Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Quik Change Site-Directed Mutagenesis

Agilent Technologies

The original QuikChange Site-Directed Mutagenesis Kits eliminate the need for subcloning into M13-based bacteriophage vectors and for ss-DNA rescue. This makes site-directed mutagenesis studies simple and reliable since it allows oligo-mediated introduction of site-specific mutations into virtually any double-stranded plasmid DNA. 

4.7/5.0
|3 Reviews


SE300 miniVE Modular Vertical Unit

Hoefer Inc. Europe

Perform both electrophoresis and electro transfer in one sturdy, compact unit. The Hoefer® SE300 miniVE vertical electrophoresis system performs vertical gel electrophoresis on mini-format gels. The basic unit includes two electrophoresis modules. Each module holds one gel sandwich, 10 cm wide and up to 10.5 cm long. One gel can be cast in place on each electrophoresis module.SE300 miniVE Modular Vertical Unit Features: Q…

5.0/5.0
|1 Review


Autogizer

Tomtec Inc.

Two Autogizer Models• Model 700 includes five Model 200 homogenizers(1/5 hp 5,000 to 30,000 rpm) • Model 701 includes four Model 250 homogenizers(3/4 hp 10,000 to 30,000 rpm)Also available with 1 to 5 sonic probes. Flexibility• Can run individual tubes or full racks Fully Programmable Row by Rowwith multiple operator set programs• Up and Down Cycling with height settings• Rate of Cycling• Timing of Cycling Advanced Cutter…

4.7/5.0
|2 Reviews

Costar® 24-well Clear Flat Bottom Ultra-Low Attachment Multiple Well Plates, Individually Wrapped, Sterile

Corning Life Sciences

Ultra-Low Attachment Plates feature a covalently bound hydrogel layer that effectively inhibits cellular attachment Surface minimizes protein absorption, enzyme activation, and cellular activation Surface is non-cytotoxic, biologically inert, and nondegradable Nonreversible lids with condensation rings to reduce contamination Individual alphanumerical codes for well identification Uniform footprint for ease in stacking…

5.0/5.0
|3 Reviews

VG Prima dB - Process Mass Spectrometer

Thermo Fisher Scientific

VG PRima dB- Process Mass Spectrometer The comination of superior analytical performance, backed by VG application knowledge and powerful Gasworks and Prima Wizard software packages, established the VG Prima as the world's top selling process mass spectrometer system. The new VG Prima dB now sets new standards for process mass spectrometer performance and reliability. Product Detail The VG Prima dB is the latest in the VG…

4.7/5.0
|2 Reviews

Corning® Half Area 96-well Clear Flat Bottom UV-Transparent Microplate, 25 per Bag, without Lid, Nonsterile

Corning Life Sciences

Half Area 96 well UV microplate has a UV-transparent well bottom and is ideal for determining protein and/or nucleic acid concentrations Certified for low background and consistent performance at 260 and 280nm Certified DNase- and RNase-free UV-transparent bottom is molded directly to an acrylic base for greater strength and maximum leak resistance Half Area microplate has well volume of 205 µL; working volumes of 25 to…

4.7/5.0
|3 Reviews

miVac SpeedTrap

Genevac

Unique frost free cold trap - the miVac SpeedTrap does not need  defrosting, all solvents (including water) collect as liquids and can be eaily emptied - collection jar is simply removed by quarter turn. The miVac SpeedTrap is compact, requiring little bench space and suitable for use with a wide range of solvents, from volatile organic solvents through to water and some of the higher boiling point solvents. The SpeedTrap i…

5.0/5.0
|1 Review

Cellhost - A Fully Automated System for Cell Cultures

Hamilton Company

Cellhost, a fully automated cell culture system, was co-developed by Hamilton and Life & Brain (Bonn, Germany). The novel fully automated 3D scale-up system (3D CellHOST™) employs magnetic microcarriers (GEM™), an integrated incubator (BioLevitator™) and a liquid handling Workstation (STARlet™) for automated sampling and media changes. The technology is based on levitation of microcarriers in rotating tubes (LeviTubes™) and p…

5.0/5.0
|1 Review

Corning® Cell Lifter

Corning Life Sciences

Ideal tool for harvesting stem cells and colonies while maintaining high viability One piece design for better control Blade design minimizes cell damage and ensures even contact with the growth surface Individually wrapped Sterilized by gamma radiation and nonpyrogenic

4.7/5.0
|2 Reviews


DIG-High Prime DNA Labeling and Detection Starter Kit I

DIG-High Prime labeled probes can be used in Southern-, northern- and dot-blot analysis, as well as colony and plaque hybridizations. This kit offers random-primed labeling of DNA templates with DIG-11-dUTP, alkali-labile, and color detection of the DIG-labeled hybrids. This kit was assembled with convenience in mind, offering a ready-made blocking solution, combined stock solution of NBT/ BCIP, and DIG Easy Hyb granules. The…

