Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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EXP® Pre-Column Filters

Optimize Technologies, Inc.

The EXP® Pre-Column Filter is ideal for protecting small-particle UHPLC columns at extreme pressures. Such techniques analyze samples in the most demanding applications, which can decrease the life of these expensive columns. EXP® Pre-Column Filters help extend that life and protect your column investment without sacrificing performance. Free-Turn® architecture allows the user to change cartridges by hand without breaking flui…

4.7/5.0
|4 Reviews

OPTI-PAK® Trap Columns

Optimize Technologies, Inc.

The OPTI-PAK Trap Columns unique hardware design integrates a PEEK holder with an auto-adjusting stem which provides a fluid interface with any 10-32 standard injector port, and guarantees a zero-dead-volume connection despite variances in tube stop depth. A proprietary method of frit placement allows the packed stem to be positioned directly into the flow path, which eliminates all excess swept volume. Less swept volume trans…

5.0/5.0
|1 Review


TubeSpin Bioreactor

TPP Techno Plastic Products AG

TPP TubeSpin® Bioreactors have proven their advantages in large scale screening and optimization processes of suspension cells. The optimization of the parameters, important for the production up-scaling, can be evaluated with small amounts maximizing the number of parallel experiments at the same time. Features of the TubeSpin® Bioreactor 50 • Working volume 1-35ml • Conical form • 5 openings (A,B,C,D,E) of different size abo…

5.0/5.0
|1 Review

Echo® 525 Liquid Handler

Beckman Coulter Life Sciences

The Echo 525 platform, like the other Echo liquid handler models, is designed to use sound energy to transfer reagents. Unlike the other Echo models, the Echo 525 platform transfers at a larger volume increment (25 nL). This enables the more rapid transfer of aqueous reagents required in biochemical and genomics assays setup.

4.8/5.0
|4 Reviews

GFP-Trap®

Chromotek GmbH

GFP -Trap® - use your fluorescence fusion as tag for biochemical studies.Curiously GFP, the most widely used labeling tag in cell biology, is rarely used for biochemical analyses. This may be due in part to limited GFP antibody availability and specificity as well as co-eluted heavy and light antibody chains that interfere with subsequent analyses.Our GFP-Trap® is a high quality GFP-binding protein coupled to a monovalent matr…

5.0/5.0
|2 Reviews

Guava® easyCyte™

Luminex

Our microcapillary flow cytometry systems are simpler to operate than traditional sheath-fluid based instruments and are far easier to maintain. They utilize small sample volumes, generate minimal waste, and have lower operating costs. As a result, easyCyte™ Flow Cytometers are uniquely amenable to on-demand use in the laboratory environment and have helped many scientists achieve insightful cellular analysis since 1998.

4.9/5.0
|3 Reviews

NEBNext® Reagents for DNA Library Preparation

New England Biolabs Inc.

NEBNext® reagents are a series of highly pure reagents that facilitate library preparation of DNA or RNA for downstream applications such as next generation sequencing and expression library construction. Available in sets, master mixes and modules, these robust reagents undergo stringent quality controls and functional validation, ensuring maximum yield, convenience and value. Advantages of NEBNext Reagents for RNA Library Pr…

4.7/5.0
|4 Reviews





ThermoMixer®

Eppendorf

The new generation of Eppendorf ThermoMixer® and ThermoStat incubator raise sample preparation to the next level Ever since the launch of the company’s first performance-defining Mixer and the first Thermostat in 1964 Eppendorf has been at the forefront of mixing and temperature control technology for µL volumes. Thanks to Eppendorf’s continuous development, an exciting new generation of Temperature Control and Mixing Instrume…

4.5/5.0
|16 Reviews

Clean Screen® Xcel Well Plates

UCT, Inc.

Clean Screen® Xcel Well Plates The Clean Screen Xcel products are a line of sample prep phases designed to reduce the number of steps in the extraction, and therefore the amount of time and solvent necessary to complete the sample cleanup. Further advantages include reduced sample size and improved cleanliness and recovery. The Xcel I well plate will extract a wide array of basic drugs including benzodiazepines and opiates.…

5.0/5.0
|1 Review

Positive Pressure Manifold

UCT, Inc.

Positive Pressure Manifold - A simple, robust way to quickly process up to 48 samples at one time. The Positive Pressure Manifold can accommodate a multitude of column sizes and provides even flow to each position. Positive Pressure Manifold Features: All 48 positions are individually regulated to provide even pressure to each column. There are four banks of 12 positions each. The user can control flow to each of the four…

4.9/5.0
|3 Reviews

96 Deep Well Plates

UCT, Inc.

