Drug discovery > Target Discovery Products & Reviews

GLP-1 is secreted from gut endocrine cells in response to nutrient ingestion and plays multiple roles in metabolic homeostasis.

Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.

Sterivex filter units work with syringes, peristaltic pumps or pressure vessels. They eliminate the risk of contamination associated with decanting or pipetting.Sterivex units are designed to dispense into virtually any storage container. The devices are available with different outlet connectionsSterivex filter units can process volumes up to 1,000 mL or 2,000 mL, depending on the type of membrane used in the device. A choice…

The Steriflip filter unit is designed to work with standard 50 mL centrifuge tubes, which eliminates sample transfer. To filter, just attach the unit to a 50 mL centrifuge tube containing your sample, flip it over, and apply the vacuum. When finished, the filtrate collects in the attached 50 mL centrifuge tube.Steriflip Nylon Net filters are now available in 40, 60 and 100 µm pore sizes, making them ideal for stem cell, cardio…

The Stericap ™ PLUS Universal Bottle-Top Filter Device provides fast, large-volume filtration into any sized bottle.

With their vertical membrane design, Amicon Ultra 0.5 mL filters deliver great performance and lower spin timesConcentrates 500 µL down to 15 µLConcentration factor 25 x to 30 xHigh sample recovery (greater than 90% of dilute starting solution)Fast processing time - 10 to 30 minutesConsistent recoveries thanks to the reverse spin capabilityReverse spin capability provides consistent recoveries

4 mm syringe filter with a Hydrophilic PVDF membrane, for non-sterile filtration, has a 0.22 µm pore size used in fine particle removal from aqueous & mild organic solutions.

The MILLIPLEX® MAP Mouse Cytokine/Chemokine Magnetic Bead Panel II - Premixed 12 Plex, MCP2MG-73K-PX12is used for the simultaneous quantification of the following Mouse analytes: Epo, Exodus-2, Fractalkine, IL-16, IL-21, IL-22, IL-25, IL-28B, MCP-5, MIP-3α, MIP-3β, TARC

The MILLIPLEX® MAP Rat Cytokine/Chemokine Panel - Premixed 14 Plex is used for the simultaneous quantification of the following Rat analytes: IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12, IL-18, GM-CSF, GRO/KC, IFN-γ, MCP-1, TNF-α

Thermo Scientific Nunclon Vita is a unique energy-treated polystyrene surface that enables growth of most cell lines directly on the surface without using matrix coatings or feeder cells. Thermo Scientific Nunclon Vita is the latest addition to an exceptional portfolio of cell culture surface products, including the Thermo Scientific Nunclon Delta surface, and joins an extensive range of technologies and products for all basic…

A new paradigm in weighing advances the fusion process: TheAnt serves to automatically weigh the sample and dispense the flux with extreme precision, to an accuracy of one tenth of a milligram. Specially designed for: Laboratories with high sample throughput for analysis by XRF, AA and ICP Perfect manipulation with Claisse borate fluxes Distinguishing features: Automatic weighing of sample Automatic dispensing of…

Prepares : Glass disks for XRF analysis Solutions for AA and ICP analysis Processes : Cement, ceramic, slag, glass, silica, carbonates Mining and geological samples Sulfides Bauxites, fluorides Polymers, catalysts Pure metals, ferroalloys and other alloys Samples containing highly volatile elements Distinguishing features : Precise control of low and high fusion temperatures NO calibration, NO c…

An automated dissolution testing system using UV-Vis analysis     The Agilent Multicell UV Dissolution System is one of the most innovative and flexible tablet dissolution systems on the market. The system provides a fully integrated, automated dissolution testing system using the award-winning Cary 50 UV-Vis spectrophotometer, ensuring a highly efficient and rugged solution to online dissolution/UV-Vis analysis.

Purge and Trap (P&T) performs highly sensitive volatile organic compound (VOC) analysis with low carryover, allowing accurate and precise GC and GC/MS determination of VOCs in water, wastewater, soils, and sludges.

