Drug discovery > Lead Discovery Products & Reviews

High-throughput screening capability on one fast, configurable microplate reader

Microbial screening colony picker with sample tracking and plate handling

Apoptosis is a normal physiologic process which occurs during embryonic development as well as in maintenence of tissue homeostasis. The apoptotic program is characterized by certain morphologic features, including loss of plasma membrane asymmetry and attachment, condensation of the cytoplasm and nucleus, and internucleosomal cleavage of DNA. Loss of plasma membrane is one of the earliest features. In apoptotic cells, the mem…

Aptio® Automation combines intelligent technologies with Siemens Healthineers workflow expertise to deliver flexible solutions that advance your laboratory’s productivity. Accelerate processing and achieve consistent turnaround time using intelligent routing, single-sample flow, and primary tube sampling technologies.Improve utilization of lab resources through data-driven simulations, optimization modeling, and best practices…

Universal, HTS Kinase Screening Assays Use higher ATP concentrations: Linear response up to 500μM ATP. Use any kinase and kinase-substrate combination, including peptide, protein, lipid, and sugar substrates. Perform the assay without substrate modifications. Obtain reliable results: Z´-factor values routinely >0.7. Reduce false hits: Luminescence is much less susceptible to interference from library compounds t…

The QuantiFluor™ RNA System contains a fluorescent RNA-binding dye that enables sensitive quantitation of small amounts of RNA in solution. Detecting and quantitating small amounts of RNA is a very important step used in many biological applications, particularly in molecular biology techniques. These include measuring yields of in vitro transcribed RNA and measuring RNA concentrations before performing Northern blot anal…

This ready-to-use multimode detection system includes: high-performance luminescence, fluorescence, UV-Visible absorbance, BRET and FRET, two-color filtered luminescence and kinetic measurement capabilities.   The GloMax® Discover System is a high-performance multimode detection instrument developed with Promega reagent chemistries to provide a simple means of detecting advanced chemistries. This instrument provides…

The mass spectrometry-compatible yeast and human protein extracts are designed specifically for mass spectrometry applications.   The extracts are predigested and cleaned up by solid-phase extraction for immediate use in liquid chromatography/mass spectrometry (LC/MS) analysis. Both the yeast and human extracts also are available in an intact undigested form to provide a test material for optimizing mass spec protei…

The GloMax® Explorer System is the newest member of the GloMax® System detection instruments. This multimode reader allows you to get up and running quickly, generating the data you need from your experiments. Simply unpack it, plug it in, and begin your experiments.

Automated Nucleic Acid Purification with Integrated Quantitation

Easy-to-Use, Dedicated Microplate Developed and optimized with our cell and gene reporter assays

Ultrasensitive Single Tube Luminometer Two fluorescence modules available

A Complete Solution for Monitoring LC and MS Instrument Quality Control and Performance. In combination with an accompanying software tool, the 6 × 5 LC-MS/MS Peptide Reference Mix provides a convenient way to assess LC column performance and MS instrument parameters, including sensitivity and dynamic range. Consists of 30 peptides; 6 sets of 5 isotopologues of the same peptide sequence, differing only in the number o…

Measure Chymotrypsin-, Trypsin- and Caspase-Like Activities

The Caspase-Glo ® 3/7 Assay System is  a highly sensitive caspase activity assay for use in plate-reader assays.

NEW immunoGrade™, hydroGrade™, and lipoGrade™ BRANDplates® from BrandTech Scientific feature specially treated surfaces for use in a variety of immunological assays, such as ELISA, RIA, FIA and more. Available in a full range of well shapes and colors in 96-, 384-, and 1536-well formats. 96-well BRANDplates® immunoassay microplates feature blue alphanumeric embossing for easy well identification. immunoGrade™ — High Binding Ca…

Clean Screen® DAU Solid Phase Extraction Column is the flagship product of the forensic solid phase extraction column line. The first product of its kind in the industry, it is a mixed-mode column exhibiting both hydrophobic and cation exchange characteristics. Over 20 years of experience has shown this column to be effective on hundreds of drugs in both the acid-neutral and basic drug categories.

The Clean Screen® XCEL Solid Phase Extraction Columns are a line of sample prep phases designed to reduce the number of steps in the extraction, and therefore the amount of time and solvent necessary to complete the sample cleanup. Further advantages include reduced sample size and improved cleanliness and recovery. The Xcel I column will extract a wide array of basic drugs including benzodiazepines and opiates. The Xcel II co…

These cartridges are designed to meet large volume, real world samples. The frits and sorbent bed resist plugging, the format fits several types of manual and automated extraction systems. Various bonded phases available including C18, C8, DVB, & graphitized carbon black.

The Clean Screen® FASt column is a novel approach to improved sample preparation for LC/MS analysis. The column employs a one step process to prepare urine samples for analysis of multiple drugs and metabolites. By quickly and efficiently reducing the amount of unwanted matrix and particulates in the final sample, the analysis can proceed with less chance of matrix suppression and LC column clogging.

Clean Screen® Xcel Well Plates The Clean Screen Xcel products are a line of sample prep phases designed to reduce the number of steps in the extraction, and therefore the amount of time and solvent necessary to complete the sample cleanup. Further advantages include reduced sample size and improved cleanliness and recovery. The Xcel I well plate will extract a wide array of basic drugs including benzodiazepines and opiates.…

Positive Pressure Manifold - A simple, robust way to quickly process up to 48 samples at one time. The Positive Pressure Manifold can accommodate a multitude of column sizes and provides even flow to each position. Positive Pressure Manifold Features: All 48 positions are individually regulated to provide even pressure to each column. There are four banks of 12 positions each. The user can control flow to each of the four…

SELECTRA-SIL® Derivatizing Reagents SELECTRA-SIL® is an extensive line of derivatizing reagents manufactured by UCT at its facility in Bristol, PA. Our reagents are designed to increase molecular weight, lower boiling points, and create a more specific ion for compounds intended for gas chromatography and GC/MS. SELECTRA-SIL® Derivatizing Reagents Benefits: Improved chromatographic resolution - increased volatility - red…

Our 96 Deep Well Plates are made from solvent resistant, low extractable polypropylene. Standard frits are polyethylene with 20μm pores. The 2mL well provides capability for methods that require a larger sample size. The separate wells and greater capacity eliminate well-to-well carry over. We offer disposable plates compatible with Beckman, Caliper, Gilson, Hamilton, PerkinElmer and Tecan liquid handling systems. 96 Deep Wel…

Endcapped C18 - Enviro Clean SPE Cartridges Enviro-Clean® cartridges are designed for use by analysts that demand a clean, dependable and rugged product for low level environmental analyses. Our EC SPE Cartridges run the gambit of our sorbents for every configuration you require. C18, Octadecyl Hydrophobic, 1000 mg/6 mL. Part # EEC181M6