Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Gallios™ Flow Cytometer

Beckman Coulter Diagnostics

The Gallios Flow Cytometer is a research system that delivers analytical excellence by coupling extraordinary sensitivity, resolution and dynamic range with high-speed data collection. Designed to fit your needs, today and tomorrow, the Gallios flow cytometer provides efficient acquisition of excellent quality data from up to 10 colors with advanced optical design for enhanced sensitivity for multicolor assays. With customize…

4.1/5.0
|4 Reviews
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FastPrep-24™ 5G

MP Biomedicals

The FastPrep-24™ 5G Instrument is quite simply the most advanced sample preparation system ever!   The only high-speed benchtop homogenizer featuring microprocessor-controlled, Hi-Def Touch Screen Programming makes the 5G the ultimate in ease, speed and performance for sample preparation applications where it is necessary to grind, lyse, or homogenize difficult and routine samples, allowing easy and reproducible isolatio…

4.3/5.0
|22 Reviews
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ISOLUTE® SLE +

Biotage

ISOLUTE SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, extracting up to 400 µL aqueous sample.

4.2/5.0
|3 Reviews
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Isolera

Biotage

Isolera, a compact flash purification system with intelligent features, enables chemists to easily achieve better separations. The patented TLC-to-gradient feature automatically creates elution gradients and suggests cartridge and sample size. Collect fractions using two wavelengths, adjust the flow rate from 1 to 200 mL/min as needed and use up to four solvents in a single gradient, for maximum purity and yield.

4.0/5.0
|2 Reviews
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PhyTip® Chromatography Columns for HTP Protein Purification

Biotage

PhyTip® Columns offer automated, flexible and scalable solution for biomolecule separation. The PhyTip® technology platform enables chromatography using automated bench top platforms (for up to 12 samples in parallel) and robotic liquid handling systems (for up to 96 samples in parallel). The unique design of the PhyTip® affinity columns allows bidirectional flow of the sample through the column to maximize the use of the resi…

4.2/5.0
|2 Reviews
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twin.tec PCR Plate 96 and 384

Eppendorf

Eppendorf® twin.tec PCR plates give you the advantages that come from combining two materials: the wells are manufactured from virgin polypropylene, the most successful material used for PCR tubes; polycarbonate, an especially rigid material, forms the plate deck and the skirt. This one-piece design is achieved by an innovative injection moulding process, twin-shot technology. Polycarbonate enhances the mechanical stability an…

4.4/5.0
|2 Reviews
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Exchangeable thermoblock for 4 slides

Eppendorf

Product features Exchangeable thermoblock for 1-4 slides Basic device: Thermomixer comfort, ThermoStat plus Increased signal intensity, improved signal to background ratio, very good reproducibility High level of spatial and temporal temperature stability during hybridization System guarantees the highest level of homogeneity of the hybridization parameters Water in the reservoir pads guarantees high air humidity…

4.3/5.0
|1 Review
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epMotion® 5075

Eppendorf

 The epMotion 5075 is the ideal solution for diverse liquid handling demands. It offers the same outstanding accuracy and precision as epMotion 5070 and 5073. The available options make the 5075 an excellent and flexible device for applications such as NGS library preparation, real-time PCR set-up, magnetic bead-based and filter-based purification, cell-based assays or any routine pipetting tasks.

4.4/5.0
|9 Reviews
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epMotion® 5070

Eppendorf

  Our smallest member of the epMotion family is the most compact solution for accurate and reproducible automated pipetting. This makes the epMotion 5070 a perfect match for any routine application such as PCR and qPCR set up, serial dilutions, reagent distribution, sample transfer from tubes to plates, and sample normalization.

4.0/5.0
|1 Review
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Eppendorf DASGIP® Parallel Bioreactor System

Eppendorf

DASGIP Parallel Bioreactor Systems for R&D and process development in both cell culture and microbiology allow for advanced bioprocess control and automation. Parallel processing, precise control of all relevant parameters, user-defined profiles and innumerable automation features result in accelerated and highly efficient process development. Our DASware software solutions support DoE, process historians and comprehensive…

3.7/5.0
|2 Reviews

Eppendorf New Brunswick™ BioFlo®/CelliGen® 510

Eppendorf

BioFlo 510 Fermentors and CelliGen 510 Bioreactors are intermediate systems ideal for pilot to small scale production processes. The modular design features a wide variety of standard options allowing this system to be flexible enough to meet most process requirements.   Eppendorf New Brunswick™ BioFlo®/CelliGen® 510 Working volumes: 10.75 L to 32.0 L Applications: Laboratory and pilot scale fermentat…

4.3/5.0
|1 Review

Clean Screen® FASt Well Plate

UCT, Inc.

