Enzyme Inhibitors Products & Reviews

The Protein Transport Inhibitor Cocktail (500X), a cocktail of Brefeldin A and Monensin, is used for assays in which prevention of protein transport to the extracellular space is desired and has been specifically formulated for use as a negative control for the Cell Stimulation Cocktail (plus protein transport inhibitors) (500X) (cat. 00-4975). Addition of this cocktail to cells in culture inhibits the intracellular protein se…

lyophilized powder, 3-8 TIU/mg solid

powder, BioReagent, suitable for cell culture, ≥98% (HPLC)  

≥99% (agarose gel electrophoresis)

?2.0 units/mg protein (modified Warburg-Christian)

≥90% (HPLC)

Diphtheria toxin may be used as a toxin element in the construction of immunotoxin for cell specific cytotoxicity. The translocation domain of bacterial toxins with natural endosome escape mechanism has been used in the development of efficient nonviral vectors for applications in gene therapy.

solid, synthetic  

microbial  

protease inhibitor  

≥90% (HPLC)  

≥98% (HPLC), powder  

thymidylate synthase inhibitor

MEK/ERK pathway inhibitor; Inhibits MEK1 and MEK2

Activin/Nodal/TGFß pathway inhibitor; Inhibits ALK5

Activin/BMP/TGF-ß pathway inhibitor; Inhibits ALK5

Antioxidant; COX-1 inhibitor

Epigenetic modifier; Inhibits DNA methyltransferase (DNMT)

RHO/ROCK pathway inhibitor; Inhibits ROCK2

cAMP pathway activator; Inhibits type 4 cyclic nucleotide phosphodiesterases (PDE4)

Epigenetic modifier; Inhibits HDAC1 and HDAC3

p38 MAPK inhibitor

p38 MAPK inhibitor

WNT pathway activator; Inhibits GSK3a and GSK3ß

Activin/BMP/TGF-ß pathway inhibitor; Inhibits ALK4, ALK5, and ALK7