Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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SpectraMax 190 Absorbance Microplate Reader

Molecular Devices®

The SpectraMax® 190 UV-Vis Microplate Spectrophotometer from Molecular Devices is ideal for life science applications, especially DNA analysis. The multi-channel design truly mimics a dual-beam spectrophotometer. Each sample has a discrete sample beam and reference beam so that each well is measured directly, eliminating error due to variations in light output between the optic fibers. The system consists of eight sample beams…

4.2/5.0
|2 Reviews
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BD LSR II System

BD Biosciences

Four-laser, 18-color benchtop flow cytometer Building on the ease of use and flexibility of the BDTM LSR, the first UV benchtop analyzer, BD Biosciences introduces the BDTM LSR II. The BD LSR II has performance, capabilities, and flexibility never seen before in a benchtop analyzer. Free up your high-performance cell sorter by moving your application(s) that require a UV laser to the BD LSR II. The BD LSR II can be config…

4.0/5.0
|16 Reviews
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BD FACSAria™ III

BD Biosciences

The BD FACSAria™ III sorter is built on the solid foundation of patented technologies, superior multicolor performance, and legendary ease-of-use that opened the complex world of cell sorting to a broader audience of researchers and wider range of applications. The fluidics and optical systems are precisely integrated to maximize signal detection. A patented flow cell with gel-coupled cuvette and patented octagon and trigon de…

3.9/5.0
|7 Reviews
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BD FACSDuet™ sample preparation system

BD Biosciences

The BD FACSDuet™ sample preparation system provides a powerful new level of performance to move the pace of your lab forward. With pre-analytical automation and process standardisation, the BD FACSDuet™ drives consistency and workflow efficiency. Allowing for automated cocktail preparation and supporting the use of non-BD reagent vials, the BD FACSDuet™ greatly enhances flexibility and standardisation.  Designed to complement…

3.7/5.0
|1 Review
  • Best New Clinical Laboratory Instrumentation of the Year
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BD FACSAria Fusion

BD Biosciences

The BD FACSAria™ Fusion improves on the solid foundation of patented technologies, exceptional multicolor performance, and ease-of-use that was first brought to the world of sorting by the launch of the BD FACSAria™ sorter in 2003. Now this sorting know-how is combined with best-in-class biosafety expertise to create the BD FACSAria Fusion, a fully integrated advanced cell sorter and biosafety solution for research laboratorie…

4.5/5.0
|10 Reviews
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BD FACSCanto II

BD Biosciences

Cell analyzer with proven reliability The BD FACSCanto™ family of benchtop analyzers features reliable performance and accurate results for experiments requiring up to 10 parameters. Numerous innovations make the system easy to use, powerful, and productive. A fixed alignment flow cell, for example, minimizes startup time and improves reproducibility. And a patented optical design maximizes signal detection and increases…

3.8/5.0
|8 Reviews
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CellTox™ Green Cytotoxicity Assay

Promega Corp.

The CellTox™ Green Cytotoxicity Assay measures changes in membrane integrity that occur as a result of cell death. The assay is intended to assess cytotoxicity in cell culture after experimental manipulation. The assay system uses a proprietry asymmetric cyanine dye that is excluded from viable cells but preferentially stains the DNA from dead cells. When the dye binds DNA released from cells, its fluorescence properties are s…

4.3/5.0
|1 Review
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QuantiFluor® dsDNA System

Promega Corp.

The QuantiFluor® dsDNA System contains a fluorescent DNA-binding dye that enables sensitive quantitation of small amounts of double-stranded DNA (dsDNA) in solution.   The quantitation of dsDNA is a very important step in many biological applications, particularly in standard molecular biology techniques. The dye shows minimal binding to single stranded DNA (ssDNA) and RNA, allowing specific quantitation of dsDNA. The…

4.3/5.0
|2 Reviews
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Recombinant RNasin® Ribonuclease Inhibitor

Promega Corp.

Recombinant RNasin® Ribonuclease Inhibitor reliably protects your RNA samples from RNase degradation.   RNases are ubiquitous and degradation can cause significant damage to RNA, hindering downstream reactions. Protect your sample with the most robust inhibitor available-- Recombinant RNasin® Ribonuclease Inhibitor. Recombinant RNasin Ribonuclease Inhibitor Features & Benefits:   Inhibits a broad spectrum o…

4.2/5.0
|3 Reviews
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CellTiter-Glo® 3D Cell Viability Assay

Promega Corp.

The CellTiter-Glo® 3D Cell Viability Assay is a homogeneous method to determine the number of viable cells in 3D cell culture based on quantitation of the ATP present, which is a marker for the presence of metabolically active cells.   This ready-to-use reagent is based on the original CellTiter-Glo® Luminescent Cell Viability Assay chemistry and eliminates the need to combine buffer with lyophilized substrate when prepa…

4.3/5.0
|5 Reviews
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FuGENE ® HD Transfection Reagent

Promega Corp.

FuGENE® HD Transfection Reagent is a novel, nonliposomal formulation designed to transfect DNA into a wide variety of cell lines with high efficiency and low toxicity. The protocol does not require removal of serum or culture medium and does not require washing or changing of medium after introducing the reagent/DNA complex. Additionally, the FuGENE® HD Transfection Reagent has been shown to support transfection in che…

4.3/5.0
|6 Reviews
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NanoBRET™ Target Engagement BET BRD Assays

Promega Corp.

The NanoBRET™ Target Engagement (TE) Intracellular BET BRD Assay measures compound binding at select BET bromodomain target proteins within intact cells. This target engagement assay is based on the NanoBRET™ System, an energy transfer technique designed to measure molecular proximity in living cells

4.3/5.0
|1 Review
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Dual-Luciferase ® Reporter Assay System

Promega Corp.

The Dual-Luciferase® Reporter (DLR™) Assay System(a–f) provides an efficient means of performing two reporter assays. In the DLR™ Assay, the activities of firefly (Photinus pyralis) and Renilla (Renilla reniformis or sea pansy) luciferases are measured sequentially from a single sample. The firefly luciferase reporter is measured first by adding Luciferase Assay Reagent II (LAR II) to generate a luminescent signal lasting at l…

4.4/5.0
|9 Reviews
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Steady-Glo ® Luciferase Assay System

Promega Corp.

High-throughput quantitation of firefly (Photinus pyralis) luciferase expression in mammalian cells is commonly performed by batch processing of 96- and 384-well plates. Steady-Glo® Luciferase Assay System(a,b,c) is designed for this purpose by providing long-lived luminescence when added to cultured cells. The homogeneous assay provides signal half-lives of over 5 hours in commonly used cell culture media without prior sample…

4.5/5.0
|5 Reviews
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