Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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LabScan XE Spectrophotometer

HunterLab

Measures Color the Way You See ColorTo maintain maximum measurement stability, LabScan XE automatically checks and adjusts to an internal reference standard. To accurately measure optically brightened materials, ultraviolet calibration and control of the illumination source is available.Use LabScan XE to measure samples in virtually any form including solids, powders and liquids. The system can be used in sample port-up, port-…

4.3/5.0
|1 Review

Crystal Screen

Hampton Research

The Crystal Screen and Crystal Screen 2 reagent kits are designed to provide a highly effective and rapid screening method for the crystallization of macromolecules. The screens are simple and practical for finding initial crystallization conditions. The initial crystallization conditions for more than 1,000 proteins, peptides, oligonucleotides, and small molecules have been determined using Crystal Screen.A highly effective…

4.3/5.0
|1 Review

Structure Screen 1

Molecular Dimensions

Originally published in 1991 by Jancarik & Kim from conditions found to be successful in the crystallization of biological macromolecules. This classic standard sparse matrix screen lets you: Determine initial crystallization conditions. Establish the solubility of a macromolecule in a varying range of pH and precipitants. and with the enhanced buffer selection enables screening of greater crystallization space.Structure Scre…

4.2/5.0
|2 Reviews

PEG/Ion

Hampton Research

PEG/Ion, developed by Hampton Research, is a crystallization screen designed to evaluate monodisperse, high purity Polyethylene glycol 3,350 and 48 unique salts representing a very complete range of anions and cations frequently used in the crystallization of biological macromolecules. The primary screening variables are PEG, ion type, ionic strength, and pH. More than 60% of the published crystallizations utilized PEG as a p…

4.0/5.0
|1 Review

SaltRx

Hampton Research

SaltRx was developed by Hampton Research as a primary and secondary, salt and pH based crystallization screen for biological macromolecules. Salt is the only primary crystallization reagent (precipitant) utilized. Based on a design of 96 conditions, the screen evaluates a broad portfolio of crystallization salts of varying concentration and pH.SaltRx can be used as a primary crystallization screen when salt, ionic strength an…

4.3/5.0
|1 Review

Index Crystallization Screen

Hampton Research

Index is designed as a 96 reagent crystallization screen that combines the strategies of the grid, sparse matrix, and incomplete factorial screening with traditional, contemporary, and new crystallization reagent systems into a highly effective and efficient format. Index, as the name implies, efficiently samples a series of specially formulated reagent zones to identify which reagent class or classes and pH are effective in…

4.1/5.0
|3 Reviews

Eppendorf DASGIP® Parallel Bioreactor System

Eppendorf

DASGIP Parallel Bioreactor Systems for R&D and process development in both cell culture and microbiology allow for advanced bioprocess control and automation. Parallel processing, precise control of all relevant parameters, user-defined profiles and innumerable automation features result in accelerated and highly efficient process development. Our DASware software solutions support DoE, process historians and comprehensive…

3.7/5.0
|2 Reviews

Eppendorf New Brunswick™ BioFlo®/CelliGen® 510

Eppendorf

BioFlo 510 Fermentors and CelliGen 510 Bioreactors are intermediate systems ideal for pilot to small scale production processes. The modular design features a wide variety of standard options allowing this system to be flexible enough to meet most process requirements.   Eppendorf New Brunswick™ BioFlo®/CelliGen® 510 Working volumes: 10.75 L to 32.0 L Applications: Laboratory and pilot scale fermentat…

4.3/5.0
|1 Review

SPECTRONIC™ 200 Spectrophotometer

Thermo Fisher Scientific

Thermo Scientific™ SPECTRONIC 200 is the new standard for rugged, simple-to-use visible spectrophotometers for teaching and routine applications. The new SPECTRONIC 200 spectrophotometer couples the simplicity and reliability of the SPECTRONIC 20 and GENESYS 20 instruments with 21st century technology and a bold new design that promises years of trouble-free performance.The system is a rugged, simple-to-use spectrophotometer…

4.3/5.0
|1 Review

Falcon® 875cm² Rectangular Straight Neck Cell Culture Multi-Flask, 5-layer with Vented Cap

Corning Life Sciences

Increase productivity by enabling to grow more cells faster and easier. 3- or 5-layer formats provide 525 cm2 and 875 cm2 cell growth surface area, respectively.Even distribution of media across all layers for homogeneous cell growthAbility to mix cells and reagents in the Falcon Multi-Flask saves time and reduces risk of contaminationFlexible design allows to pour or aspirate/recover cells using a pipetConsistent surface trea…

4.0/5.0
|1 Review

nanoLiter Cool Wave Dispenser

nanoLiter LLC

nanoLiter Cool Wave Dispenser - Major sensitivity and repoducibility increases for ESI & MALDI Nanoliter dispensing devices can be used to place media on the MALDI plates for MALDI/TOF instruments, but the most exciting ability of this device is to collimate droplets directly into the ion source like electrospray (ESI), the unique concept being that nearly 100% of the droplets go directly into the source versus <1% from ESI,…

4.3/5.0
|1 Review


Grid Screen Ammonium Sulfate Individual Reagents

Hampton Research

Individual reagents from the Grid Screen Ammonium Sulfate and Grid Screen Salt HT screens. Grid Screen Ammonium Sulfate Individual Reagents Features: 185 ml volume Sterile filtered Applications: Individual Grid Screen Ammonium Sulfate and Grid Screen Salt HT screen reagents for screening, optimization and production

3.7/5.0
|2 Reviews

Zensor TE100 SPEs

eDAQ, Inc.

