ACQUITY UPLC M-Class System
The analysis you’ve always desired for nano- to microscale separations The ACQUITY UPLC M-Class System delivers the most robust, reliable, and highest quality nano- to microscale UPLC separations to every laboratory performing LC/MS analyses. With unprecedented usability, the ACQUITY UPLC M-Class System enables laboratories to succeed in analyzing compounds that are severely limited in amount or availability, even amid a comp…
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Great instrument for commercial purpose, reduced solvent consumption.
Sample analysis for quality control analysis
The Waters ACQUITY UPLC M-Class System is an ideal instrument for the pharmaceutical industry. It is ideal for routine quality control analysis of raw materials and finished dosage forms in the industry. This instrument is also useful for finding impurities in samples which is helpful for quality control analyst to approve or pass new raw material from various vendors with integrity and confidence.
Review Date: 12 Apr 2021 | Waters
Ideal instrument for metabolites.
Analysis of metabolites in tissues and cells
The Waters UPLC is good for metabolite studies. You can use the software Metabolyx, UNIFI or you can change the RAW file to NET CDF and analyze using the Thermo compound discover.
Review Date: 28 Jul 2020 | Waters
Useful partner in my laboratory.
Identification and assay
Very useful product that can give consistent results in identification, assaying and separations.
Review Date: 18 Feb 2019 | Waters
Reliable workhorse for proteomics applications
Peptide separation for proteomics applications
The Waters ACQUITY UPLC System was used in the lab for both off-line (connected to a MALDI spotter) and on-line (connected to an ESI instrument) separation of peptides. Great performance, reliable and easy to maintain. The maintenance steps most frequently used are shown in step-by-step videos on the Waters homepage. Good diagnostic tools for leak identification.
Review Date: 3 Mar 2017 | Waters
proteins and glycans
Waters Acquity UPLC MS instrument is very powerful and easy to use tool to study structure of high level of complexity. The instrument is sensitive and reliable.
Review Date: 2 Nov 2015 | Waters
The analysis you’ve always desired for nano- to microscale separations
The ACQUITY UPLC M-Class System delivers the most robust, reliable, and highest quality nano- to microscale UPLC separations to every laboratory performing LC/MS analyses. With unprecedented usability, the ACQUITY UPLC M-Class System enables laboratories to succeed in analyzing compounds that are severely limited in amount or availability, even amid a complex matrix over several orders of magnitude. Confidently achieve your laboratory goals with high-efficiency ACQUITY UPLC M-Class Columns ranging from 75 µm to 1 mm I.D. by using complementary mass spectrometry to support our full range of column I.D.’s, or run 300 µm to 1 mm I.D. columns with optical detection.
The system also offers a range of flexible configurations for HDX technology, UV detection, and 2D analysis.
ACQUITY UPLC M-Class System Features:
- Highest sensitivity - UPLC separations yield increased analyte concentration for higher UV and MS signal responses
- Maximum chromatographic resolution - New 15k psi-capable ACQUITY UPLC M-Class Columns deliver sub-2-µm particle performance
- Faster nano- and microscale separations - Increased operating pressures yield maximum flexibility for higher throughput analyses
- Higher resolution with longer columns - Increased pressure enables more separation power
- Confidence in sample analysis - New non-reactive wetted surfaces throughout the fluidic path minimize absorptive losses
- Increased solvent compataibility - Improved range of solvent blends precisely metered for gradient fidelity
- Increased sample capacity - Sample organizer compatibility allows you to store a wide variety of plates and vials in the system for longer, unattended operation
- UV compatibility - UV flow cells compatible with 300 µm to 1.0 mm I.D. columns to augment your UPLC/MS analysis
- Scalability - With flow rates from 200 nl/min to 100 µL/min, achieve the best chromatographic performance, from 75 µm to 1.0 mm I.D. columns covering a 170-fold range of column sizes
- Increased flexiblity - More value configurations enable a variety of applications, icnreased throughput, and maximized peak capacity
