Reference Materials/Research Services Products & Reviews

This immunodeficient nude mouse originated from NIH and was originally thought to be a BALB/c congenic. It was later determined that it was not inbred and is therefore maintained as an outbred. It is not associated with any stock or strain. The animal lacks a thymus, is unable to produce T cells, and is therefore immunodeficient. To Charles River from NCI in 2010. Model Properties: Coat Color: Hairless, albino background…

This Snap-N-Spike® reference solution is suitable for use in urine drug testing, clinical toxicology, or forensic analysis by LC-MS/MS or GC/MS.

Certified reference material, 8000 μg/mL in pyridine

Certified reference material, 1000 μg/mL in pyridine, ampule of 5 mL

Tests 5 physical parameters of virtually all tablet shapes

In vivo model for cardiovascular, alzheimer’s and other neurodegeneration studies. Apolipoprotein E (ApoE) is a critical apoprotein of the chylomicron which binds to a specific receptor on liver cells and peripheral cells. Defects in ApoE result in disrupted transportation of lipoproteins, fat-soluble vitamins and cholesterol into the lymph systems, and then into blood.ApoE Knockout Rat Characteristics: 16 bp deletion wit…

CAS SciFinder -  The First Choice With SciFinder from CAS, you can increase your productivity and achieve faster breakthroughs Advancing the pace of research, Chemical Abstracts SciFinder search allows you to get results fast without compromising precision and accuracy. CAS SciFinder allows you to explore a wealth of information using sophisticated search and analysis technology. Chemical Abstracts SciFinder is a research d…

PT samples have to be right. Your laboratory’s accreditation is at stake, so anything less than 100% confidence is just not good enough. That’s why we bring over 25 years of multidisciplinary reference material manufacturing and certification experience into every step of our process. And that’s why our analytical validation specifications are more stringent than the current TNI standards.

We offer ISO-accredited microbiological certified reference materials. Validated and traceable cultures are no more than two passages from the primary reference culture ensuring genetic traceability to the primary cell line. Each lyophilized culture is preserved in our proprietary Microgel-Flash™ quick dissolve matrix. Pellets dissolve instantly once hydrated. Manufactured and tested under ISO 17034 and 17025 accreditations.

PFAS testing can be highly challenging which is why we make it easier with our convenient portfolio of PFAS reference materials. Advance environmental and health safety with standards you can trust.

The World’s First Microplastics Reference Materials. Our scientists have focused on these emerging global threats, and are excited to share Chiron MicroPrefs®, the first commercial microplastic reference material portfolio is designed to detect the six most abundant plastics in the environment and is available in a novel, easy-to-use tablet formulation.

We proudly provide the Industry with quality, accuracy, ease of use, and an extensive offering for all your testing needs! Spex®, NSI, and Chiron offers ISO 17034 Certified Reference Materials (CRMs) for all of the common contaminants such as pesticide residues, residual solvents, and heavy metals, as well as qualitative analysis CRMs.

Pursue preliminary appraisal of your drug candidate's safety with Covance's Lead Optimization (LO) Toxicology services. Whether your screening needs are for traditional dosing and observation methods or technologically sophisticated services, Covance LO Toxicology services, Safety Assessment and Abuse Liability provides you with sophisticated preclinical measurements of cardiovascular, endocrine, behavioral or neural function…

Capitalize on the intricacies of research questions honed over thousands and thousands of in vivo pharmacology studies conducted by Covance. Procure Covance's in vivo pharmacology expertise and capabilities for your benefit in the design, validation, conduct, and analysis of animal efficacy pharmacology studies for your drug candidates.Lead Optimization Pharmacology Service Features: Assessing and engaging the target tiss…

Obtain critical pharmacokinetic, pharmacodynamic and toxicokinetic assessments with Covance PK/TK Analysis services. Analysis of pharmacokinetics, pharmacodynamics and toxicokinettics data is a critical element in both the preclinical and clinical development of new drugs. Covance retains a dedicated team of highly experienced pharmacokineticists who know how to support your preclinical and clinical studies.PK/TK Analysis Ser…

Ready 4 Action, proprietary feasibility assessment, sets the cornerstone of a cost-effective product development plan. Ready 4 Action is the four-step process used to evaluate the viability of proposed drug products. This important tool enables clients to make the go/no-go decision regarding a given drug's market potential and clinical development feasibility.Armed with the neccessary intelligence, uncover with Ready 4 Action…

Industry’s Most Capable Big Data Big Analytics Platform - Bringing scale and speed to Big Data Big Analytics using the R Language Revolution R Enterprise is the fastest, most cost effective enterprise-class big data big analytics platform available today. Supporting a variety of big data statistics, predictive modeling and machine learning capabilities, Revolution R Enterprise is also 100% R. Revolution R Enterprise provides…

Camargo ensures the appropriate regulatory requirements are met every step of the way, streamlining your drug development process all the way to approval.Ready to guide you through the preclinical stage of drug development, Camargo provides strategic support in the following areas: CRO selection Study design Study setup and execution Project management In clinical program development, camargo's focus is unwavering:…

Comprehensive Clinical Development Services Camargo's knowledgeable pharmacokineticists work diligently to determine the proper PK study designs needed to support a successful clinical drug development plan while avoiding unnecessary and costly studies. Expertise includes Phase I PK data analyses — both compartmental and non-compartmental — and interspecies scaling for first-time studies in humans. In addition, our PK staff h…

Hepregen offers a range of DMPK services using their HepatoPac™ co-culture system. Hepregen has experienced scientific staff which work closely with our clients to design assays that meet their needs. We take great pride in our quality results and impeccable customer care. If you don't see your application of interest, our scientists can work with you to create a custom assay.DMPK Services: Metabolite Identification Intr…

Hepregen offers a range of toxicology services using their HepatoPac™ co-culture or Kupffer Cell Model systems. Hepregen's experienced scientific staff work closely with clients to design assays to meet their needs. Hepregen take great pride in their quality results and impeccable customer care. If you don't see your application of interest, their scientists can work with you to create a custom assay.Toxicology Services:…

The 11BHSD2 mouse was produced by injection of a construct, containing 11β-HSD2 cDNA isolated from mouse kidney and cloned into plasmid Clone 26 to recruit the 5.4 kb mouse α–myosin heavy chain (α-MHC) promoter, into pronuclei of C57BL/6 embryos. Transgenic mice were maintained by sibling mating and used as hemizygotes. Model Properties: Coat Color: Black Ideal For: Cardiac hypertrophy, heart failure Strain Code: 510 HE,…

Developed by C.C. Little in 1921, from a mating of Miss Abby Lathrop’s stock that also gave rise to strains C57BR and C57L. Strains 6 and 10 separated about 1937. To Hall in 1948 from The Jackson Laboratory. To NIH in 1951 from The Jackson Laboratory at F32. To Charles River in 1974 from NIH. Model Properties: Coat Color: Black MHC Haplotype: H2b Ideal For: general multipurpose model, diet-induced obesity, transgenic…

Silvers and Billingham began brother x sister matings with selection for histocompatibility in 1958 from a brown mutation in a stock of wild rats maintained by King and Aptekman in a pen-bred colony of rats trapped from the wild in 1930 by King at the Wistar Institute. To Charles River from Radiobiology Institute, Netherlands in 1976. Model Properties: Coat Color: Non-agouti brown MHC Haplotype: RT1n Ideal For: Geneti…

The New Zealand White rabbit was obtained in 1991 by Charles River Canada (CRC) from Kitayama Labs K.K. of Nagano Prefecture, Japan. Model Properties: Coat Color: White (albino) Ideal For: General multipurpose model Strain Code: 052