Drug discovery > Target Discovery Products & Reviews

Live-cell analysis system

The SyncroPatch 384 is a revolutionary automated patch clamp system combining high quality electrophysiological data acquisition and analysis with state-of-the-art liquid handling. With 384 amplifier channels and a 384-pipetting head, up to 384 cells can be recorded in parallel, resulting in a throughput of up to 20,000 high-quality data points per day. 

Contractility under physiological conditions

Fast, accurate, and automated brightfield and fluorescent cell counting

Lux3 BR is a small brightfield live-cell imager, equipped with a high-quality 6.4 MP CMOS camera. It is designed to work inside a standard cell culture incubator without disturbing temperature, airflow, and optimum culture conditions. Detailed brightfield images can be captured using the new device. In both x- and y-direction, 2072 pixels combined with 1.45 mm field of view provide a resolution of 0.7 µm/pixel. 

High-throughput live-cell analysis system

The Omni FL is a fluorescence (green and red) and brightfield microscope designed to image live cells directly inside a cell culture incubator. The device can be used for continuous cell culture monitoring, as well as endpoint assays. Applications: cell viability, transfection efficiency, co-culture analysis, and more.

The Port-a-Patch is a miniaturized semi-automated patch clamp system supporting giga-seal recordings from one cell at a time. It offers fast and easy access to patch clamp data with only minimal training. Not only a powerful research tool but also ideal for educational purposes and quick tests of cells and ion channels.

The Patchliner is a fully automated patch clamp system which records from either 4 or 8 cells simultaneously. The HEKA EPC10 amplifiers, full control over the pipette speed, ability to change protocols on-the-fly and flexible add-ons for temperature control and dynamic clamp make this instrument the most versatile APC system on the market. 

PIPETMAX® is an automated pipetting solution for the efficient processing of high-throughput biological assays. It will help you to improve on the accuracy, reproducibility, and consistency among all samples processed. Unlike traditional automation platforms, PIPETMAX comes in a benchtop size that easily fits into any lab.

PLATEMASTER® is an easy-to-use, accurate solution for high-throughput manual pipetting of 96- and 384-well microplates. Two models are available: PLATEMASTER P20 for pipetting volumes from 0.5−20 µL and PLATEMASTER P220 for pipetting volumes from 2−220 µL.  Increase the Productivity of Your Workflows The PLATEMASTER’s 96-channel design greatly reduces the number of pipetting steps necessary to fill a microplate when compar…

Metrohm presents Combustion IC (CIC), a fully automated system for the simultaneous determination of halogens and sulfur in widely differing matrices. With CIC, unlike with alternative methods the concentrations of the different halogens can each be shown separately. Moreover, digestion by pyrolysis is superior to offline digestion methods with regard to sample throughput and precision and correctness of results. CIC is ideal…

Reliable Drop Setting: Reduce Costs + Increase Reproducibility The NT8 ® - Drop Setter/Crystallization Robot is a fast, nanoliter-volume liquid handler with drop dispensing capability, including setting drops for Lipidic Cubic Phase (LCP) experiments. The 8-tip head aspirates and dispenses drops from 10 nL to 1.5 μL.

The MANTIS automated liquid dispenser excels at accurate, low-volume dispensing in a wide variety of scientific workflows. The system is an easy and affordable solution to quickly increase the reproducibility and quality of your research as well as the throughput and efficiency of your laboratory. 

Build Crystallization Screens with Ease The FORMULATOR ® - Screen Builder is a next-generation liquid handler specifically designed for Protein Crystallography that uses patented microfluidic technology to dispense up to 34 different ingredients to design even the most complex optimization screens. A 96-nozzle dispensing chip can dispense any volume of any ingredient of any viscosity into any well.

The TEMPEST ®  is a high throughput, multiple reagent dispensing platform. With up-to 96 independently controllable dispensing nozzles it can be a plate-filling workhorse or a flexible assay-development partner, adapting to your needs on the fly. Used in a broad range of application areas such as cell-based and biochemical assays; molecular biology and NGS; as well as high-throughput screening.

Transform biomolecular interaction analysis with Alto™, the world’s first Digital SPR™ system, featuring zero maintenance and cartridge-based characterization from ultra-low sample volumes.

Elevate your 3D research with Gri3D ® , the ready-to-use microwell plate designed for highthroughput, reproducible organoid culture. Based on a standard 96-microtiter plate, each well contains an ultra-dense U-bottom microwell array patterned in a cell-repellent hydrogel. Organoids are robustly generated in microwells, where they grow in suspension-like conditions and are located in the same imaging plane. A pipetting port on…

The HoloMonitor ® live cell imaging system enables long-term non-invasive analysis of cell cultures within your standard incubator. Cell biologists worldwide use PHI’s label-free cell imager to automatically obtain accurate live-cell morphology, migration, and proliferation data as well as multi-well time-lapse videos, down to a single-cell level in real-time.

The HoloMonitor ® live cell imaging system enables long-term non-invasive analysis of cell cultures within your standard incubator. With the latest add-on fluorescence module, cell biologists benefit from minimizing light exposure and reducing photocytotoxicity when automatically obtaining accurate live-cell morphology, migration, proliferation data, and multi-well time-lapse videos down to a single-cell level in real-time.

Genizer Jacketed Liposome Extruder

The Genizer Online Extruder works with a high-pressure homogenizer to reduce the number of passes needed for optimal liposome size distribution and desired particle sizes. The homogenizer's diamond interaction chamber pre-treats the liposome sample to the nanoscale.

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BellBrook Labs Transcreener ® ADP 2 Kinase Assays

BellBrook Labs Transcreener ® AMP 2 /GMP 2 Phosphodiesterase Assays