UHPLC and HPLC Products & Reviews

The ACQUITY UPLC® Evaporative Light Scattering (ELS) Detector is designed specifically for optimal UPLC®/ELS performance in a small footprint. When your analytes have poor to no UV/Vis response, or don’t ionize well by mass spectrometry, the ACQUITY UPLC ELS Detector with the ACQUITY UPLC System lets you analyze more molecules (including sugars, triglycerides, phospholipids, antibiotics, and natural products) in a single analy…

The ACQUITY UPLC H-Class PLUS Bio System delivers the benefits of UPLC's resolution, sensitivity, and throughput in a system purpose-built for the analysis of proteins, peptides, nucleic acids, and glycans.

The 2545 Quaternary Gradient Module is a four solvent, low pressure mixing gradient pump (up to 150 mL/min) that serves as a solvent delivery device for purification systems. Features: • Four solvent gradient selection • Control from MassLynx, Empower, or console allowing scale up via a familiar software interface • Interfaces to a variety of detectors and peak fraction collectors for optimum purifications • Allows UV or MS di…

UPLC Technology Extends To Two Dimensions For chromatographers who require additional capabilities to increase their speed of analysis, gain sensitivity and selectivity, and perform orthogonal separations, ACQUITY UPLC® Systems can meet these needs by controlling multiple valves and pumps for 2D separations. The resolution, sensitivity, and throughput benefits of UPLC® Technology are even more important in 2D applications. Wat…

HisTrap FF is a ready-to-use column, prepacked with precharged Ni Sepharose 6 Fast Flow for preparative purification of histidine-tagged recombinant proteins by immobilized metal ion affinity chromatography (IMAC).

Designed to meet the demands of modern, large-scale manufacturers Capto Q’s shorter processing times can reduce exposure of the target protein.

High purity, Type B, spherical silica support. 100A pore size. 1.8um, 3um, & 5um partical sizes. Variety of stationary phases.

With mid-size capacity and throughput, the VERITY 271 HPLC systems provide hundreds of configurations for semi-preparative and preparative purifications.

Polysaccharide Chiral HPLC and SFC Columns at a Very Affordable Price. Optimize your chiral separation and chiral purification with Lux® polysaccharide chiral HPLC columns. The Lux family of amylose and cellulose chiral selectors provides a variety of complementary selectivities that allow you to screen for the most effective chiral separation under Reversed Phase, Polar Organic, Normal Phase, and SFC conditions. With numer…

Highly reproducible pentafluorophenyl phase exception for halogenated, conjugated, isomeric, or highly polar compounds.

Combined C18 and polar modified surface that provide polar and non-polar retention alongside 100% aqueous stability.

The new Kinetex 2.6 µm PS C18 phase is beneficial for all types of compounds (acids, bases, neutrals), but especially for the analysis of polar basic compounds. The phase has demonstrated increased polar analyte retention, improved peak shape for troublesome basic analytes under typical reversed phase conditions, and a unique multi-modal interaction selectivity making it indispensable tool for multi-compound and metabolite pro…

Develosil HPLC columns provide high efficiency, high resolution separations.

RP-HPLC for Protein/Peptide Analysis and PurificationJupiter® HPLC columns offer optimized reversed phase solutions for protein and peptide characterization and purification. A wide variety of phases (C18, C12, C5, C4) and dimensions (capillary-preparative)/bulk media are available to support the majority of separation requirements.Jupiter 300 - 300 Å columns designed to purify intact proteinsJuptier Proteo - 90 Å columns eng…

Setting the Standard for pH Method DevelopmentRugged reversed phase HPLC columns that offer extended lifetime under extreme pH conditions and excellent stability for reproducible, high efficiency separations. Take full advantage of high and low pH conditions (pH 1-12) to manipulate selectivity Expect longer column lifetime with patented TWIN-NX™ technology Ideal for analytical and preparative separations of basic and acid…

Economical, high efficiency columns to purify and/or characterize proteins, peptides, and other biomolecules including antibodies, aggregates, and PEGylated proteinsHigh performance: Analytical and preparative BioSep columns offer high resolution, maximum efficiency, and exceptional peak asymmetryImproved recovery: Extremely inert media offers advantages for accurte quantitationFlexible method development: 3 phases options (20…

The Biochrom 30+ Amino Acid Analyzer is trusted by hospitals, reference labs, pharmaceutical and industrial labs worldwide. It accurately detects and quantifies amino acids and their derivatives in complex samples. Applications include: detection and monitoring of in-born errors of metabolism, PKU testing, clinical analysis, proteomics, drug synthesis, infusion fluids, and quality control. The system is based on cation exc…

CHIRAL TECHNOLOGIES offers an expanded line of immobilized polysaccharide chiral stationary phases (CSPs), CHIRALPAK IA™, IB™, and IC™. These immobilized CSPs allow the use of a highly extended range of solvents and offer new separation selectivities relative to conventionally coated CSPs. All three are based on high-efficiency 5-µm diameter spherical silica (or 20-µm for scale-up to semi-preparative and preparative applicatio…

OpenLab CDS EZChrom provides superior control of Agilent LC and GC instruments, plus the most complete control of other vendors’ instruments.

Polar-modified column; available in 3.0, 4.0, 4.6, 10, 21.2 and 50 mm id;  30 - 250 mm length. From the collapse-resistant pore structure of the base silica, to the "wettability" engineered into the bonded phases, Polaris columns have been designed for high aqueous conditions.  The combination of high-phase density bonding, ultra pure silica and silanol shielding leads to excellent peak shape among polar-modified columns.

ZORBAX 80Å StableBond columns are made using bulky, patented, unique silanes that sterically protect the siloxane bond. Acid labile endcapping reagents are not used. The result is vastly improved column life and extraordinary chemical and temperature stability in the pH 1–6 range for a wide variety of phases (SB-Aq, SB-C3, SB-CN, SB-Phenyl, SB-C8, and SB-C18). Excellent peak shape is expected for many basic compounds because…

Bonus-RP columns provide unique selectivity and applicability for mid pHs with an embedded amide linkage in the C14-alkyl chain. At pH 7 Bonus-RP provides excellent peak shape for even the most challenging basic compounds.

The 1290 Infinity II Refractive Index Detector (RID) is a UHPLC RID detector that provides excellent sensitivity, resolution, and sample throughput for UHPLC DRI experiments. The 1290 Infinity II RID is a equipped with an ultralow dispersion microflow cell and a data rate of 148 Hz, which significantly reduces run times for higher sample throughput and improved resolution and sensitivity.  

The 1260 Infinity II Bio-Inert LC is a dedicated solution for analysis of large biomolecules in biological samples, including monoclonal antibody (mAb) and protein analysis. Metal-free components in the sample flow path and the absence of iron and steel in solvent delivery lines ensure the integrity of your biomolecules, minimize unwanted surface interactions, and increase column lifetime.

The 1260 Infinity II Degasser is suitable for analytical applications with flow rates up to 10 mL/min and up to four solvents. It is highly recommended for GPC/SEC applications using refractive index detection. It reduces baseline noise and quenching effects due to high degassing capacity.