Cell-Based Assays Products & Reviews

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Cell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.

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iLite® Cell-based Solutions

Svar Life Science AB

Svar specializes in creating cell-based Reporter Gene Assays with iLite® technology for a range of applications. This technology offers a precise, sensitive system with luciferase readout, suitable for testing drug activity, immunogenicity, and Fc-functional assays including CDC, ADCC, and ADCP activity. Svar's development capabilities cover nearly any pharmaceutical target, ensuring rapid and accurate assays.

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iLite® Cell-based Complement Bioassays

Svar Life Science AB

Svar specializes in creating cell-based Reporter Gene Assays with iLite® technology for a range of complement applications. This technology offers a precise, sensitive system with luciferase readout, suitable for assessing drug activity for different targets such as C5a, and through Complement-Dependent Cytotoxicity (CDC) activity.

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iLite® Custom Development & Cell-based Services

Svar Life Science AB

With their proprietary technology, the iLite® technology Svar can develop Report Gene Assays – that area cleverly designed, sensitive and specific cell based reporter-gene system with luciferase readout. Svar can develop assays for virtually any pharmaceutical target that allow an easy, rapid and accurate test format for a wide range of applications, such as Immunogenicity and Potency assays.

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iLite® Functional Bioassays

Svar Life Science AB

The iLite® Functional Bioassay portfolio consists of cell lines provided in an “assay-ready” format for a rapid and convenient workflow. The assay-ready format also reduces assay variability, optimizing its use in screening, characterization, stability, and potency studies. iLite cell lines can be tailored to virtually any biopharmaceutical target.

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iLite® Fc Effector Activity Bioassays

Svar Life Science AB

The iLite® Fc Effector Reporter Gene Bioassays Portfolio offers a variety of reporter gene cell lines and target cells that can be used in MOA-reflective assays to measure the Fc effect of antibodies and other biologics that specifically bind and activate Fc receptors. Using a Luciferase reporter gene system offers a convenient and powerful way of measuring antibodies' in vitro efficacy in triggering ADCC and ADCP.

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Gene Therapy Solutions

Svar Life Science AB

Svar offers assistance in gene therapy projects through robust platforms suited for all phases of drug development and experience from immunoassasy product development as well as their CRO services. Svar currently offer cell-based assays for Neutralizing antibody assessment and custom-made immunoassays for Total antibody assessment.

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Complement Biomarker Assays

Svar Life Science AB

Complement biomarker assays target selected biomarkers of high relevance. These assays are important and well-suited for analyses in drug development and academic research. They stand out with very low cross-reactivity and high specificity as they bind neo-epitopes of cleaved products or complexes, where this is relevant.

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Anti-CCP Assay

Svar Life Science AB

In diagnosis of Rheumatoid Arthritis (RA), the measurement of anti-CCP is integral. People who test positive for Anti-CCP, are very likely to develop or have already developed RA, but not all who have RA, necessarily develop anti-CCP. Early detection of RA is crucial for reducing tissue damage.

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Calprotectin Product Portfolio

Svar Life Science AB

Calpro, a Svar subsidiary, produced the first ever commercial kits available for measuring Calprotectin setting industry standards. It offers a broad range of assays, including ELISA, PETIA (Turbidimetric assay), and rapid Point-of-Care (PoC) and self-tests for IBD monitoring. Calpro also provides RUO ELISAs for various bodily fluids and a rapid CalproSmart test as an RUO product.

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CRO Services

Svar Life Science AB

Svar CRO Services provides direct value through an extensive toolbox of in-house products, scientific expertise, and end-to-end customizable solutions – everything to ensure the success of your drug development program.​

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Wieslab® Complement Classical Pathway (RUO & IVD*)

Svar Life Science AB

The Wieslab® Complement System Classical Pathway kit, available as IVD* and RUO, is a high-precision assay for detecting alternative complement pathway activity in human serum, the RUO is also suitable for primates and porcine samples. It uses ELISA technology with specific detection of C5b-9 for accurate results, offering advantages over traditional assays. *Subject to local registration.

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Wieslab® Complement MBL Pathway (RUO & IVD*)

Svar Life Science AB

The Wieslab® Complement System MBL Pathway kit, available as IVD* and RUO, is a high-precision assay for detecting alternative complement pathway activity in human serum, the RUO is also suitable for primates and porcine samples. It uses ELISA technology with specific detection of C5b-9 for accurate results, offering advantages over traditional assays. *Subject to local registration.

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Wieslab® Complement Screen (RUO & IVD*)

Svar Life Science AB

Wieslab® Complement Screen kit is available as both IVD* and RUO, detects Classical, MBL, and Alternative pathways in human serum samples using ELISA technology with specific detection of C5b-9 for accurate results offering advantages over traditional assays. The RUO is also suitable for primates and porcine samples. It is effective in complement therapeutics evaluation and drug development. *Subject to local registration.

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AAV NAb Assays

Svar Life Science AB

A two-component system of an AAV serotype-producing cell and a iLite®  responsive reporter cell that accurately provides a semi-quantitative NAb assay. The luciferase reporter gene expresses proportionally to the AAV transduction level, enabling precise detection of neutralizing antibodies against AAV. AAV-producing cells are available for serotypes 2, 5, 6, 8, and 9, with customizable options for other serotypes or derivative…

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Purified Antibodies

Merck

Purified antibodies are indispensable in spatial biology, providing unparalleled detail in cellular and molecular structure characterization. Our high-quality purified antibodies offer exceptional specificity, sensitivity, and reproducibility for diverse applications, from basic research to clinical diagnostics. Moreover, our purified carrier-free antibodies are ready to conjugate (RTC), streamlining your workflow.

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Aura

Halo Labs

Aura® is the particle and aggregate detection system that combines Backgrounded Membrane Imaging which images 100% of your sample to give you count, size, and morphological information, with up to 2 channels of Fluorescence Membrane Microscopy. Identify if particles are protein or not with the first FMM channel and determine if your sample contains lipids, hydrophobic entities, or other aggregates of your choice with a second…

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Aura PTx

Halo Labs

Aura® PTx gets you to your best formulation faster! Backgrounded Imaging (BMI) technology to give you accurate count, size, and morphology information about particles in your sample. Couple that with Fluorescence Membrane Microscopy (FMM), which gives you definitive ID of protein aggregates and an easy way to monitor polysorbate degradation.

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