UHPLC and HPLC Products & Reviews

Bringing You Closer to Universal DetectionWhen carrying out chromatographic runs, do you require any of the following? •Need confidence that you have seen all the peaks in your separation •Require unattended, reproducible operation •Collect fractions that do not have chromophores for UV/Vis triggering With Waters new 2420 ELSD, you’ll get the answers you’re looking for faster. And, the Waters 2420 ELSD is the smallest ELSD on…

eXtended Performance [XP] 2.5 µm Columns are high efficiency, low backpressure HPLC columns that can be easily utilized across all HPLC, UHPLC and UPLC Technology platforms. Low Backpressure. High Throughput. Improved Productivity. • 40% lower backpressure than sub-2-µm UPLC columns • Increase flow rate to increase throughput • Equivalent backpressure and superior performance to core-shell columns • Improve HPLC productivity 2…

The 1.7 µm Ethylene Bridged Hybrid [BEH] particle is one of the key enablers behind UPLC® technology.It is available in three different pore sizes [130Å, 200Å and 300Å] and several bonded phases for reversed-phase and hydrophilic interaction chromatography and is applicable from small molecule to large biopharmaceutical analysis. Due to the intrinsic chemical stability of hybrid particle technology, a wider usable pH range [pH…

The Waters Biopharmaceutical Platform Solution with UNIFI® integrates robust UPLC®/MS characterization technology with the UNIFI Scientific Information System for applications in bioseparations, intact protein mass analysis, peptide mapping and released glycan analysis.This platform unites all aspects of biotherapeutic analyses and workflows, enabling organizations to apply high resolution analytics across the development proc…

The µPorasil/Porasil column brand silica has 125A pore size with 325m2/g surface area. With a range of different particle size offerings, you have the option of scalability for preparative application with µPorasil column as a QC tool.

For high resolution separations of polar compounds

Released N-Glycan Columns

Released N-Glycan Columns

HILIC for Large Biomolecules

Reversed-Phase Peptide Columns

ACQUITY™ Arc™ MDLC Systems offer highly repeatable and accurate multi-dimensional HPLC separation performance for your complex samples.

Atlantis Premier BEH Z-HILIC Columns provide an increase in polar analyte retention and offer a different selectivity when compared to other HILIC chemistries, both powerful attributes when performing HILIC methods development.  Built using rugged ethylene bridged hybrid particles, these columns are pH stable from pH 2-10; the MaxPeak High Performance Surface hardware technology significantly reduces unwanted analyte/surface i…

Achieve ultimate sensitivity in the clinical laboratory. 

Glycan columns for the analysis of released N-labeled glycans using UPLC and with MaxPeak High Performance Surfaces to reduce non-specific adsorption.

Glycan columns for the analysis of released N-labeled glycans using HPLC and with MaxPeak High Performance Surfaces to reduce non-specific adsorption.

Anion exchange, reverse-phase columns that provide charged-based separations and extra resolution for acidic glycans. With MaxPeak High Performance surfaces that reduce non-specific adsorption.

These columns are been purposefully designed for intact glycoprotein profiling, subunit fragment analysis, and glycopeptide mapping using hydrophilic interaction chromatography (HILIC). 

Designed for reverse-phase separation of amino acids derivatized with AccQ•Tag Ultra reagent. Rapid separation with a superior resolution for HPLC/UHPLC. 

Separating the signal from the noise. PFAS Solution Installation Kits provide everything  you need to get your analytical system PFAS ready.  

Designed to meet the everyday challenges facing pharmaceutical quality control (QC) labs, the Alliance™ iS HPLC System delivers a new era of intuitive simplicity by reducing errors with innovative system intelligence, enhancing productivity with safeguards to ensure system performance, and maximizing system uptime. 

Accelerate early research, development, & release testing of GTx drug substances and products

Size-based separations of peptides, proteins, and viral vectors

Reversed-phase based separations of peptides

The VanGuard FIT column format utilizes a unique, easily replaceable Fully Integrated Technology (FIT) pre-column cartridge that avoids added dispersion and facilitaes easy method transfer of existing methods run on standard columns.  

High Resolution 5 µm particle for Anion-exchange SAX) HPLC of nucleic acids