UHPLC and HPLC Products & Reviews

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High performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Stainless Steel Fittings

IDEX Health & Science

  Stainless steel fittings remain the most popular fitting used on standard HPLC systems today, due to their high temperature resistance and high-pressure holding abilities. Our durable and strong 316 Stainless Steel Fittings are rated to 20,000 psi (1,380 bar) when wrench tightened. You can choose our Standard Fittings, or select from other manufacturer-compatible offerings.  

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Actuated Valves for UHPLC

IDEX Health & Science

MX Series II™ actuated valves are designed to be added to your existing instrument or to work optimally with stand-alone lab configurations. Our valves can be controlled remotely or operated manually using the push-button front panel with LED position indicator. They easily connect to your instrument or PC through contact closure, BCD, serial port, or USB. Commands can be sent to the MX valves using your chromatograph…

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UHPLC Fittings

IDEX Health & Science

We offer an innovative line of Very High Pressure (VHP) fittings, designed to withstand extreme pressures. This patent-pending line of ground-breaking fitting systems is perfect for use within the increasingly demanding requirements of today’s UHPLC high performance analytical systems.

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Raptor FluoroPhenyl LC Column

Restek Corp.

Restek's Raptor FluoroPhenyl column offers the ability to run in reversed-phase or HILIC mode for a variety of compounds. It is ideal for increasing sensitivity and sensitivity in LC-MS analyses. 

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Ascentis® Express Biphenyl, 2.7 μm, HPLC Columns

Sigma-Aldrich Supelco

The Ascentis Express biphenyl phase chemistry offers alternative selectivity for pharmaceutical analytes and drug metabolites that are not well retained or difficult to resolve on traditional alkyl (C18) and phenyl bonded phases. Ascentis Express HPLC columns, through the use of Fused-Core® particle technology, can provide you with both the high speed and high efficiencies of sub-2 ?m particles while maintaining lower backp…

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Lux AMP Chiral Columns

Phenomenex Inc

Chiral analysis of amphetamine and substituted amphetamines Lux 3 µm AMP is a unique LC media with pH stability from 1-11.5 that was specifically developed for the chiral analysis of amphetamine and substituted amphetamines, including methamphetamine.

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Kinetex C8

Phenomenex Inc

Moderate hydrophobic and steric selectivity is offered, bringing ultra-high performance to USP L7 and other octyl silane methods.

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Thermo Scientific™ MAbPac™

Thermo Fisher Scientific

Use the new Thermo Scientific™ MAbPac™ RP columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins. These columns have excellent resolution, long column lifetime, and low carry-over.

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SecurityCAP LC Solvent Safety Products

Phenomenex Inc

The SecurityCAP™ mobile phase and solvent waste safety caps prevent dangerous vapors and gases from leaving HPLC/ UHPLC solvent reservoirs. Over time, these chemicals can have a negative impact on the health of all employees and visitors in the lab. When lab safety and dependable results are a priority, you need SecurityCAPs.

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Luna Omega PS C18

Phenomenex Inc

Unique, 100 % aqueous stable mixed-mode phase that provides both polar and non-polar retention. The surface contains a positive charged ligand which aids in the retention of acidic compounds through ionic interactions, while the C18 ligand promotes general reversed phase retention. The positively charged surface also improves basic compound peaks shape through ionic repulsion. Available in: 1.6µm, 3µm, and 5µm

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