UHPLC and HPLC Products & Reviews

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High performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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AZURA® SMB

KNAUER Wissenschaftliche Geräte GmbH

From KNAUER, Simulated Moving Bed  - The Next Step in Chromatography! Preparative chromatography (Simulated Moving Bed) is increasingly applied as a separation technique in the pharmaceutical industry, production of fine chemicals, and in the field of bioengineering. Why Simulated Moving Bed? Simulated Moving Bed is a method in process chromatography that enables substance mixtures to be continuously separated and extracted in…

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Guard Cartridge Holders

Thermo Fisher Scientific

The Direct Connection UNIGUARD allows the guard cartridge outlet to be directly placed against the analytical column inlet frit. Product detail: We recommend all analytical columns are protected by a guard cartridge, which is replaced on a regular basis. The ID of the analytical column determines the correct ID for the guard cartridge. We offer 10x1, 10x2, 10x3, 10x4mm guard cartridges in all our stationary phases to ensur…

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Javelin Guard Columns

Thermo Fisher Scientific

The Javelin guard design is a one-piece format that can be installed without wrenches and requires no holder, which allows quick and easy replacement. Product detail: We recommend all analytical columns are protected by a guard column or cartridge, which is replaced on a regular basis. The ID of the analytical column determines the correct ID for the guard, so we offer 1.0, 2.1, 3.0 and 4.0 diameter Javelin guard columns in…

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HyperREZ™ Polymeric Carbohydrate Columns

Thermo Fisher Scientific

HyperREZ™ columns are specially designed for analysis of organic acids, alcohols, saccharides and carbohydrates. They employ a polymeric support with ligand exchange groups. The ligand exchange resins contain highly sulfonated cation exchange resins that have Group I, Group II or transition metals associated with the chromatographic surface.HyperREZ™ columns are based upon a polymeric resin that shows stability from pH 1 to 14…

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BioBasic 8/4/AX/SCX/18 Columns

Thermo Fisher Scientific

BioBasic 8 Columnso   Improved reproducibility, efficiency and column lifetimeso   Range of stationary phases to optimize selectivityo   Powerful resolution, even on short column lengths Product detail:BioBasic 8 columns provide exceptional reliability for separations of proteins, peptides, and other biomolecules through a combination of high purity silica and reproducible, stable bonding.  The proprietary bonding procedure en…

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BetaMax Acid/Neutral/Base Columns

Thermo Fisher Scientific

BetaMax Acid Columns o   High surface area area and bonded phase coverage for maximum retention, even in high percentage organic conditionso   Chemistries for acidic compounds Product detail: For alternative selectivity to traditional alkyl phases, we recommend you try the polar embedded phase BetaMax columns. The stationary phase contains urea groups embedded within the C12 chain, which extra interactions with samples to…

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BETASIL C18/C6/D101/C1/CN Columns

Thermo Fisher Scientific

BETASIL C18 Columnso   Broad range of particle sizes and phases for wide method development optionso   High surface area and phase coverage for reproducibility and sharp peak shapes Product Detail BETASIL columns are based on 100Å pore size, fully deactivated type B silica to ensure sharp peaks and excellent reproducibility for the analysis of a wide range of compounds. The 100Å pore size gives a higher concentration of statio…

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BetaBasic 4/8/18 Columns

Thermo Fisher Scientific

BetaBasic 4 Columnso   Excellent peak shapes for basic compoundso   Superb stability at both low and high pH Product detail:BetaBasic 4 columns are based on a 150Å pore size, fully deactivated type B pure silica to ensure sharp peaks and excellent reproducibility for the analysis of basic compounds.  Due to stable bonding chemistry and excellent surface coverage, BetaBasic 4 columns show excellent peak shape for basic compound…

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Hypercarb Columns

Thermo Fisher Scientific

o   100% porous graphitic carbon with very different selectivity to reversed-phase silica columnso   Exceptional retention of very polar compoundso   Separation of structurally similar compoundso   Stable from pH 1 to 14 at high temperatures in a wide range of solvents Product detail: Hypercarb is a unique material for HPLC manufactured by Thermo Hypersil-Keystone. Hypercarb consists of fully porous spherical carbon particle…

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Hypersil Duet C18/SCX Columns

Thermo Fisher Scientific

o  Separate hydrophobic and ionic compounds in a single runo  Select from two mixed mode phases, using either cation or anion exchange combined with C18o  Retention of compounds is optimized using mobile phase pH, ionic strength and percent organic Product detail: Hypersil Duet columns are an ideal choice for unknown compounds and metabolism studies, as they can separate hydrophobic and ionic compounds in a single analysis…

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Hypersil SAX Columns

Thermo Fisher Scientific

The Hypersil SAX is recommended for analysis of small organic molecules and organic acids. Product detail: Hypersil SAX is a strong anion exchange column, which is typically used for  analysis of small organic molecules and organic acids. As the columns are based on the first generation classical 120Å pore size silica they are not recommended for analysis of biomolecules. For new methods we recommend trying our latest ion…

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Column Heater and Chiller Units From Thermo Electron

Thermo Fisher Scientific

Thermo Electron Hot and Cool Pockets™ offer unbeatable value in coulmn temperature control. The pockets are small and light weight yet offer precise temperature control. Hot pockerts heat from 5 to 85 oC with a temperature accuracy of ±2oC over the entir range, and a temperature stability of ±0.1Oc. Hot Pockets™ and Cool Pockets™ are not available within the European Union at the present time. We apologise for any inconvenien…

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8-SC(B)

Chromacol Ltd

A new screw cap that has been introduced for HP users, to enable them to use a screw top vial on a robotic arm autosampler.

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ACQUITY UPLC® BEH Phenyl Columns

Waters

ACQUITY UPLC® BEH Phenyl columns utilize a trifunctional C6 alkyl tether between the phenyl ring and the silyl functionality. This ligand, combined with the same proprietary endcapping processes as the ACQUITY UPLC™ BEH C18 and C8 columns, provides ultra-low column bleed, long column lifetimes and excellent peak shape. This unique combination of ligand and endcap on the 1.7 μm BEH particle creates a new dimension in selectivi…

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