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RiboShield® RNase Inhibitor

PCR BiosystemsPB.30.23-01Available: Worldwide

RiboShield® RNase Inhibitor is a recombinant protein that blocks the activity of a wide range of ribonucleases to reliably protect your RNA from RNase digestion.

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The inhibitor is designed for use in RNA-sensitive applications such as RT-qPCR, cDNA synthesis and RNA sequencing, where the presence of even small amounts of RNase can be highly detrimental to RNA quality and experimental outcome. RiboShield® RNase Inhibitor is able to perform over a wide range of reaction conditions and can sustain inhibition of RNase A at temperatures up to 65 °C for at least 30 minutes. It can be used to block the activity of a wide range of ribonucleases, including eukaryotic RNases of the neutral type (RNases A, B and C). It does not inhibit RNases T1, T2, U1, U2, CL3, RNase I and H. The inhibitor does not hinder other enzymes such as reverse transcriptases, RNA polymerases or Taq DNA polymerase making it compatible with many enzymatic reactions involving RNA.

Features

  • Superior protection leading to better performance of RNA-sensitive applications
  • Inhibits eukaryotic RNases, including RNase A, B and C
  • Compatible with reverse transcriptases, RNA polymerases and Taq DNA polymerase
  • Stable up to 65 °C for at least 30 minutes
  • Ribonuclease and phosphatase free

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