ADME-Toxicology Products & Reviews

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ADME-toxicology (ADME-Tox) studies are used in pharmacology and pharmacokinetics to assess the activity/toxicity of drugs <i>in vivo</i> or <i>in vitro</i>. Find bioassays for absorption, distribution, metabolism, and excretion of drug molecules including cytotoxicity, transporter/permeability, metabolism and activity assays as well as hepatocytes and cell lines for ADME. Find the best ADME-toxicology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Invitrogen™ Annexin V Pacific Blue™ Ready Flow Conjugate

Thermo Fisher Scientific

Annexin V Pacific Blue Ready Flow Conjugate is a bright, easy-to-use stain for apoptosis with high affinity for phosphatidylserine (PS), which becomes exposed on the outer leaflet of cells undergoing apoptosis. The Annexin V Pacific Blue conjugate is excitable at 410 nm with an emission peak at 455 nm.FeaturesStable at room temperatureConvenient, ready-to-use format—no need to dilute, weigh, or pipetteCan be added directly to…

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PE/Cy7 Annexin V

BioLegend

Available in 25, 100 or 300 test packs. Annexin V (or Annexin A5) is a member of the annexin family of intracellular proteins that binds to phosphatidylserine (PS) in a calcium-dependent manner. PS is normally only found on the intracellular leaflet of the plasma membrane in healthy cells, but during early apoptosis, membrane asymmetry is lost and PS translocates to the external leaflet. Fluorochrome-labeled Annexin V can t…

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CL100-ProliFiler

ProQinase GmbH

ProQinase's CL100-ProliFiler is a standard service package comprising IC50 determination of your test compounds on the proliferation response of a defined panel of 100 tumor cell lines.

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Trypan Blue

Bio-Rad

10 x 1.5 ml, sufficient for 1,500 counts (10 µl/count), 0.4% in 0.81% sodium chloride and 0.06% potassium phosphate dibasic solution, sterile filtered, for use with TC10™ or TC20™ automated cell counter.

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CFDA-SE

Bio-Rad

Use the CFDA-SE (5[6]Carboxyfluorescein diacetate, succinimidyl ester) cell-permeable dye to monitor cell population health.

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ReadiDrop™ Propidium Iodide

Bio-Rad

Commonly used in flow cytometry experiments for excluding dead cells, the propidium iodide solution enters a compromised cell and binds to double-stranded DNA/RNA by intercalating between base pairs.

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ReadiDrop™ 7-AAD

Bio-Rad

The ReadiDrop™ 7-aminoactinomycin D (7-AAD) cell viability assay is designed as a ready-to-use 7-AAD solution, which binds double-stranded DNA with a high-affinity intercalation between GC base pairs.

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