4.7/5.0
|1 Review

Rotary Evaporators

Heidolph Instruments GmbH

Unique modular concept consists of rotary evaporator, vacuum pumps, controllers and chiller All components are designed to function harmoniously High efficiency with limited space requirements   Self contained design eliminates the need for water, dry ice and vacuum sources All evaporators can be upgraded for future needs Complete system available from one manufacturer High distillation rates guarantee the fastest…

4.9/5.0
|14 Reviews

MagNA Pure LC Instrument

Robotic workstation for fully automated nucleic acid preparation and filling of LightCycler® Capillaries, 96-well PCR plates, and tubes suitable for the most commonly used PCR instruments Benefits Save time with rapid, fully automated isolation of high-quality DNA, RNA, and mRNA. Obtain reliable, reproducible results. Benefit from high flexibility in sample type and volume, as well as elution volume and post-elution p…

5.0/5.0
|1 Review

Thermo Scientific 384-Well Full-Skirted Plates

Thermo Fisher Scientific

Designed for high-throughput PCR, the Thermo Scientific 384-well plate is compatible with the majority of 384 block PCR and sequencing instruments. it has a maximum well volume of 40 µL and a working volume of 25 µL. This 384-well plate is compatible with all major 384 block thermal cyclers, and it hsa a cut corner at the A24 location. Highlights • Fully skirted for use with automated systems • Compatible with all leading 384…

4.5/5.0
|11 Reviews

TaqMan Gene Expression Assays

Thermo Fisher Scientific

TaqMan® Gene Expression Assays are a comprehensive collection of over 1,000,000 probe and primer sets for quantitative gene expression analysis of 13 species including human, mouse, rat, Arabidopsis, Drosophila, and C. elegans genes. These assays let you quickly, easily, and affordably perform precise gene expression studies using real-time PCR. TaqMan®-based assays provide unmatched sensitivity, specificity, and reproducibi…

4.7/5.0
|14 Reviews

ABgene 2.2ml Deep Well Plate

Thermo Fisher Scientific

ABgene 2.2ml Storage Plates are manufactured and in a class 100,000 clean room environment to ensure that each plate is contamination free. Plates are made using virgin medical grade polypropylene and have highly polished surfaces making them low binding and chemically resistant. Rigid side walls and industry standard footprint make plates suitable for automation and robotic handling, as well as for low throughput applications…

4.7/5.0
|1 Review


EXP® Pre-Column Filters

Optimize Technologies, Inc.

The EXP® Pre-Column Filter is ideal for protecting small-particle UHPLC columns at extreme pressures. Such techniques analyze samples in the most demanding applications, which can decrease the life of these expensive columns. EXP® Pre-Column Filters help extend that life and protect your column investment without sacrificing performance. Free-Turn® architecture allows the user to change cartridges by hand without breaking flui…

4.7/5.0
|4 Reviews

OPTI-PAK® Trap Columns

Optimize Technologies, Inc.

The OPTI-PAK Trap Columns unique hardware design integrates a PEEK holder with an auto-adjusting stem which provides a fluid interface with any 10-32 standard injector port, and guarantees a zero-dead-volume connection despite variances in tube stop depth. A proprietary method of frit placement allows the packed stem to be positioned directly into the flow path, which eliminates all excess swept volume. Less swept volume trans…

5.0/5.0
|1 Review


TubeSpin Bioreactor

TPP Techno Plastic Products AG

TPP TubeSpin® Bioreactors have proven their advantages in large scale screening and optimization processes of suspension cells. The optimization of the parameters, important for the production up-scaling, can be evaluated with small amounts maximizing the number of parallel experiments at the same time. Features of the TubeSpin® Bioreactor 50 • Working volume 1-35ml • Conical form • 5 openings (A,B,C,D,E) of different size abo…

5.0/5.0
|1 Review

Echo® 525 Liquid Handler

Beckman Coulter Life Sciences

The Echo 525 platform, like the other Echo liquid handler models, is designed to use sound energy to transfer reagents. Unlike the other Echo models, the Echo 525 platform transfers at a larger volume increment (25 nL). This enables the more rapid transfer of aqueous reagents required in biochemical and genomics assays setup.

4.8/5.0
|4 Reviews

Microlab 600 Series Diluter

Hamilton Company

The Microlab 600 is a highly precise syringe pump with a graphical user interface designed to quickly and easily dilute and dispense liquids. Every laboratory has tasks that are too small to automate and too large to reliably accomplish by hand. The Microlab 600 is a semi-automated liquid handler designed specifically for these in-between applications. The Microlab 600 increases throughput and consistency while reducing cost a…

4.5/5.0
|2 Reviews