These Zensor screen printed electrodes (SPEs) feature a carbon working electrode (central circle), carbon auxiliary (outer annular crescent) and Ag/AgCl pellet reference electrode. They can be used as low cost disposable electrodes in aqueous solutions of moderate pH. Disposable SPEs can be used as an alternative to expensive glassy carbon or platinum electrodes for teaching experiments, or routinine analyses, where a clean r…

3.7/5.0
|1 Review

PACBIO RS II

Pacific Biosciences

The PacBio RS II is a Single Molecule, Real-Time (SMRT®) DNA Sequencing System that provides the highest consensus accuracy and longest read lengths of any available sequencing technology. SMRT Sequencing is ideal for de novo assembly, characterization of genetic variation, methylation analysis, microbiology studies, and more.The instrument features high performance optics, automated liquid handling, and an environmental cont…

3.9/5.0
|4 Reviews

CLC Genomics Workbench

CLC bio

Dominating the high-throughput sequencing data analysis challenge We have overcome the challenge to analyze high-throughput sequencing data faster than it is produced by implementing a SIMD-accelerated assembly algorithm in our next generation sequencing solution, CLC Genomics Workbench – a cross-platform desktop application with a graphical user-interface. CLC Genomics Workbench, for analyzing and visualizing next generation…

4.3/5.0
|1 Review

KAPA2G Robust PCR Kits

Kapa Biosystems, Inc.

Streamline your PCR workflows by consolidating protocols and reaction conditions, increase pass rates, amplify difficult templates without bias, and increase sensitivity – all with a single enzyme. The second-generation KAPA2G Robust DNA Polymerase was evolved to solve - achieve consistent amplification across a broad range of amplicon types (both GC and AT-rich). The versatility and robustness of the polymerase allows for con…

3.7/5.0
|1 Review

Megaruptor®

Diagenode

Diagenode’s ultimate solution for long fragment library preparation between 2kb and 75kb– the Megaruptor® fragmentation system. A number of applications for massively parallel sequencing, also known as Next-Generation Sequencing, require libraries of long DNA segments, but few methods have been available for reliably generating fragments greater than 2 kb. The Megaruptor, which has been used by several sequencing centers w…

4.0/5.0
|1 Review

20-22 Isotope Ratio Mass Spectrometer

Sercon

Combining superior analytical performance with class leading reliability, the 20-22 ensures that all your scientific needs are met. Backed by over 20 years of development with a no compromise approach to its engineering integrity, Sercon provides the ultimate isotope ratio mass spectrometer. This technology is available in both continuous flow 20-22 and dual inlet GEO 20-22 forms to be interfaced with our range of automated p…

4.3/5.0
|1 Review

Wizard® Plus Minipreps DNA Purification Systems

Promega Corp.

The resin-based Wizard® Plus Minipreps DNA Purification System provides a simple and reliable method for rapid isolation of plasmid DNA.   When using the standard protocol, the entire miniprep process can be completed in 15 minutes or less, with no organic extractions or ethanol precipitations. Minipreps may be processed individually or in multiples with the Vac-Man® (20-sample capacity, Cat.# A7231) or Vac-Man® Jr. (2-s…

4.0/5.0
|2 Reviews

Fast ID Genomic DNA Extraction Kit

Genetic ID

Fast ID is a single, easy-to-use DNA extraction kit suitable for a variety of sample types. Fast ID provides high yields of exceptionally pure DNA from a wide variety of sample types including seeds, fruits, vegetables, plants, microbes and clinical specimens. Fast ID contains powerful denaturants and DNA-selective reagents that are specifically designed to prevent DNA degradation and to remove contaminants that might inhibit…

4.0/5.0
|1 Review

Qube High Throughput Screening System

Sophion Bioscience

The Qube is Sophion's next generation high-throughput system for ion channel screening, intended for use in laboratories with a need for thousands of data points per day. The Qube finally bridges the gap between high-throughput and high quality in ion channel assays.The Qube can be used for primary and secondary screening of any ion channel of interest. Sophion's vast experience with planar patch clamp from the QPatch products…

4.3/5.0
|1 Review

Cellometer Auto 2000 Cell Viability Counter

Cellometer Auto 2000 Cell Viability Counter for Primary Cells. The Auto 2000 utilizes bright field imaging and dual-fluorescence imaging to quickly and accurately identify and count individual cells. Cell count, concentration, diameter, and % viability are automatically calculated and reported.The Cellometer Auto 2000 is specifically optimized for analysis of primary cells from peripheral blood, cord blood, bone marrow, and o…

4.2/5.0
|8 Reviews

CellTiter-Glo® 3D Cell Viability Assay

Promega Corp.

The CellTiter-Glo® 3D Cell Viability Assay is a homogeneous method to determine the number of viable cells in 3D cell culture based on quantitation of the ATP present, which is a marker for the presence of metabolically active cells.   This ready-to-use reagent is based on the original CellTiter-Glo® Luminescent Cell Viability Assay chemistry and eliminates the need to combine buffer with lyophilized substrate when prepa…

4.3/5.0
|5 Reviews

ez-Control

Applikon Biotechnology

The ez-Control is an easy to use system for bioreactors and fermentors. The system accurately controls pH, Temperature, Dissolved Oxygen, Foam/Level and Agitation. The color touch screen interface guides the user through the operation. The adaptive control features allow the user to focus on the process while the controller keeps tight control on the important process parameters. Features: Simple operation through the c…

4.3/5.0
|1 Review