ADME-Toxicology Products & Reviews

The CellTox™ Green Cytotoxicity Assay measures changes in membrane integrity that occur as a result of cell death. The assay is intended to assess cytotoxicity in cell culture after experimental manipulation. The assay system uses a proprietry asymmetric cyanine dye that is excluded from viable cells but preferentially stains the DNA from dead cells. When the dye binds DNA released from cells, its fluorescence properties are s…

The CellTiter-Glo® 3D Cell Viability Assay is a homogeneous method to determine the number of viable cells in 3D cell culture based on quantitation of the ATP present, which is a marker for the presence of metabolically active cells.   This ready-to-use reagent is based on the original CellTiter-Glo® Luminescent Cell Viability Assay chemistry and eliminates the need to combine buffer with lyophilized substrate when prepa…

The RealTime-Glo™ MT Cell Viabiilty Assay measures viability of cells in a non-lytic, real-time live-cell format, saving time, cells and reagent costs.

The CellTiter-Blue® Cell Viability Assay provides a homogeneous, fluorescent method for monitoring cell viability. The assay is based on the ability of living cells to convert a redox dye (resazurin) into a fluorescent end product (resorufin). Nonviable cells rapidly lose metabolic capacity and thus do not generate a fluorescent signal. The homogeneous assay procedure involves adding the single reagent directly to cells cultur…

The Promega CytoTox 96® Non-Radioactive Cytotoxicity Assay is a colorimetric alternative to radioactive cytotoxicity assays. The CytoTox 96® Assay quantitatively measures lactate dehydrogenase (LDH), a stable cytosolic enzyme that is released upon cell lysis, in much the same way as [51Cr] is released in radioactive assays. Released LDH in culture supernatants is measured with a 30-minute coupled enzymatic assay that result…

Kainic Acid is a selective agonist of kainite receptors. It is also a potent excitant and neurotoxin. Chemical Name: (2S,3S,4S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid M.Wt: 213.23 Formula: C10H15NO4 Solubility: Soluble to 25nM in water Purity: >98% Storage: Store at room temperature

SYTOX™ Green Ready Flow™ Reagent is a bright, easy-to-use nucleic acid stain that helps to distinguish dead cells from live cells in flow cytometry assays. The dye can only enter cells that have lost membrane integrity and bind to DNA, acting as a counterstain when excited at 488 nm, with an emission peak of 523 nm. The reagent can be used with both mammalian and bacterial cells, and can be used in multiplex assays.FeaturesSta…

Detects apoptotic cells in situ by the indirect TUNEL method, utilizing an anti-digoxigenin antibody that's conjugated to a Fluorescein reporter molecule

Quickly and accurately identify tricyclics in serum samples with Thermo Scientific™ DRI™ Tricyclics Serum Toxicology Assays, excellent tools for emergency rooms when urine specimens are not conveniently available.

Suitable for protein quantification, suitable for cell analysis, and detection. Sufficient for ≤2,000 tests