The FASt Well Plate is a novel approach to improved sample preparation for LC/MS analysis. The well plate employs a one step process to prepare urine samples for analysis of multiple drugs and metabolites. By quickly and efficiently reducing the amount of unwanted matrix and particulates in the final sample, the analysis can proceed with less chance of matrix suppression and LC column clogging.

4.3/5.0
|1 Review
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CellTox™ Green Cytotoxicity Assay

Promega Corp.

The CellTox™ Green Cytotoxicity Assay measures changes in membrane integrity that occur as a result of cell death. The assay is intended to assess cytotoxicity in cell culture after experimental manipulation. The assay system uses a proprietry asymmetric cyanine dye that is excluded from viable cells but preferentially stains the DNA from dead cells. When the dye binds DNA released from cells, its fluorescence properties are s…

4.3/5.0
|1 Review
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QuantiFluor® dsDNA System

Promega Corp.

The QuantiFluor® dsDNA System contains a fluorescent DNA-binding dye that enables sensitive quantitation of small amounts of double-stranded DNA (dsDNA) in solution.   The quantitation of dsDNA is a very important step in many biological applications, particularly in standard molecular biology techniques. The dye shows minimal binding to single stranded DNA (ssDNA) and RNA, allowing specific quantitation of dsDNA. The…

4.3/5.0
|2 Reviews
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Recombinant RNasin® Ribonuclease Inhibitor

Promega Corp.

Recombinant RNasin® Ribonuclease Inhibitor reliably protects your RNA samples from RNase degradation.   RNases are ubiquitous and degradation can cause significant damage to RNA, hindering downstream reactions. Protect your sample with the most robust inhibitor available-- Recombinant RNasin® Ribonuclease Inhibitor. Recombinant RNasin Ribonuclease Inhibitor Features & Benefits:   Inhibits a broad spectrum o…

4.2/5.0
|3 Reviews
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CellTiter-Glo® 3D Cell Viability Assay

Promega Corp.

The CellTiter-Glo® 3D Cell Viability Assay is a homogeneous method to determine the number of viable cells in 3D cell culture based on quantitation of the ATP present, which is a marker for the presence of metabolically active cells.   This ready-to-use reagent is based on the original CellTiter-Glo® Luminescent Cell Viability Assay chemistry and eliminates the need to combine buffer with lyophilized substrate when prepa…

4.3/5.0
|5 Reviews
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FuGENE ® HD Transfection Reagent

Promega Corp.

FuGENE® HD Transfection Reagent is a novel, nonliposomal formulation designed to transfect DNA into a wide variety of cell lines with high efficiency and low toxicity. The protocol does not require removal of serum or culture medium and does not require washing or changing of medium after introducing the reagent/DNA complex. Additionally, the FuGENE® HD Transfection Reagent has been shown to support transfection in che…

4.3/5.0
|6 Reviews
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NanoBRET™ Target Engagement BET BRD Assays

Promega Corp.

The NanoBRET™ Target Engagement (TE) Intracellular BET BRD Assay measures compound binding at select BET bromodomain target proteins within intact cells. This target engagement assay is based on the NanoBRET™ System, an energy transfer technique designed to measure molecular proximity in living cells

4.3/5.0
|1 Review
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Dual-Luciferase ® Reporter Assay System

Promega Corp.

The Dual-Luciferase® Reporter (DLR™) Assay System(a–f) provides an efficient means of performing two reporter assays. In the DLR™ Assay, the activities of firefly (Photinus pyralis) and Renilla (Renilla reniformis or sea pansy) luciferases are measured sequentially from a single sample. The firefly luciferase reporter is measured first by adding Luciferase Assay Reagent II (LAR II) to generate a luminescent signal lasting at l…

4.4/5.0
|9 Reviews
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