Drug discovery > Lead Discovery Products & Reviews

Powerful high-resolution benchtop MALDI-TOF MS  – 15k resolution – easy to use but ideal for many analytical challenges.

Rtx®-VMS Columns (fused silica) (proprietary Crossbond® phase) • Application-specific columns for volatile organic pollutants by GC-MS • Complete separation of U.S. EPA Method 8260B compounds in less than 10 minutes • Stable to 260 °C • No known equivalent phases

Developed specifically for using LC coupled with GC-FID to accurately determine hydrocarbons found in mineral oils, which can migrate from packaging into food. • 9-component mix contains non-interfering internal standards as well as both mineral oil saturated hydrocarbon (MOSH) and mineral oil aromatic hydrocarbon (MOAH) markers to correctly cut fractions. • Certified reference material (CRM) manufactured and QC-tested in Re…

The new generation of Eppendorf ThermoMixer® and ThermoStat incubator raise sample preparation to the next level Ever since the launch of the company’s first performance-defining Mixer and the first Thermostat in 1964 Eppendorf has been at the forefront of mixing and temperature control technology for µL volumes. Thanks to Eppendorf’s continuous development, an exciting new generation of Temperature Control and Mixing Instrume…

Clean Screen® DAU Solid Phase Extraction Column is the flagship product of the forensic solid phase extraction column line. The first product of its kind in the industry, it is a mixed-mode column exhibiting both hydrophobic and cation exchange characteristics. Over 20 years of experience has shown this column to be effective on hundreds of drugs in both the acid-neutral and basic drug categories.

The Clean Screen® XCEL Solid Phase Extraction Columns are a line of sample prep phases designed to reduce the number of steps in the extraction, and therefore the amount of time and solvent necessary to complete the sample cleanup. Further advantages include reduced sample size and improved cleanliness and recovery. The Xcel I column will extract a wide array of basic drugs including benzodiazepines and opiates. The Xcel II co…

These cartridges are designed to meet large volume, real world samples. The frits and sorbent bed resist plugging, the format fits several types of manual and automated extraction systems. Various bonded phases available including C18, C8, DVB, & graphitized carbon black.

The Clean Screen® FASt column is a novel approach to improved sample preparation for LC/MS analysis. The column employs a one step process to prepare urine samples for analysis of multiple drugs and metabolites. By quickly and efficiently reducing the amount of unwanted matrix and particulates in the final sample, the analysis can proceed with less chance of matrix suppression and LC column clogging.

Clean Screen® Xcel Well Plates The Clean Screen Xcel products are a line of sample prep phases designed to reduce the number of steps in the extraction, and therefore the amount of time and solvent necessary to complete the sample cleanup. Further advantages include reduced sample size and improved cleanliness and recovery. The Xcel I well plate will extract a wide array of basic drugs including benzodiazepines and opiates.…

Positive Pressure Manifold - A simple, robust way to quickly process up to 48 samples at one time. The Positive Pressure Manifold can accommodate a multitude of column sizes and provides even flow to each position. Positive Pressure Manifold Features: All 48 positions are individually regulated to provide even pressure to each column. There are four banks of 12 positions each. The user can control flow to each of the four…

SELECTRA-SIL® Derivatizing Reagents SELECTRA-SIL® is an extensive line of derivatizing reagents manufactured by UCT at its facility in Bristol, PA. Our reagents are designed to increase molecular weight, lower boiling points, and create a more specific ion for compounds intended for gas chromatography and GC/MS. SELECTRA-SIL® Derivatizing Reagents Benefits: Improved chromatographic resolution - increased volatility - red…

Our 96 Deep Well Plates are made from solvent resistant, low extractable polypropylene. Standard frits are polyethylene with 20μm pores. The 2mL well provides capability for methods that require a larger sample size. The separate wells and greater capacity eliminate well-to-well carry over. We offer disposable plates compatible with Beckman, Caliper, Gilson, Hamilton, PerkinElmer and Tecan liquid handling systems. 96 Deep Wel…

Endcapped C18 - Enviro Clean SPE Cartridges Enviro-Clean® cartridges are designed for use by analysts that demand a clean, dependable and rugged product for low level environmental analyses. Our EC SPE Cartridges run the gambit of our sorbents for every configuration you require. C18, Octadecyl Hydrophobic, 1000 mg/6 mL. Part # EEC181M6

