Drug discovery > Target Discovery Products & Reviews

Crystal Clear Imaging. Unparalleled Speed. ROCK IMAGER ® - Crystallization Imagers are a series of automated imaging systems designed for protein crystallization screening. Capture superior quality images of your protein drops while learning critical information about your crystals. ROCK IMAGERs are available with various plate capacities and imaging features, so there is a model to fit every lab's budget and workflow.

Through its exceptional image quality and the widest size range available, FlowCam® 8000 represents state-of-the-art particle imaging technology. Analyze thousands of particles in less than a minute and comprehensively characterize the size, count, morphology, and identity of subvisible and visible particulates in their native solvent.

The Genizer HandExtruder is a cost-effective tool for micro liposome extrusion. Users manually push the syringe plunger to force the sample through a filter membrane, repeating the process 5 to 10 times for consistent liposome sizes.

BellBrook Labs Transcreener ® UDP² Glycosyltransferase Assays

The Vi-CELL Series Cell Viability Analyzers provide an automatic and cost effective means to perform the trypan blue dye exclusion method.

The Biochrom 30+ Amino Acid Analyzer is trusted by hospitals, reference labs, pharmaceutical and industrial labs worldwide. It accurately detects and quantifies amino acids and their derivatives in complex samples. Applications include: detection and monitoring of in-born errors of metabolism, PKU testing, clinical analysis, proteomics, drug synthesis, infusion fluids, and quality control. The system is based on cation exc…

The Finnigan TSQ Quantum Series of mass spectrometers are the most advanced and powerful triple quadrupole mass spectrometers available. The Quantum Series mass spectrometers feature the patented HyperQuad™ mass analyzer technology, a rugged orthogonal source, and a completely redesigned analyzer geometry for maximum sensitivity, precision, and reliability. The Quantum Series triple quads are the only commercial triple quads a…

This advanced, high performance ion trap - Fourier Transform mass spectrometer is the right tool for your toughtest analytical challenges in metabolic studies, proteome analysis, pharmaceutical discovery, and all other applications. Product detail: The Finnigan LTQ FT™ combines the most advanced Ion Trap and Fourier Transform Ion Cyclotron Resonance technologies into a single instrument with unprecedented analytical power…

Small-Scale Automation with Large-Scale Results   Access™ laboratory workstations multiply the benefits of the Echo® liquid handler by improving overall assay throughput and reproducibility. With the ability to integrate a variety of devices and the modularity to scale when needed, each workstation offers the flexibility required by frequently-changing assay requirements.  All Access workstations are optimized at install and i…

Are you looking for a new pipetting partner for daily reliable assistance in your lab? Xiril’s Neon 100-1-8 is ready to take over several liquid handling jobs, such as PCR-setup, reformatting, dilution series, archiving, hit picking, extractions etc. – while you are free for other tasks! The technology of the robotic workstation Neon 100-1-8 crosses boundaries with its pipetting arm, holding eight channels that work independen…

Recombinant protein A covalently bound to magnetic beads. These beads provide users a rapid, reproducible and efficient reagent for collecting immunocomplexes for chromatin immunoprecipitations (ChIP) assays. Compared with conventional protein A agarose beads, protein A magnetic beads significantly reduce the handling time and mechanical stress on target immunocomplexes.

This kit provides the reagents required for the detection of citrulline-containing proteins by Western blot analysis with the anti-Citrulline antibody. Detection is a two-step process in which citrulline-containing proteins immobilized on nitrocellulose or PVDF are formaldehyde-cross linked to the membrane to improve protein retention, followed by modification of citrulline residues with 2,3-butanedione monoxime and antipyrine…

The ChIPAb+ EZH2, clone AC22 antibody/primer set includes the EZH2, clone AC22 antibody, a negative control antibody (purified mouse IgG), and qPCR primers which amplify a 135 bp region within the promoter of the human MYT-1 gene. The EZH2, clone AC22 antibody and negative control antibodies are supplied in a scalable "per ChIP" reaction size and can be used to functionally validate the precipitation of EZH2-associated chromat…

Protein G covalently coupled by cyanogen bromide to highly cross-linked 4% agarose beads. Stable in all aqueous buffers used in Protein G chromatography.

Beta-Galactosidase Tissue Stain Base Solution. It is one of the components required to visualize the expression of the LacZ reporter gene in fixed tissue.

The UPSTATE colorimetric STAR (Signal Transduction Assay Reaction) ELISA kit is a solid phase sandwich enzyme linked immunosorbent assay that provides a fast, sensitive method to detect specific levels of signaling targets in whole cell extracts. The AKT1 plate is coated with a specific mouse monoclonal anti-AKT1 capture antibody on the microwells of the 96-well clear plate. Many of the reagents are supplied in ready-to use fo…

Five different pore sizes from 0.1 to 5.0 µmPre-sterilized units also availableFast filtration and highly reproducible performanceUse in fixed-angle rotors for 1.5 mL tubes

• High recovery Ultracel regenerated cellulose membrane in a range of molecular weight cut-offs• High retentate recovery of >90%• Vertical membrane reduces concentration polarization for ultra-fast spin times (as fast as 10–15 minutes)• Heat-sealed membrane minimizes downstream extractables• 100% integrity tested for reliable performance• Convenient sample monitoring with translucent housing and volume gradations• Direct pipet…

• High recovery Ultracel regenerated cellulose membrane in a range of molecular weight cut-offs• High retentate recovery of >90%• Vertical membrane reduces concentration polarization for ultra-fast spin times (as fast as 5 minutes)• Heat-sealed membrane minimizes downstream extractables• 100% integrity tested for reliable performance• Convenient sample monitoring with translucent housing and volume gradations• Direct pipette s…

The MILLIPLEX® MAP Rat Thyroid Hormone TSH Panel - Single Plex is used for the simultaneous quantification of the following Rat analytes: TSH

The MILLIPLEX® MAP Rat Stress Hormone Panel is used for the simultaneous quantification of the following Rat analytes: ACTH, Corticosterone, Melatonin

The compact, benchtop ViBE BioAnalyzer is the ideal research tool for assay development or small to medium size studies which require highly-sensitive detection and quantitation of proteins in complex biological mixtures with real-time results. The small foot-print BioAnalyzer can be easily scaled-up to a ViBE Workstation for higher throughput and walk-away operation. The ViBE BioAnalyzer   •  Ideal for research applications a…

The FlowSight flow cytometer offers high performance in a small package. Its innovative design increases signal and minimizes noise to provide unmatched fluorescence sensitivity. Twelve standard detection channels simultaneously produce brightfield, darkfield and up to ten channels of fluorescence imagery of every cell. With these unique capabilities, the FlowSight enables a broad range of applications. Intuitive: Easy-to-use,…

The FDSS7000, the top-rated model , includes new features including 1536 dispensing tips and multiple wash tanks. The FDSS7000 continues to offer real-time kinetic analysis of various types of both nonadherent and adherent cells. The FDSS7000 offers field upgradable components including the 'FRET attachment', robotics integration, additional heads, and more allow for a customized system for you now and in the future. Features…

The basic Nucleofector® II Device is a single cuvette based system that has been used in research labs since 2001. It allows efficient transfection of hard-to-transfect cell lines and primary cells with different substrates, e.g. DNA vectors or siRNA oligonucleotides, in low throughput format. What benefits are important for your work? Efficient transfection in single cuvette format? Up to 90% efficiency with plasmid DNA…