Three different strains that provide varying levels of expression control with T7 promoter-driven vectors, such as the pCAL and pET vectors.BL21 derivatives for tight expression control Express toxic proteins Use BL21, BL21-Gold or BL21-CodonPlus cells High-level protein expression Use for established expression constructs Economical alternative

Agilent’s market leading SureSelect platform provides a complete portfolio of catalog and custom products, providing the flexibility you need from discovery to follow-up studies. Agilent’s custom solutions allow you to target your regions of interest using our free web portal SureDesign. Custom solutions are available for DNA and RNA target enrichment.

4 mL capacity with round bottom Self-standing design Black graduations and larger marking spots for easier filling and sample identification Manufactured from polypropylene to withstand temperatures to -196°C Silicone washer for a secure seal Vials may be color coded with inserts (see Cat. No. 430499) Special base design allows vials to be locked into cryogenic rack and tray (Cat. No. 430525 or 431131) for single-hande…

A revolution in vial crimping and decapping   Agilents new ergonomic manual crimpers and decappers remove the pain and discomfort of wrist strain with a lightweight, tailored design. Weighing 25-30% less than predecessors and eliminating sore, pinched hands, the new design dramatically improves user experience. Extensively tested with Agilent vials for optimal fit, and color-coded for ease of use, this tool is a necessity for…

The Agilent Gas Clean Filter System delivers clean gases, reducing the risks of column damage, sensitivity loss, and instrument downtime. Inserting a Gas Clean Filter System in the gas line immediately before the instrument inlet greatly reduces the level of impurities, thus improving trace analysis. 

Sample filtration is critical to achieving optimal system performance. Agilent Captiva Premium Syringe Filters make the process faster than ever with the industry’s highest flow rates and loading capacities. In addition, Agilent sets the standard for LC/MS testing and certifying more syringe filters to be completely free of observed extractables than any other manufacturer. All Agilent Captiva Premium Syringe Filters are supp…

jetPRIME™ is a new versatile and powerful DNA and siRNA transfection reagent for day-to-day experiments. jetPRIME™ ensures high DNA transfection efficiency and excellent gene silencing in a variety of adherent cells and is ideal for DNA/siRNA co-transfection. jetPRIME™ is very gentle to cells since it requires low amounts of reagent and nucleic acid during transfection. Effective and nontoxic DNA and siRNA delivery is essentia…

Roche NimbleGen provides the most sensitive and specific DNA Methylation microarrays and services on the market. Methylated DNA regions are accurately mapped using a combination of affinity-based enrichment, such as Methylated DNA Immunoprecipitation (MeDIP) or the Methylated CpG Island Recovery Assay (MIRA), followed by microarray analysis. Roche NimbleGen offers several types of DNA Methylation arrays for a variety of organi…

Use the Millicell® EZ SLIDE to culture, fix, stain and view your cells all in one device. There’s no need to tediously move cover slips from your culture dish to a slide. Leave the wells intact to fix and stain and acquire data simply and quickly with Millicell EZ SLIDES. Features of the the Millicell® EZ SLIDE:  •  Breakable tabs for easy well removal   •  No tools required to remove wells from slide   •  No adhesive used to…

The TPP tissue culture flasks stand for high quality aspects. Advantages of the tissue culture flask: uniform even surface of the growth area crystal clear transparency stable, slip-free stacking of several flasks bilateral marking area accurate volume scale for optic control of the filling volume For optimum tissue growth, the growth area is opto-mechanical treated. This enhances cell adhesion and cell growth. T…

shRNAmir-GFP: Visualize RNAi Thermo Scientific GIPZ Lentiviral shRNAmir advantages: shRNAmir design for specificity and increased knockdown efficiency TurboGFP marks cells expressing shRNAmir Efficient low copy knockdown- Important for pooled screens Genome-wide human and mouse coverage Perform efficient RNAi in primary and non-dividing cells Guaranteed* knockdown Please note that the pGIPZ and pTRIPZ vectors a…