Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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LowCell ChIP Kit Protein A

Diagenode

The Diagenode’s LowCell# ChIP kit is the only complete magnetic bead based ChIP (Chromatin Immunoprecipitation) kit that can be used with as low as 1000 - 10 000 cells per IP. Ideal for Stem cells, embryos and biopsies. Use from 1,000 - 100,000 cells per IP Improved handling and reproducibility by the use of magnetic beads and special Magnetic rack (0.2 ml tubes) Optimized purification and de-crosslinking step One…

5.0/5.0
|1 Review





HisPur™ Ni-NTA Superflow Agarose

Thermo Fisher Scientific

Thermo Scientific HisPur Ni-NTA Superflow Agarose is a nitrilotriacetic acid (NTA) modified Superflow 6 support charged with divalent nickel (Ni+2) designed for FPLC purification of poly-histidine-tagged proteins. Features of HisPur Ni-NTA Superflow Agarose: • High capacity—binds greater than 20 mg of His-tagged GFP per mL of resin at a linear flow rate of 300 cm/hour • High purity—provides greater than 80% purity of el…

4.7/5.0
|1 Review




G:BOX mini

Syngene

G:BOX mini is a compact, multi application imaging system for accurately imaging mini and midi fluorescence and visible gels, multiplex fluorescence westerns, stain-free gels and chemiluminescent blots.

5.0/5.0
|1 Review

Duolink In Situ Red Starter Kit Mouse/Rabbit

Merck

Application Duolink® proximity ligation assay(PLA®) allows for endogenous detection of protein interactions, post translational modifications, and protein expression levels at the single molecule level in fixed cells and tissue samples. Follow the Duolink® In Situ Fluorescence Protocol to use this product. A set of short instructionsis also available. Visit our Duolink® PLA Resource Center for information on how to ru…

4.7/5.0
|3 Reviews

Invitrogen™ LIVE/DEAD™ Fixable Near-IR Dead Cell Stain Kit

Thermo Fisher Scientific

The LIVE/DEAD Fixable Near-IR Dead Cell Stain Kit provides the stable components to determine the viability of cells prior to the fixation and permeabilization required for intracellular antibody staining or prior to elimination of biohazardous materials using formaldehyde fixation. The amine-reactive LIVE/DEAD Fixable Near-IR Dead Stain is an amine reactive dye that binds covalently to intracellular and extracellular amines i…

5.0/5.0
|1 Review

Thermo Scientific™ Pierce™ Rapid Gold BCA Protein Assay Kit

Thermo Fisher Scientific

The Pierce Rapid Gold BCA Protein Assay Kit is a two-component protein assay to measure total protein concentration that offers high-precision, detergent-compatibility assay. Using the same copper-chelating technology as the well-known Pierce BCA Protein Assay, the Pierce Rapid Gold BCA Protein Assay provides comparable accuracy but with a 5 minute, room temperature incubation, eliminating the need to wait or expose the sample…

5.0/5.0
|1 Review


Click-IT™ AHA (L-Azidohomoalanine)

Thermo Fisher Scientific

Click-iT® AHA (L-azidohomoalaine) provides a fast, sensitive, non-toxic and most importantly non-radioactive alternative to the traditional radioactive technique, 35S-methionine for the detection of nascent protein. AHA is an amino acid analog that contains a very small modification, specifically an azido moiety that can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes…

5.0/5.0
|1 Review

NanoBRET™ TE Intracellular Kinase Assays

Promega Corp.

Measure Kinase-Ligand Affinity in Live Cells The NanoBRET™ Target Engagement (TE) Intracellular Kinase Assay measures compound binding at select target kinases in intact cells. The assay is based on the NanoBRET™ System, an energy transfer technique designed to measure molecular proximity in living cells. The NanoBRET™ TE Assay measures the apparent affinity of test compounds by competitive displacement of the NanoBRET™ tra…

4.7/5.0
|22 Reviews
  • Best New Drug Discovery & Development Product of the Year

BD Accuri™ C6 Plus Flow Cytometer

BD Biosciences

The BD Accuri™ C6 Plus personal flow cytometer is the newest generation of the BD Accuri™ platform. Enhanced sensitivity, reliability, and capabilities bring flow cytometry even more within reach for new and experienced flow cytometry researchers. With its compact 11 x 14.75 x 16.5-inch footprint, light weight of 30 lb, and operational simplicity, the BD Accuri C6 Plus supports a wide array of applications including immunol…

4.6/5.0
|14 Reviews


Wes

Wes™ lets you separate and analyze proteins by size from 2-440 kDa

4.8/5.0
|5 Reviews

FluorChem R

Satisfy everyone in your lab with an imager that does it all—and takes the complication out of getting reliable, fully analyzed data too! 

5.0/5.0
|2 Reviews

FluorChem M

The FluorChem™ M system offers true application flexibility with the smoothest software you'll ever use.

4.7/5.0
|1 Review

FluorChem Q

FluorChem™ Q system is a slam-dunk solution for quantitative Western blot imaging and analysis.

4.7/5.0
|1 Review