UHPLC and HPLC Products & Reviews

The 1260 Infinity II Bio-Inert Fraction Collector is the ideal extension to your system when you need to further investigate separated compounds. A wide range of collection vessels, including vials, microplates, or custom vessels, provide highest collection flexibility. Handling flow rates up to 10 mL/min, even separations using columns with larger inside diameters for small-scale preparative applications are possible.

The 1260 Infinity II Preparative Valve-Based Fraction Collector is a compact, full-featured fraction collector for daily compound isolation and purification by LC. Optimized for collection of up to 11 high-volume fractions its versatile design allows operation in both routine sample purification workflows and recovery applications. The built-in fraction delay sensor allows precise and automatic calibration of the fraction coll…

The 1290 Infinity II Preparative Open-Bed Fraction Collector is our most versatile fraction collector, enabling high-capacity fraction collection of purified compounds for semipreparative and preparative-scale LC purification. This module is ideally suited to open-access environments, provides all standard trigger modes for purification workflows, and is optimized for flow rates up to 200 mL/min.

The 1290 Infinity III Multicolumn Thermostat (MCT) is a UHPLC column oven that provides precise temperature control over a broad temperature range with cooling to 20 degrees below ambient and heating up to 110 °C. The MCT's column compartment houses up to eight columns.

The 1290 Infinity II Preparative Column Compartment is a high-end support module for purification workflows. It provides sufficient capacity to store up to four analytical and six preparative columns supporting dimensions from 4.6 to 50 mm inner diameter and 50 to 250 mm length. Five multipurpose slots are available for mounting of valves, delay coils, and further auxiliary purification modules.

The 1260 Infinity III Multicolumn Thermostat (MCT) is a thermostatted HPLC column compartment that provides precise temperature control for up to four columns over a broad temperature range with cooling to 10 degrees below ambient and heating up to 85 °C.

The 1260 Infinity II Preparative Column Organizer is a support module for purification workflows. It provides convenient and stable mounting of a manual injector and easily organizes both analytical and preparative columns from 4.6 to 50 mm inner diameter.

The 1290 Infinity III Diode Array Detector FS (fixed slit) delivers multiple wavelength detection with full spectra at sampling rates up to 120 Hz for fast LC separations. The Max-Light cartridge cell features optofluidic waveguides, which improve light transmission to near 100% efficiency without sacrificing resolution caused by cell dispersions effects.

The 1290 Infinity III Variable Wavelength Detector enables highest productivity with fast analysis at up to 240 Hz data rates. Even more sample information can be acquired in dual-wavelength mode. Time-programmable wavelength switching provides optimum sensitivity and selectivity for your applications.

The 1260 Infinity III Diode Array Detector WR offers multiple wavelength and full spectral detection up to a 120 Hz sampling rate. Maximum flexibility is guaranteed with a wide wavelength range of 190 to 950 nm with dual-lamp design, as well as the choice of 15 analytical, preparative, and SFC flow cells.

The 1260 Infinity III Evaporative Light Scattering Detector (ELSD), although targeted at analytical scale, can also be used with a flow splitter for preparative chromatography applications. It is highly recommended for compounds with little or no UV chromophore, since the detector technique evaporates the solvent and then measures the intensity of the scattered light, which is directly proportional to the sample concentration.

The 1260 Infinity II High-Temperature Evaporative Light Scattering Detector (HTELSD) is capable of detecting very low concentrations of high-molecular-weight polyolefins (polyethylene and polypropylene) at elevated temperatures. The need to analyze ultrahigh-molecular-weight polyethylene (UHMWPE) requires a new detection technique that offers a high level of baseline stability in order to reproducibly detect and permit accurat…

The 1260 Infinity III SFC Control Module is a carbon dioxide conditioning unit for supercritical fluid chromatography. This module pre- and postconditions CO2 for InfinityLab SFC solutions. CO2 preconditioning provides for unmatched stability and precision of retention times, and postconditioning enables trouble-free connection to mass spectrometers. 

The InfinityLab LC Companion acts as a mobile LC user interface to allow for remote control, monitoring, signal plotting, and diagnostics of Agilent 1260 and 1290 Infinity II LC systems. With the InfinityLab Companion, any mobile device - such as a tablet device or smartphone - with a compatible web browser can be turned into a mobile user interface to quickly check the status of your LC instrument.

Agilent Bio-Monolith Protein A LC columns are designed for analytical separation of most of  IgG subclasses (human and mouse). It delivers fast and accurate quantitation of mAb titer and purification of small amounts of mAb for further characterization. These monolithic column enables extremely fast separations to speed up method development time and decrease costs. They are compatible with HPLC and UHPLC systems.

The 1260 Infinity II Prime Online LC System is a process analysis system enabling automated process monitoring, providing real-time data for greater control and faster understanding of processes.

The 1260 Infinity II Online Sample Manager is an online sampling module that connects the analytical world with the process world. The module provides automated sample analysis via direct injections or retained samples from flow reactors, batch reactors, as well as upstream bioreactors and downstream purification devices.

The 1260 Infinity III Prime Bio LC System is a versatile HPLC instrument for bioseparations and offers outstanding functionality and operational convenience for biochromatography, and entry-level quaternary bio UHPLC at pressures up to 800 bar and flow rates up to 5 mL/min.

The 1290 Infinity II Bio High-Speed Pump is a binary UHPLC pump consisting of biocompatible material for use in biopharma and other applications utilizing high salt and extreme pH conditions. It uses high-pressure blending from up to two solvents at pressures up to 1300 bar and flow rates up to 5 mL/min.

The 1260 Infinity III Bio Flexible Pump is a UHPLC pump comprising biocompatible components, developed for biopharma applications and for other analyses requiring high-salt and extreme-pH conditions. This pump enables quaternary solvent delivery at pressures up to 800 bar and flow rates up to 5 mL/min.

The 1290 Infinity II Bio Multisampler, with its biocompatible sample flow path, is perfectly suited for biomolecule analysis, ensuring integrity of biomolecules and minimizing unwanted surface interaction. For temperature-sensitive samples, a compressor-based thermostatting device can be added.

AdvanceBio Peptide Plus columns are reversed phase, superficially porous particle LC columns optimized for the separation of target peptides, impurities, and post translational modifications.

The 1260 Infinity III Prime Analytical-Scale LC Purification System is a versatile preparative high-performance liquid chromatography (HPLC) instrument. This system offers the highest functionality and operational convenience for analytical-scale HPLC purification and entry-level quaternary UHPLC at pressures up to 800 bar and for flow rates up to 5 mL/min.

The 1260 Infinity III Prime Bio Analytical-Scale LC Purification System is a versatile preparative high-/ultrahigh-perfomance liquid chromatography (HPLC/UHPLC) system for bioseparations. The system offers outstanding functionality and operational convenience for bioanalytical HPLC and entry-level quaternary bio UHPLC at pressures up to 800 bar and flow rates up to 5 mL/min.

The 1260 Infinity III Bio-Inert Analytical-Scale LC Purification System is a dedicated solution for purifying large biomolecules in biological samples, including monoclonal antibodies and proteins.