Cogent Diamond Hydride™ HPLC Columns
Cogent Diamond Hydride HPLC Columns are manufactured with TYPE-C™ silica (silica hydride) and a very small amount of carbon on the surface that adjusts the column hydrophobicity to an important level. This makes these columns have unique separation capabilities for scientists working in LCMS, metabolomics, bioanalytical, amino acids, organic acids, carbohydrates, and very polar small molecules.
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LCMS
In our experience, the Cogent Type C columns have provided a broad range of selection capabilities. The fact that separations in both the reversed-phase and aqueous normal phase modes are possible on the same column is a very useful feature. The retention and separation capabilities of hydrophilic compounds are particularly notable. The versatility, durability and rapid equilibrium of the Type C columns for most applications is superior to typical HILIC columns. A comprehensive review of the Diamond Hydride and other Type C columns can be found it the following article: Trends in Analytical Chemistry, Vol 42, 2013, 64-73.
Review Date: 6 Oct 2015 | MicroSolv Technology Corp.
Polar Compounds In Tobacco Testings
Cogent Diamond Hydride HPLC Column is good for retention of small polar compounds from complex sample matrices. Mobile phases are compatible with LC-MS/MS methods.
Review Date: 24 Oct 2014 | MicroSolv Technology Corp.
The Cogent Diamond Hydride Columns provide excellent Selectivity, Faster Equilibration and Robust Column lifetimes. These columns are chosen for analysis of polar compounds that are difficult to retain in Reversed Phase methods.
- Extremely Precise Column to Column
- Very Fast Equilibration
- Useful for Polar & Non Polar Molecules
- Low Salt used in methods
- NOT HILIC
Precise methods have been easily developed even with complex sample matrices including biological fluids such as plasma, urine, saliva, and other matrices.
