UHPLC and HPLC Products & Reviews

100Å pore size, high ligand density;  available in 1.0, 2.0, 3.0, 4.0, 4.6 and 10 mm ids;  20 - 250 mm lengths. Pursuit columns are ideal for pharmaceutical applications using LC/MS, from analyzing lead compounds and biological samples in drug discovery, to implementing dependable analysis of raw materials and approved drugs in the QC process.  Build on the large 200A pore size silica, high liquid density delivers up to 40% fa…

High Throughput with Lowest Carryover      The Agilent 1290 Infinity LC Injector HTC/HTS is designed specifically to meet the throughput and reliability demands of critical LC/MS applications, offering lowest carryover with dynamic load and wash (DLW) principle. This highly versatile system is optimized for high throughput injections, and perfectly complements the infinitely better speed, resolution and sensitivity of the Agil…

The 1220 Infinity II LC is an integrated system for routine HPLC analysis in analytical and QA/QC labs. Based on the proven technology of the InfinityLab LC Series, the system's high quality and performance help you achieve maximum return on investment and lowest cost of ownership from day one.

ChromXP columns optimize performance, ease of use, and reliability of the SCIEX M5 MicroLC, MicroLC 200 Plus and NanoLC 400 systems. ChromXP columns ensure optimum separation and long term stability.  

The 1525 and 1525 with EF heads are integrated, high-pressure, binary HPLC pumps that feature on-board pulse dampening and efficient mixing. Their pulse-free solvent flow, from analytical to semi-preparative flow rates, makes them ideal for use with highly sensitive detectors. Designed for use with 2 to 4.6 mm I.D. columns in routine LC and LC/MS applications, these pumps have a programmable flow-rate range of 0.00 to 10.00 mL…

Amino Acid Analysis Columns

First generation Hybrid particles for high pH stability

An integrated HPLC system that works as hard as you do, available with push-button mass detection for the chromatographer. The Alliance™ HPLC System is the flexible and reliable workhorse that meets your fundamental HPLC separation requirements. The system has been continually expanded and perfected to accommodate an enormous range of real-world analytical challenges, culminating in today’s new industrial design which signi…

TURNING YOUR EVERYDAY CHALLENGES INTO COMPETITIVE ADVANTAGES. When Waters is part of your purification process, positive change happens. Suddenly, everything from sample prep and purity to recovery becomes a streamlined process you can’t live without. Because you’re moving your sample through the process faster, with better results, purification is no longer an obligation. It’s an asset. A complete line of flexible, workflow s…

Convergence Chromatography with the ACQUITY UPC² System Bring streamlined workflow, expanded selectivity, and an orthogonal technique to your laboratory. Convergence chromatography (CC) is a broad-based, complementary analytical platform that is taking its place alongside of LC and GC as one of the three essential separation technologies for modern laboratory analysis. This technique provides another, reliable choice as…

In 2004, Waters revolutionized liquid chromatography with the introduction of the ACQUITY UPLC System. At the heart of the system was Waters second generation hybrid, the Ethylene Bridged Hybrid (BEH) particle. In 2005, BEH Technology preparative particle sizes (2.5, 3.5, 5 and 10 μm) with the introduction of XBridge between HPLC and UPLC Technology platforms. BEH Technology particles offer: Excellent peak shape an…

Silica-based columns are stable and efficient but unsuitable for alkaline analyses due to the silica matrix's weakness under high pH. InertSustain C18, with its novel surface-modified silica, overcomes this limitation. It retains Inertsil's benefits—low back pressure, superior inertness, high efficiency, consistent performance, and wide solvent compatibility—while enabling analyses over a broad pH range.

PRP-X600 is a superficially porous weak-base anion exchange support that separates DNA oligomers according to negative charge.

TSKgel Amide-80 and TSKgel NH2-100 HILIC columns from Tosoh Bioscience are first class columns when it comes to separations of hydrophilic compounds like peptides, carbohydrates, polar natural substances, amino acids, oligonucleotides, organic polar acids and bases, even proteins.

HPLC column

Widely considered the premium columns for analyzing biopolymers by GFC, TSKgel G2000SWXL, 5 μm columns are an excellent choice for small proteins and peptide separations.

The TSKgel Alpha-4000 column is packed with rigid, porous polymer beads which show minimal shrinkage or swelling in polar organic solvents (methanol, acetonitrile, DMSO, isopropanol, THF, and HFIP). This column is stable in a wide variety of organic solvents at concentrations up to 100%.

The TSKgel OligoDNA RP and TSKgel TMS-250 columns incorporate 5 μm or 10 μm spherical porous silica with 250Å pores to allow unhindered access by large oligonucleotides and proteins respectively.

TSKgel STAT columns were designed to increase throughput for high efficiency separations of biomolecules. The nonporous, hydrophilic base material provides superior performance at reduced analysis time.

ZIC®-HILIC HPLC columns for the separation of all classes of polar and hydrophilic compounds. What is HILIC? HILIC or Hydrophilic Interaction Liquid Chromatography is a straightforward chromatographic technique for separation of many types of polar and hydrophilic compounds. To put it simple one can say that HILIC is a normal-phase (NPLC) type of separation but uses reversed-phase (RPLC) type eluents. In HILIC one has: A c…

The base silica of Purospher® STAR columns is 99.999 % pure. Furthermore, meticulous care is given to quality control over all aspects of silica structure and chemistry. The excellent converge of the surface and the purity of the material ensures excellent peak symmetry for acidic, basic and even for chelating compounds. Accurate results with excellent peak shape for all types of analytes Outstanding resolution due…

High purity solvents for LC-MS and trace analysis with UV and fluorescence detection: 0.2 µm stainless steel filtered – perfect for use in UPLC and UHPLC. Very high UV-transmittance. Excellent baseline stability in gradient elution. Very low total ionic current (TIC) in LC-MS. Low level of ionic background and ion suppression. High ionization efficiency in all ionization methods (electrospray ionization/atmospher…

The world’s most advanced multi-detector GPC/SEC system

With mid-size capacity and throughput, the VERITY 271 HPLC systems provide hundreds of configurations for semi-preparative and preparative purifications.

The Chromaster Analytical HPLC System from Hitachi has established new limits in Performance, Ease-of-Use, and Robustness. Innovative low-pressure gradient mode, “High Frequent Mode,” and Hitachi’s proprietary real-time feedback control system greatly suppress liquid pulsation resulting in unparalleled retention time and gradient reproducibility. The Hitachi Chromaster is also available with 60 MPa maximum pressure.