Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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ROCK IMAGER®

FORMULATRIX®, Inc.

Crystal Clear Imaging. Unparalleled Speed. ROCK IMAGER ® - Crystallization Imagers are a series of automated imaging systems designed for protein crystallization screening. Capture superior quality images of your protein drops while learning critical information about your crystals. ROCK IMAGERs are available with various plate capacities and imaging features, so there is a model to fit every lab's budget and workflow.

4.0/5.0
|5 Reviews
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Super Duncan Thermal Cycler

Kbiosystems

KBiosystems DT-24 and DT-108 Thermal Cycling PCR systems are an alternative way of carrying out medium and high throughput PCR protocols on DNA replication and incubation to micro well format plates. Conventionally peltier heat transfer units have been used to carry out these operations, these however can prove costly to increase productivity throughput and do not optimise the yield potential of carrying out such thermal op…

4.2/5.0
|2 Reviews
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P-1000 Next Generation Micropipette Puller

Sutter Instrument Co.

Developed through years of experience with the Flaming/Brown style micropipette pullers and infused with leading edge technology, Sutter is proud to introduce the P-1000 micropipette puller. The most obvious new feature is the color touchscreen display that provides an intuitive and full-featured interface. Key Features: Color touch-screen interface Safe heat mode to protect and extend filament life Line repeat mode sim…

4.5/5.0
|5 Reviews
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P-2000 Laser Based Micropipette Puller

Sutter Instrument Co.

A significant advance in the technology of fabrication of micropipettes, optical fiber probes, and nanospray tips, is offered with the P-2000 micropipette puller. The P-2000 integrates a CO2 laser-based heat source with the technology derived from our extensive experience with conventional pullers. This system offers capabilities unmatched by other pullers. Key Features: Capable of pulling quartz, borosilicate and alumino…

3.7/5.0
|1 Review
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BV-10 Microelectrode Beveler

Sutter Instrument Co.

Elegant and simple to use, the BV-10 offers precision beveling of micropipette tips between 0.1 and 100µm. The unique abrasive plate drive system is vibration free for greater control of the beveling process. Beveling can be accomplished very rapidly and produces consistent tip diameters using the techniques as described by Brown and Flaming, Science, August 1974, Vol. 185. Intracellular recording electrodes can benefit from…

3.7/5.0
|1 Review
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Analytical TableTop Microscope TM3000

Hitachi High Technologies America, Inc.

It's simplicity enables all users, even those new to Electron Microscopy (EM), to image their samples and to obtain high quality, high resolution images within minutes. No special sample preparation such as coating with metal films is required for hydrated, oily or non-conducting samples, and TM3000 is easy to use like a digital camera. The TM3000 TableTop Microscope has been developed to cover the widest range of industrial a…

4.4/5.0
|2 Reviews
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SU6600 Analytical VP FE-SEM

Hitachi High Technologies America, Inc.

The SU6600 is Hitachi's latest high resolution analytical field emission SEM with Variable Pressure technology allowing observation and analysis of any type of wet, oily or dirty sample. Advanced Schottky electron gun technology combined with our patented ADAPT, automated differential aperture system, yields greater than 200nA of current; ten times the current other manufacturers can provide with thermal emissions. The large a…

3.7/5.0
|1 Review
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Fluorescence Spectrophotometer F-2700

Hitachi High Technologies America, Inc.

The Hitachi F-2700 Fluorescence Spectrophotometer is available in two configurations depending on your laboratory’s needs: stand-alone and PC-controlled. As a stand-alone unit using the built-in keyboard and LCD screen, it is ideal for teaching and routine measurements. Adding PC control expands its capabilities to advanced applications in biotech research and materials research. With a LCD screen, it is ideal for teaching and…

4.4/5.0
|5 Reviews
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Double Beam Spectrophotometer UH5300

Hitachi High Technologies America, Inc.

Use of long-life xenon flash lamp Light source is guaranteed for seven years*1 resulting in lower operation cost Double-beam optical system Ensures extended periods of data stability compared with the single-beam optical system. Best-of-class levels*2 of resolution of 1 nm have been achieved. Operation by use of tablet terminals or PC, Simple and intuitive user interface Remote control through wireless com…

4.3/5.0
|1 Review
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Hitachi U-2900/U-2910 UV-Vis Double Beam Spectrophotometer

Hitachi High Technologies America, Inc.

The U-2900 is a double-beam spectrophotometer offering high performance, ease of use, and reliability. This system can be used in many applications from routine to research. U-2900 Features • The U-2900 is equipped with a Large Keyboard • Photometric modes include Absorbance, % T, and Concentration • Wavelength range from 190 - 1100nm • Scan Speeds of 10, 100, 200, 400, 800, 1200, 2400 and 3600nm/min (selectable in UV Solution…

4.4/5.0
|6 Reviews
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Hitachi U-4100 UV-Vis-NIR Double Beam Spectrophotometer

Hitachi High Technologies America, Inc.