Our 96 Deep Well Plates are made from solvent resistant, low extractable polypropylene. Standard frits are polyethylene with 20μm pores. The 2mL well provides capability for methods that require a larger sample size. The separate wells and greater capacity eliminate well-to-well carry over. We offer disposable plates compatible with Beckman, Caliper, Gilson, Hamilton, PerkinElmer and Tecan liquid handling systems. 96 Deep Wel…

5.0/5.0
|1 Review

OsteoMAX-XF™ Differentiation Medium

Merck

EMD Millipore’s OsteoMAX-XF™ Differentiation Medium is specially formulated to readily differentiate human mesenchymal stem cells into the osteogenic lineage as assessed by alizarin red and alkaline phosphatase staining. This proprietary formulation was developed using Plasticell’s CombiCultTM, a patented, bead-based, combinatorial technology specially developed for discovery of novel stem cell differentiation protocols. The u…

5.0/5.0
|1 Review

MALDI-7090 TOF-TOF Mass Spectrometer

Shimadzu Corporation

The MALDI-7090TM is targeted for proteomics and tissue imaging. It combines Shimadzu’s extensive MALDI TOF-TOF mass spectrometry expertise with novel patented technology to provide ultimate performance in identification and structural characterization of biomolecules.   Offering unparalleled MS/MS resolution and excellent mass accuracy, Shimadzu’s new MALDI-7090 tandem mass spectrometer achieves a new level of MALDI…

4.9/5.0
|5 Reviews


Q5® Site-Directed Mutagenesis Kit

New England Biolabs Inc.

Q5® Site-Directed Mutagenesis Kit enables rapid, site-specific mutagenesis of double-stranded plasmid DNA in less than 2 hours. The kit utilizes the robust Q5 Hot Start High-Fidelity DNA Polymerase along with custom mutagenic primers to create insertions, deletions and substitutions in a wide variety of plasmids. After PCR, the amplified material is added directly to a unique Kinase-Ligase-DpnI (KLD) enzyme mix for rapid, roo…

4.8/5.0
|4 Reviews

TransIT-X2™ Dynamic Delivery System

Mirus Bio LLC

An innovative, polymeric system for efficient delivery of plasmid DNA and siRNA/miRNA. Experience the transfection breakthrough. Achieve superior transfections with an innovative polymeric system that efficiently delivers both DNA and RNA out of the endosome and into the cytoplasm overcoming a critical barrier to nucleic acid delivery.Head-to-head comparisons against the Lipofectamine® 2000 illustrate superior or equal lucife…

5.0/5.0
|2 Reviews

BRAHMS* PCT Immunoassays

Thermo Fisher Scientific

The Thermo Scientific* BRAHMS* PCT Immunoassays are immunofluorescent assays used to determine the concentration of PCT (procalcitonin) in human serum and plasma. The Thermo Scientific* BRAHMS* PCT Immunoassays are intended for use in conjunction with other laboratory findings and clinical assessments to aid in the risk assessment of critically ill patients on their first day of ICU admission for progression to severe sepsis…

4.7/5.0
|2 Reviews

NEBNext® DNA Library Prep Master Mix Set for Illumina®

New England Biolabs Inc.

The NEBNext® DNA Library Prep Master Mix Set for Illumina® contains enzymes and buffers in convenient master mix formulations that are ideally suited for sample preparation for next-generation sequencing, and for preparation of expression libraries. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expressi…

5.0/5.0
|1 Review

NEBNext® Ultra™ DNA Library Prep Kit for Illumina®

New England Biolabs Inc.

he NEBNext® Ultra™ DNA Library Prep Kit for Illumina contains enzymes and buffers that are ideal to convert a small amount of DNA input into indexed libraries for next-generation sequencing on the Illumina platform (Illumina, Inc). The workflow of NEBNext Ultra DNA Library Prep Kit for Illumina is very user-friendly and fast with minimal hands-on time.NEBNext® reagents are a series of highly pure reagents that facilitate samp…

4.7/5.0
|2 Reviews

NEBNext® dsDNA Fragmentase®

New England Biolabs Inc.

NEBNext® dsDNA Fragmentase® generates dsDNA breaks in a time-dependent manner to yield 100–800 bp DNA fragments depending on reaction time. NEBNext dsDNA Fragmentase contains two enzymes, one randomly generates nicks on dsDNA and the other recognizes the nicked site and cuts the opposite DNA strand across from the nick, producing dsDNA breaks. The resulting DNA fragments contain short overhangs, 5´-phosphates, and 3´-hydroxyl…

4.9/5.0
|2 Reviews