Cell-Based Assays Products & Reviews

The Wieslab® Complement System Classical Pathway kit, available as IVD* and RUO, is a high-precision assay for detecting alternative complement pathway activity in human serum, the RUO is also suitable for primates and porcine samples. It uses ELISA technology with specific detection of C5b-9 for accurate results, offering advantages over traditional assays. *Subject to local registration.

The Wieslab® Complement System MBL Pathway kit, available as IVD* and RUO, is a high-precision assay for detecting alternative complement pathway activity in human serum, the RUO is also suitable for primates and porcine samples. It uses ELISA technology with specific detection of C5b-9 for accurate results, offering advantages over traditional assays. *Subject to local registration.

Wieslab® Complement Screen kit is available as both IVD* and RUO, detects Classical, MBL, and Alternative pathways in human serum samples using ELISA technology with specific detection of C5b-9 for accurate results offering advantages over traditional assays. The RUO is also suitable for primates and porcine samples. It is effective in complement therapeutics evaluation and drug development. *Subject to local registration.

The Factor P Functional assay is an ELISA that combines principles of the functional complement activity assays with the use of labeled antibodies specific for deposited complement proteins. The amount of deposited complement proteins is proportional to the functional activity of Properdin in the sample.

A two-component system of an AAV serotype-producing cell and a iLite®  responsive reporter cell that accurately provides a semi-quantitative NAb assay. The luciferase reporter gene expresses proportionally to the AAV transduction level, enabling precise detection of neutralizing antibodies against AAV. AAV-producing cells are available for serotypes 2, 5, 6, 8, and 9, with customizable options for other serotypes or derivative…

The iLite® CDC bioassay is based on a reporter gene and offers a convenient and powerful way of measuring antibodies' efficacy in eliciting complement-dependent cytotoxicity in test samples, including human serum.

The AttoPhos® AP Fluorescent Substrate System provides a highly sensitive fluorescent alkaline phosphatase substrate.   The system includes AttoPhos® Substrate, AttoPhos® Buffer and Calibration Solution. AttoPhos® Substrate (2′-[2-benzothiazoyl]-6′-hydroxybenzothiazole phosphate [BBTP]) is cleaved by alkaline phosphatase to produce inorganic phosphate (Pi) and the alcohol, 2′-[2-benzothiazoyl]-6´-hydroxybenzothiazole (BB…

The Glutamate-Glo™ Assay is a bioluminescent assay for rapid, selective and sensitive detection of glutamate in biological samples.

The Glutamine/Glutamate-Glo™ Assay is a bioluminescent assay for rapid, selective and sensitive detection of glutamine and glutamate in biological samples.

The Succinate-Glo™ JmjC Demethylase/Hydroxylase Assay is a bioluminescent assay for detecting the activity of JumonjiC (JmjC) histone demethylases and many Fe(II)/α-ketoglutarate-dependent dioxygenases that use α-ketoglutarate as substrate and release succinate as a product.

Count on minimal interference from test compounds when screening your compound library using luminescent, ATP-based kinase assays. We offer the ADP-Glo™ Kinase Assay, Kinase Selectivity Profiling Systems and hundreds of Kinase Enzyme Systems. These sensitive, reliable assays are easily scaled to meet your throughput needs and can be used with virtually any kinase and kinase substrate combination.

Directly Measure HDAC-Test Compound Affinity and Residence Time in Live Cells

BRET-Based Assays to Detect Protein:Protein Interactions in Live Cells

Developing a precise, accurate, and reliable assay is never easy. From raw material sourcing, to technical considerations, to optimization and ultimate scale-up, a development team counters challenges that strain resources and delay timetables. Savvy developers recognize that assay development and optimization move smoother when optimal raw materials and expert support are identified early in the process.

Multiplate live-cell analysis system

COMET™ is a fully automated, high-throughput, hyperplex platform for the analysis of Formalin-Fixed, Paraffin-Embedded (FFPE), and frozen tissues.

Tools to acelerate biomarker identification and validation

Calculate drug toxicity and safety endpoints

Neurofilament light (NF-L) is a 68 kDa cytoskeletal intermediate filament protein that is expressed in neurons. It associates with the 125 kDa Neurofilament medium(NF-M) and the 200 kDa Neurofilament heavy (NF-H) to form neurofilaments. They are major components of the neuronal cytoskeleton, and are believed to function primarily to provide structural support for the axon and to regulate axon diameter. Neurofilaments can be re…

HD-X Analyzer

ARRALYZE 8 Chamber Slide combines standard slide format with advanced nanowell technology, featuring 8 chambers with 127 precisely etched nanowells (0.4 × 0.4 × 0.225mm) per chamber. The borosilicate glass bottom (0.175μm thick under wells) provides superior optical clarity for high-resolution imaging while maintaining an inert environment. Includes 3 fiducials per chamber for easy navigation and precise cell tracking.

Isotope labeled products for Bio-NMR studies

Monoclonal Anti-Claudin-18.2 Antibody, Mouse IgG1 (3B10) was developed to be exquisitely CLDN18.2 specific, characterized as not cross-reacting with CLDN18.1 and without background staining.

In breast cancer STC2 is induced by estrogen and STC2 expression levels correlate with levels of estrogen receptor. STC2 function in different cancers may involve regulation of cell proliferation, neoplastic transformation and endothelial invasion. STC2 also plays a role in epithelial-mesenchymal transition by activation of MAPK/ERK signaling in hypoxic ovarian cancer cells. 

The EUROLabWorkstation ELISA provides fully automated processing of ELISA in laboratories with high sample throughput. The system has a high capacity of up to 15 microplates and can process more than 200 tests per hour. Ten washable needles, complementary accessories and a separate robotic arm for handling the microplates enable unparalleled sample throughput. Intuitive software guides the user through all work steps.