The Hitachi U-4100 provides High-Performance, Double-Beam, Double-Monochromator Spectroscopy System for UV-Visible-NIR regions Features • Offers enormous flexibility for the evaluation and quality control of a wide variety of optical components over a wavelength range of 175-2600 nm • Available with prism/grating or grating/grating double monochromator system configurations with standard (200 x 200 mm) or large sample compartm…

4.0/5.0
|1 Review
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Mastercycler® Series

Eppendorf

Eppendorf Mastercycler is the economical option when, after having optimized your PCR using Mastercycler gradient, you wish to carry out an experiment with the usual Mastercycler quality, but without blocking your optimization cycler.The entire Eppendorf Mastercycler family boasts the personal card system. Chip-based memory cards enable not only simple and reliable transfer of your individual protocols between different Master…

4.5/5.0
|24 Reviews

twin.tec PCR Plate 96 and 384

Eppendorf

Eppendorf® twin.tec PCR plates give you the advantages that come from combining two materials: the wells are manufactured from virgin polypropylene, the most successful material used for PCR tubes; polycarbonate, an especially rigid material, forms the plate deck and the skirt. This one-piece design is achieved by an innovative injection moulding process, twin-shot technology. Polycarbonate enhances the mechanical stability an…

4.4/5.0
|2 Reviews

Biochrom 30+ Amino Acid Analyzer Physiological system

Biochrom Ltd

The Biochrom 30+ Amino Acid Analyzer is trusted by hospitals, reference labs, pharmaceutical and industrial labs worldwide. It accurately detects and quantifies amino acids and their derivatives in complex samples. Applications include: detection and monitoring of in-born errors of metabolism, PKU testing, clinical analysis, proteomics, drug synthesis, infusion fluids, and quality control. The system is based on cation exc…

3.5/5.0
|2 Reviews

Finnigan TSQ Quantum Series

Thermo Fisher Scientific

The Finnigan TSQ Quantum Series of mass spectrometers are the most advanced and powerful triple quadrupole mass spectrometers available. The Quantum Series mass spectrometers feature the patented HyperQuad™ mass analyzer technology, a rugged orthogonal source, and a completely redesigned analyzer geometry for maximum sensitivity, precision, and reliability. The Quantum Series triple quads are the only commercial triple quads a…

4.3/5.0
|13 Reviews

Finnigan™ LTQ FT MS™

Thermo Fisher Scientific

This advanced, high performance ion trap - Fourier Transform mass spectrometer is the right tool for your toughtest analytical challenges in metabolic studies, proteome analysis, pharmaceutical discovery, and all other applications. Product detail: The Finnigan LTQ FT™ combines the most advanced Ion Trap and Fourier Transform Ion Cyclotron Resonance technologies into a single instrument with unprecedented analytical power…

4.0/5.0
|6 Reviews

Access™ Laboratory Workstation

Small-Scale Automation with Large-Scale Results   Access™ laboratory workstations multiply the benefits of the Echo® liquid handler by improving overall assay throughput and reproducibility. With the ability to integrate a variety of devices and the modularity to scale when needed, each workstation offers the flexibility required by frequently-changing assay requirements.  All Access workstations are optimized at install and i…

4.1/5.0
|7 Reviews

Magna ChIP™ Protein A Magnetic Beads

Merck

Recombinant protein A covalently bound to magnetic beads. These beads provide users a rapid, reproducible and efficient reagent for collecting immunocomplexes for chromatin immunoprecipitations (ChIP) assays. Compared with conventional protein A agarose beads, protein A magnetic beads significantly reduce the handling time and mechanical stress on target immunocomplexes.

4.3/5.0
|1 Review

Anti-Citrulline (Modified) Detection Kit

Merck

This kit provides the reagents required for the detection of citrulline-containing proteins by Western blot analysis with the anti-Citrulline antibody. Detection is a two-step process in which citrulline-containing proteins immobilized on nitrocellulose or PVDF are formaldehyde-cross linked to the membrane to improve protein retention, followed by modification of citrulline residues with 2,3-butanedione monoxime and antipyrine…

4.3/5.0
|1 Review

ChIPAb+ EZH2, clone AC22

Merck

The ChIPAb+ EZH2, clone AC22 antibody/primer set includes the EZH2, clone AC22 antibody, a negative control antibody (purified mouse IgG), and qPCR primers which amplify a 135 bp region within the promoter of the human MYT-1 gene. The EZH2, clone AC22 antibody and negative control antibodies are supplied in a scalable "per ChIP" reaction size and can be used to functionally validate the precipitation of EZH2-associated chromat…

4.3/5.0
|1 Review