Scale-up Products & Reviews

Reaction and process understanding with real-time in situ analysis.

YMC HT Glass Columns are specially designed to accommodate the stringent requirements of high-temperature liquid chromatography applications. Capable of performing efficiently at temperatures up to 70 °C, these columns are perfectly suited for a broad spectrum of purification tasks, particularly in biochemical liquid chromatography (BioLC), where high temperatures are pivotal.

3M™ Harvest RC Centrate Chromatographic Clarifier is a single stage single-use chromatographic clarification solution designed to effectively clarify modern cell culture centrates. Centrate clarification using 3M™ Harvest RC Centrate Chromatographic Clarifier may provide many benefits including process compression, high product recovery, and improved process economics.

The 3M™ Harvest RC Chromatographic Clarifier is a single stage single-use chromatographic clarification solution designed as an efficient option for harvesting and clarification of modern cell cultures. Clarification using 3M™ Harvest RC Chromatographic Clarifier may provide many benefits including fewer processing steps, higher yield and lower production time and costs.

A breakthrough in process analytical technology for production of nanoparticles, biopharmaceuticals and polymers

The Celsius ® S3 Benchtop System is a laboratory instrument made to evaluate freeze & thaw processes of new drug candidates in single-use bags with full scalability to production-scale Celsius ® platforms (FFT, FFTp and CFT).

The XcytoMatic® 40 (XM40™) is a high-throughput cell density and viability analyzer that can run 24 samples in under 14 minutes. The variation between cell counts for these samples is under 3%. If scale-out and scale-up is a concern, you can trust each XM40™ instrument in your production to deliver the same quality results. The instrument-to-instrument variation for this model lies under 5%, supporting easy tech transfer. W…

Twin-screw extruders are well-established and used in a wide variety of food, polymer, and pharmaceutical applications to efficiently develop and produce high-quality products using a continuous process.  The modularity of the Thermo Scientific™ Process 11 Twin-screw extrusion equipment provides great flexibility in designing a process to accomplish your food process development goals.

Rapidly develop pharmaceutical formulations and adopt continuous processing methods using the Pharma 16 Twin-Screw Extruder. It can switch between continuous hot melt extrusion (HME) or wet granulation (TSG) with ease. Optimize drug process development parameters with less time and effort than batch processes and easily scale-up to larger Thermo Scientific extruders using minimal amounts of expensive APIs and excipients. 

Developed with real world experience and customer feedback at the forefront of the design, the SNAP ® laboratory column range provides effective hardware solutions for liquid preparative chromatography.