UHPLC and HPLC Products & Reviews

High purity solvents for LC-MS and trace analysis with UV and fluorescence detection: 0.2 µm stainless steel filtered – perfect for use in UPLC and UHPLC. Very high UV-transmittance. Excellent baseline stability in gradient elution. Very low total ionic current (TIC) in LC-MS. Low level of ionic background and ion suppression. High ionization efficiency in all ionization methods (electrospray ionization/atmospher…

Amino Acid Analysis Columns

The Chromaster Analytical HPLC System from Hitachi has established new limits in Performance, Ease-of-Use, and Robustness. Innovative low-pressure gradient mode, “High Frequent Mode,” and Hitachi’s proprietary real-time feedback control system greatly suppress liquid pulsation resulting in unparalleled retention time and gradient reproducibility. The Hitachi Chromaster is also available with 60 MPa maximum pressure.

Designed to meet the challenges of today's laboratory environment, fast results and demanding workload, LaChrom Elite® couples automated tasks with innovative design. Control by Empower™ 2 software facilitates regulatory compliance Features Innovation • System synchronization, Pump-Autosampler Synchronization (PASS) This unique feature means that each injection occurs at exactly the same point in every pump cycle ensuring the…

Hitachi's Ultra High-Speed Liquid Chromatograph, LaChromUltra,delivers ultra-fast analysis, higher resolution, increased sensitivity and the flexibility to run both conventional and ultra-high resolution LC analyses on a single system. LaChromUltra is the practical next generation LC solution that meets your laboratory's changing needs AND fits your budget Features • 60 MPa (8700 psi) pressure max and 2.0 µm particle size colu…

The Fused-Core ® particle technology behind Ascentis ® Express columns delivers maximum speed and efficiency on both HPLC and UHPLC systems. The novel superficially porous silica particles (SPP) are available in three different particle sizes and two different pore sizes for optimal suitability from micro over UHPLC and HPLC to semi-preparative use.

Monolithic silica-based Chromolith® HPLC columns allow rapid separations at very low column backpressure with high matrix tolerance and extended column lifetime, thus making them ideal products for high throughput and cost-efficient analyses of matrix-rich samples. 

The 1525 and 1525 with EF heads are integrated, high-pressure, binary HPLC pumps that feature on-board pulse dampening and efficient mixing. Their pulse-free solvent flow, from analytical to semi-preparative flow rates, makes them ideal for use with highly sensitive detectors. Designed for use with 2 to 4.6 mm I.D. columns in routine LC and LC/MS applications, these pumps have a programmable flow-rate range of 0.00 to 10.00 mL…

First generation Hybrid particles for high pH stability

An integrated HPLC system that works as hard as you do, available with push-button mass detection for the chromatographer. The Alliance™ HPLC System is the flexible and reliable workhorse that meets your fundamental HPLC separation requirements. The system has been continually expanded and perfected to accommodate an enormous range of real-world analytical challenges, culminating in today’s new industrial design which signi…

TURNING YOUR EVERYDAY CHALLENGES INTO COMPETITIVE ADVANTAGES. When Waters is part of your purification process, positive change happens. Suddenly, everything from sample prep and purity to recovery becomes a streamlined process you can’t live without. Because you’re moving your sample through the process faster, with better results, purification is no longer an obligation. It’s an asset. A complete line of flexible, workflow s…

Convergence Chromatography with the ACQUITY UPC² System Bring streamlined workflow, expanded selectivity, and an orthogonal technique to your laboratory. Convergence chromatography (CC) is a broad-based, complementary analytical platform that is taking its place alongside of LC and GC as one of the three essential separation technologies for modern laboratory analysis. This technique provides another, reliable choice as…

In 2004, Waters revolutionized liquid chromatography with the introduction of the ACQUITY UPLC System. At the heart of the system was Waters second generation hybrid, the Ethylene Bridged Hybrid (BEH) particle. In 2005, BEH Technology preparative particle sizes (2.5, 3.5, 5 and 10 μm) with the introduction of XBridge between HPLC and UPLC Technology platforms. BEH Technology particles offer: Excellent peak shape an…

HPLC and UHPLC method compatibility at the flip of a switch.

Extend your LC column lifetime while maintaining chromatographic performance.

UHPLC columns for unmatched selectivity choice

UV detection, optimized for UPLC/UHPLC separations.

A greener approach to high throughput purification

XBridge® and ACQUITY UPLC® Oligonucleotide C18 Columns for Synthetic Oligonucleotide Analysis and PurificationIon-pair, reversed-phase separation of detritylated oligonucleotides on sub-3 micron particles yields exceptional component resolution.UPLC ® technology increases sample throughput while maintaining necessary oligonucleotide component resolution.LC/UV and LC/MS methods for enhanced quantitative and qualitative oligonuc…

Waters ACQUITY UPLC - Dramatic Improvements in Speed, Sensitivity and Resolution Whether you work in methods development or quality assurance, in drug discovery and development or testing for safety in food supplies, you seek a productivity edge. With the ACQUITY UPLC® System, now you can get more information in a single, short run than you've ever seen with HPLC. Waters ACQUITY UPLC System UltraPerformance LC® (UPLC®) techn…

Excellent low pH stability and high mass loading capability

XBridge Columns include a selection of 10 general-purpose and application-specific sorbents that cover a wide range of particles sizes for analytical and preparative HPLC applications.   XBridge Column users can quickly develop robust methods using mobile phases throughout the entire pH range of 1-12. XBridge OBD™ Preparative Column users, benefit from high pH and temperature stability to provide increased mass loading f…

VanGuard Pre-Columns for UPLC® separations are guard columns that are designed for use with the ACQUITY UPLC® system. These guard columns use an ultra-low volume design (patent pending) that efficiently protects UPLC column performance. This ultra-low volume design does not compromise the UPLC holistic design approach to higher efficiency, greater resolution and increased throughput. Guard columns are typically used in appli…

Designed specifically for polymer characterization, the Styragel® columns are grouped into the HR series for low-to-mid molecular weight samples, the HT series for high-temperature applications, and the HMW series for high molecular weight samples. Specifically controlled styrene divinylbenzene formulations provide reproducible performance in your GPC applications.

Packed with hydroxylated polymethacrylate-based gel, Waters Ultrahydrogel™ SEC columns are ideal for the analysis of aqueous-soluble samples, such as oligomers; oligosaccharides; polysaccharides; and cationic, anionic, and amphoteric polymers. Measuring 7.8 mm x 300 mm, these high-resolution columns offer many advantages over conventional aqueous SEC columns, such as: - A wide pH range (2–12) - Compatibility with high concen…