Assay Assembly Reagents Products & Reviews

A novel thermoreversible gel mountant for temporary immobilization and imaging.

An orange probe staining both nucleus and cytoplasm.

A novel thermoreversible gel mountant for extended immobilization and imaging.

Functional cell-based assays provide more physiologically useful information compared to binding and non-cellular assays. ChanTest offers cell-based assays to over 90 ion channel targets for screening and profiling for both early discovery and safety liability assessment. Both replicating and division-arrested cell lines are available for most targets which have been validated on a variety of automated electrophysiology plat…

Imaging probes conjugated to IRDye 800CW and IRDye 700DX have propelled more than 20 Phase I and Phase II clinical trials worldwide.

Roche FuGENE HD Transfection Reagent is a next-generation transfection reagent, free of animal-derived components. Roche FuGENE HD Transfection Reagent is designed to transfect a wide range of eukaryotic cells, including insect cells and many tumor cell lines not transfected well by other reagents (e.g., MCF7, Hep G2, PC-3, HeLa, MA-10, Hep G2, SH-SY5Y, A7r5, STO, SCC-61, SQ20B, T98G, STSAR-90, A375, A549, and others). In addi…

Roche FuGENE 6 Transfection Reagent is a non-liposomal multicomponent reagent well-suited for experiments involving cellular analysis. Due to the simple methodology of FuGENE 6 Transfection Reagent, minimal optimization, low cytotoxicity, and ability to provide high transfection efficiency even in the presence of serum, it is one of the standard transfection reagents in many different laboratories around the world. With a ment…

Chemical Name: (RS)-3,5-Dihydroxyphenylglycine Selective group I metabotropic glutamate receptor agonist which activates both mGlu1 and mGlu5. Also reported to be an antagonist at metabotropic glutamate receptors linked to phospholipase D. Selective group I mGlu agonist.

Sino Biological has successfully developed anti-payload antibodies with high purity, specificity, and affinity, which are used for analyzing the plasma/serum PK profiles, DAR values, and drug load distribution of ADC drugs.

IRDye 680RD is the near-infrared fluorescent dye of choice for applications in the 700 nm wavelength, especially Western blots, cell-based assays such as the In-Cell Western assay, and small animal imaging experiments.

IRDye Infrared Dyes and near-infrared (NIR) fluorescent imaging deliver enhanced sensitivity due to low background autofluorescence in the near-infrared region, therefore, giving a higher signal to noise ratios.

IRDye 680LT dye is highly soluble in water and is significantly brighter and more photostable than many other 700 nm near-infrared dyes.

The Venom Discovery Array (VDA) is a naturally compressed, hit-to-tool screening library based on a 96-well automation compatible array. These VDA's can be customised to meet target specific needs, such as the 48 phylogenetically diverse tarantula species to target ion channels or snakes for cancer research amonst others.For further information please click on the company website link.

Reduce labor costs by using our ready-to-use Lateral Flow Coupling Kit for magnetic and latex particles. No messy pre-preparation of reagents required. Simply pipette Anteo's water-based Activation Reagent onto your chosen particles to activate. Hands-on time for surface activation and coupling is 60 minutes. Magnetic particles are easier to use than gold. Magnetic separation removes the need to perform centrifugation and f…

Anteo’s ready-to-use Antibody Coupling Kit for magnetic, polystyrene and silica particles is a less hazardous alternative to covalent NHS/EDC chemistry. No messy pre-preparation of reagents required. Simply pipette Anteo's water-based Activation Reagent onto your chosen particles to activate. Hands-on time for surface activation and coupling is 60 minutes.                   With this kit, antibodies assemble in the correct…

Reduce labor costs by using our ready-to-use Magnetic Separation Coupling Kit. No messy pre-preparation of reagents required. Simply pipette Anteo's water-based Activation Reagent onto your chosen particle to activate. Hands-on time for surface activation and coupling is 60 minutes. This kit greatly reduces the risk of antibody damage, leading to less antibodies required for the experiment, increased antibody functionality,…

X-tremeGENE siRNA Transfection Reagent efficiently delivers short interfering RNA (siRNA) into many commonly used cell types including HeLa, NIH 3T3, HEK-293, CHO-K1, and COS-7, and several hard-to-transfect cell lines such as HT29, a human adenocarcinoma cell line. When used for cotransfection-based gene knockdown, X-tremeGENE siRNA Transfection Reagent enables significant protein expression and effective knockdown levels due…

Use G-418 antibiotic to select and maintain eukaryotic cells that are stably transfected with the genes for neomycin resistance. High purity: Use less antibiotic and produce greater selection pressure while minimizing toxicity from contaminants. Convenient sterile-filtered liquid format: Reduce time, effort, and potential errors by using a prepared sterile-filtered solution instead of making stock solutions from powder.…

R&D Systems Recombinant SCF Protein Stem cell factor (SCF), also known as c-kit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28 - 40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. Specifications and Use for R&D SC…

SIRT1 belongs to the class III family of HDACs, which are NAD+ dependent enzymes. SIRT1 modulators have been shown to play a beneficial role in treating diseases such as cancer, diabetes, metabolic disease and inflammation, making them attractive targets for the development of new drugs. The new HTRF® SIRT1 assay, developed by Cisbio Bioassays using its patented HTRF technology, is a homogeneous method for directly measuring S…

G-Protein Coupled Receptors (GPCRs) are common drug targets. Previously, most studies were based on the monomeric model, but this perception of GPCRs is now evolving towards homodimeric , heterodimeric and oligomeric models. To facilitate research into GPCR dimers, CisBio Bioassays has applied the Tag-lite® technology to GPCR interaction assays. Based on HTRF® technology, plasmids have been designed to express either the SNA…

Cisbio Bioassays offer a comprehensive cellular platform to develop HTRF® ligand binding assays.Features: • Single technology and cellular platform for all GPCR assays • Unique non-radioactive ligand binding assays • Miniaturization down to < 10µl • Peptidic and non-peptidic fluorescent ligands • High Specific Binding • Low Non-Specific Binding with HTRF technology Tag-lite fluorescent ligands available for (Feb10): Vasopre…

Tag-lite® cell-lines and reagents, a multimodal environment streamlined for GPCR studies. Cellular trans-membrane receptors are high potential therapeutic targets in pharmacological research, among them G-Protein Coupled Receptors (GPCRs). To reach a better physiological understanding, their study is deepening and is now focusing on structural assessments (ligand binding, dimerisation) and also on multiple signal pathway assa…