Stop spending your time and money developing LC-MS/MS multi-residue pesticide methods and mixing reference standards when you could be running samples. Restek’s trusted food safety experts have already done the work for you—with guaranteed accuracy and at a lower cost. Restek’s new certified reference materials (CRMs) for LC-MS/MS multi-residue pesticide analysis eliminate the need to source, purchase, and store individual ma…

The MALDI-7090TM is targeted for proteomics and tissue imaging. It combines Shimadzu’s extensive MALDI TOF-TOF mass spectrometry expertise with novel patented technology to provide ultimate performance in identification and structural characterization of biomolecules.   Offering unparalleled MS/MS resolution and excellent mass accuracy, Shimadzu’s new MALDI-7090 tandem mass spectrometer achieves a new level of MALDI…

The Rtx®-Volatile Amine column was designed specifically for analyzing volatile amines in difficult matrices, such as water. The unique base deactivation creates an exceptionally inert surface for these sensitive compounds, resulting in highly symmetrical peaks which allow low detection limits. The stable bonded phase yields a column that is not only retentive and highly selective for these compounds, but is also very robust…

BioDrop μLITE is the only choice for micro-volume measurement when you need speed without sacrificing accuracy or precision. With no moving parts, the unique in-built sample port offers unrivalled performance delivering a dsDNA detection limit of 1ng/μL. Because the pathlength doesn’t change, the instrument provides excellent measurement reproducibility. Measurements made with the BioDrop μLITE are also highly accurate becaus…

BioDrop DUO UV/Vis spectrophotometer has two measurement modes: a unique in-built sample port unrivalled dsDNA detection limit of 1ng/μl PLUS a cuvette holder for the revolutionary BioDrop CUVETTE 125, ideal for highly concentrated samples. BioDrop DUO is quick and easy to use. It has a large capacitive colour touch screen with on-board software for data acquisition and analysis. Pre-programmed methods for DNA, RNA, oligos and…

High binding surface is capable of binding medium (>10kD) and large biomolecules that possess ionic groups and/or hydrophobic regions Binding capacity is approximately 400 to 500ng IgG/cm2 Ideal for immunoassays Without lids, lids supplied separately Total volume is 360 µL; recommended working volume of 75 to 200 µL Conforms to standard microplate footprint and dimensions

Round bottom wells with 330 µL total volume Recommended working volumes of 75 to 200 µL Nonreversable lids with condensation rings to reduce contamination Treated for optimal cell attachment Sterilized by gamma radiation and certified nonpyrogenic Individual alphanumeric codes for well identification Individually wrapped

The miVac Quattro Concentrator is suitable for use with a wide range of solvents, from volatile organic solvents through to water and some of the higher boiling point solvents. The Quattro is a centrifugal vacuum concentrator compatable for use with variety of sample formats including tubes, microplates, vials and round bottom flasks. Making it an ideal "work-horse" concentrator for the busy lab. The Quattro has more than d…

Incorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the new triple quadrupole LCMS-8050 dramatically improves analytical throughput with the ultimate in high-speed performance.   In addition, the newly designed ion source and collision cell, Heated-ESI and UFsweeper® III collision cell technology, ensure the highest levels of sensitivity and quantitative performance. Combine with Shimadzu’s wo…

High performance, versatility and ease-of-use in a compact design for efficient mass spectrometry analysis.

A Restek® LC guard cartridge in an EXP® direct connect holder is the ultimate in column protection. To help protect your investment and further extend the life of our already-rugged LC columns, Restek offers the patent-pending guard column hardware developed by Optimize Technologies.Raptor™ EXP® Guard Column Cartridges Features: Free-Turn® architecture lets you change cartridges by hand without breaking inlet/outlet fluid…

Are you familiar with SiliCycle’s heterogeneous (silica-supported) catalysts? Gathered under the SiliaCat® brand, they are made using an innovative technology. The matrix consists of organically modified silica, described as a sol-gel hybrid organic-inorganic material. The SiliaCat family is an essential tool in the chemical manufacturing industry, as it opens the door for a “Green” and environmentally friendly synthetic rout…