Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Invitrogen™ SYTOX AADvanced™ Ready Flow™ Reagent

Thermo Fisher Scientific

SYTOX AADvanced Ready Flow Reagent is a high-affinity nucleic acid stain for the detection of dead cells in flow cytometry. SYTOX AADvanced Ready Flow Reagent can only enter cells that have lost membrane intergrity (e.g., dead cells). Once inside, it can bind with nucleic acids, emitting a red fluorescence, which has an excitation/emission maxima of 546/647 nm. The SYTOX AADvanced Ready Flow Reagent dye is spectrally similar t…

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Invitrogen™ SYTOX™ Dead Cell Stain Sampler Kit

Thermo Fisher Scientific

SYTOX™ Dead Cell Stain Sampler Kit contains sample sizes of five nucleic acid stains to identify the most appropriate satin to work in multi-color experiments. Stains include: SYTOX Blue (for the 405 nm violet laser), SYTOX Green (for the 488 nm blue laser with green emission), SYTOX Orange (for the 532 nm green laser), SYTOX AADvanced (for the 488 nm blue laser with red emission), and SYTOX Red (for the 633/5 nm red laser).St…

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Invitrogen™ Annexin V Alexa Fluor™ 488 Ready Flow Conjugate 

Thermo Fisher Scientific

Annexin V Alexa Fluor 488 Ready Flow Conjugate is a bright, easy-to-use stain for apoptosis with high affinity for phosphatidylserine (PS), which becomes exposed on the outer leaflet of cells undergoing apoptosis. The Annexin V Alex Fluor 488 conjugate is excitable at 495 nm with an emission peak at 519 nm.FeaturesStable at room temperatureConvenient, ready-to-use format—no need to dilute, weigh, or pipetteCan be added directl…

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Invitrogen™ Annexin V Alexa Fluor™ 647 Ready Flow Conjugate

Thermo Fisher Scientific

Annexin V Alexa Fluor 647 Ready Flow Conjugate is a bright, easy-to-use stain for apoptosis with high affinity for phosphatidylserine (PS), which becomes exposed on the outer leaflet of cells undergoing apoptosis. The Annexin V Alex Fluor 647 conjugate is excitable at 650 nm with an emission peak at 665 nm.FeaturesStable at room temperatureConvenient, ready-to-use format—no need to dilute, weigh, or pipetteCan be added directl…

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Invitrogen™ Annexin V APC Ready Flow Conjugate

Thermo Fisher Scientific

Annexin V APC Ready Flow Conjugate is a bright, easy-to-use stain for apoptosis with high affinity for phosphatidylserine (PS), which becomes exposed on the outer leaflet of cells undergoing apoptosis. The Annexin V APC conjugate is excitable at 650 nm with an emission peak at 660 nm.FeaturesStable at room temperatureConvenient, ready-to-use format—no need to dilute, weigh, or pipetteCan be added directly to Ca2+-containing me…

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Invitrogen™ Annexin V Pacific Blue™ Ready Flow Conjugate

Thermo Fisher Scientific

Annexin V Pacific Blue Ready Flow Conjugate is a bright, easy-to-use stain for apoptosis with high affinity for phosphatidylserine (PS), which becomes exposed on the outer leaflet of cells undergoing apoptosis. The Annexin V Pacific Blue conjugate is excitable at 410 nm with an emission peak at 455 nm.FeaturesStable at room temperatureConvenient, ready-to-use format—no need to dilute, weigh, or pipetteCan be added directly to…

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PE/Cy7 Annexin V

BioLegend

Available in 25, 100 or 300 test packs. Annexin V (or Annexin A5) is a member of the annexin family of intracellular proteins that binds to phosphatidylserine (PS) in a calcium-dependent manner. PS is normally only found on the intracellular leaflet of the plasma membrane in healthy cells, but during early apoptosis, membrane asymmetry is lost and PS translocates to the external leaflet. Fluorochrome-labeled Annexin V can t…

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AAV5 Titration ELISA

PROGEN

Unique microtiter plate enzyme immunoassay for the quantitation of virions and assembled empty capsids of human Adeno-associated Virus 5. The capture-antibody detects a conformational epitope not present on unassembled capsid proteins. The ADK5a antibody is used as capture and detection antibody in the AAV5 Titration ELISA (PRAAV5). Academic discount available on request.

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AAV9 Titration ELISA

PROGEN

Unique microtiter plate enzyme immunoassay for the quantitation of intact AAV9 wt virions, AAV9 recombinant virions or assembled and intact empty capsids of human Adeno-associated Virus 9. The capture-antibody detects a conformational epitope not present on unassembled capsid proteins. The ADK9 antibody is used as capture and detection antibody in the AAV9 Titration ELISA (PRAAV9). Academic discount available on request.

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Phage Titration ELISA

PROGEN

Kit allows fast titration of M13 particles by immunological recognition of protein VIII. Contains standard M13 titrated by electron microscopical method.

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AAV1 Titration ELISA

PROGEN

Unique microtiter plate enzyme immunoassay for the quantitation of virions and assembled empty capsids of human Adeno-associated Virus 1. The capture-antibody detects a conformational epitope not present on unassembled capsid proteins.

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AAV6 Titration ELISA

PROGEN

Unique microtiter plate enzyme immunoassay for the quantitation of intact AAV6 wt virions, AAV6 recombinant virions or assembled and intact empty capsids of human Adeno-associated Virus 6. The capture-antibody detects a conformational epitope not present on unassembled capsid proteins.  

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Mosaic SampleBank™

Titian Software Limited

Titian Software's Mosaic SampleBank provides full inventory tracking, sample ordering and workflow management in one pre-configured package, which can be rapidly deployed on the cloud or on-premise. An extensive range of out-of-the-box integrations make it easy to monitor and manage liquid handlers, automated storage, weigh stations and other lab equipment.

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