Viabiilty Assay measures viability of cells in a non-lytic, real-time live-cell format, saving time, cells and reagent costs.

The Dual-Luciferase® Reporter (DLR™) Assay System(a–f) provides an efficient means of performing two reporter assays. In the DLR™ Assay, the activities of firefly (Photinus pyralis) and Renilla (Renilla reniformis or sea pansy) luciferases are measured sequentially from a single sample. The firefly luciferase reporter is measured first by adding Luciferase Assay Reagent II (LAR II) to generate a luminescent signal lasting at l…

High-throughput quantitation of firefly (Photinus pyralis) luciferase expression in mammalian cells is commonly performed by batch processing of 96- and 384-well plates. Steady-Glo® Luciferase Assay System(a,b,c) is designed for this purpose by providing long-lived luminescence when added to cultured cells. The homogeneous assay provides signal half-lives of over 5 hours in commonly used cell culture media without prior sample…

The CellTiter-Blue® Cell Viability Assay provides a homogeneous, fluorescent method for monitoring cell viability. The assay is based on the ability of living cells to convert a redox dye (resazurin) into a fluorescent end product (resorufin). Nonviable cells rapidly lose metabolic capacity and thus do not generate a fluorescent signal. The homogeneous assay procedure involves adding the single reagent directly to cells cultur…

The Dual-Glo® Luciferase Assay System is a homogeneous reagent system that enables fast and simple quantitation of a stable luminescent signal from two reporter genes in a single sample. This convenient "add-and-read" system generates both firefly and Renilla luciferase luminescence signals from cells that have not been preconditioned or prelysed. With the Dual-Glo® System, internal controls can be established to minimize s…

Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity

The Promega CytoTox 96® Non-Radioactive Cytotoxicity Assay is a colorimetric alternative to radioactive cytotoxicity assays. The CytoTox 96® Assay quantitatively measures lactate dehydrogenase (LDH), a stable cytosolic enzyme that is released upon cell lysis, in much the same way as [51Cr] is released in radioactive assays. Released LDH in culture supernatants is measured with a 30-minute coupled enzymatic assay that result…

The Genizer HandExtruder is a cost-effective tool for micro liposome extrusion. Users manually push the syringe plunger to force the sample through a filter membrane, repeating the process 5 to 10 times for consistent liposome sizes.

Power and efficiency for large-scale genomics. The HiSeq 2500 System features two run modes, rapid run and high output run mode, and the ability to process one or two flow cells simultaneously. This provides a flexible and scalable platform that supports the broadest range of applications and study sizes. No other system lets you perform so many applications so quickly and easily. Choose between rapid run and high output mode…

Disruptive Technology for mAb Screening and Characterization.

Through its exceptional image quality and the widest size range available, FlowCam® 8000 represents state-of-the-art particle imaging technology. Analyze thousands of particles in less than a minute and comprehensively characterize the size, count, morphology, and identity of subvisible and visible particulates in their native solvent.

Media, Process Resins; For Hydrophobic Interaction Chromatography; Tosoh Toyopearl Ether-650M, 65 micrometer; Matrix: Polymer; Container Size: 100mL

mRNA sequencing (mRNA-seq) is a potent method for gene expression exploration, it unveils mRNA dynamics, different gene expression and regulatory mechanisms with precision.

The CyFlow® Counter is a fully equipped portable and ultra-compact desktop flow cytometer.

Family of ultra-compact, high-end, multi-laser, benchtop flow cytometry systems.

The Sci-Print MP2+ is compatible with a variety of microplates and deep well blocks. The system includes two vertical stackers for loading and unloading of microplates. Plates are loaded into an input stacker, processed at the printing platform, and moved to the output stacker.

The Sci-Print VX2 is a fully automated tube labeling system, capable of printing and applying labels to tubes ranging from 0.5 mL to 50 mL in size. The system can be used stand-alone or configured to sort racked tubes, receive bulk tubes, uncap/recap, fill and/or scan barcodes.

The next generation STELLARIS confocal platform is your fast track to rewarding research. Power. Potential. Productivity.

High-pressure freezing with the possibility of light and electrical stimulation

ULTRASENSITIVE. RELIABLE. COMFORTABLE.

HIGH-THROUGHPUT MICROPLATE WASHING & DISPENSING

ULTRASENSITIVE, RELIABLE AND ACCURATE LUMINESCENCE MEASUREMENT  

High-quality microplates for your applications