Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Echo® 550 Liquid Handler

Beckman Coulter Life Sciences

Imagine preparing assay plates for siRNA screening, compound screening with biochemical and cell-based assays, PCR reactions and more all on a single liquid handling platform, with no tips and no cross-contamination. Labcyte has developed new acoustic droplet ejection (ADE) parameters that deliver built-in intelligence to enable users to transfer many different fluid types from a single instrument. All Echo systems come pre-ca…

4.5/5.0
|22 Reviews

Speedwave® four Microwave Digestion Systems

Berghof Products + Instruments GmbH

Berghof 'speedwave® four' microwave digestion system - uncomplicated and straight forward digestions. Speedwave makes laboratory work easier and safer. Very easy handling thanks to the top loading concept. The entire, heavy rotor no longer needs to be lifted and placed in the microwave oven. It remains in the oven chamber and the vessels are simply inserted individually and removed again after digestion. The heated vessels…

3.7/5.0
|1 Review

MultiScreen Solubility Filter Plates

Merck

96-well filter plate designed and optimized for aqueous solubility assaysDetermining a compound's aqueous solubility has become an essential early measurement to make in the drug discovery process. Poor water solubility can cause problems in many different in vitro testing techniques leading to unreliable results and/or reproducibility problems; insoluble precipitates have been shown to cause false positives in bioassays poten…

4.2/5.0
|3 Reviews

BD LSR II System

BD Biosciences

Four-laser, 18-color benchtop flow cytometer Building on the ease of use and flexibility of the BDTM LSR, the first UV benchtop analyzer, BD Biosciences introduces the BDTM LSR II. The BD LSR II has performance, capabilities, and flexibility never seen before in a benchtop analyzer. Free up your high-performance cell sorter by moving your application(s) that require a UV laser to the BD LSR II. The BD LSR II can be config…

4.0/5.0
|16 Reviews

Echo® 555 Liquid Handler

Beckman Coulter Life Sciences

Echo® 555 liquid handler - the world's fastest acoustic dispensing platform for life science applications. The Echo® 555 liquid handler is the world’s fastest acoustic liquid handling platform for life science applications. Laboratories that demand very high throughput rely upon the Echo 555 liquid handler for round-the-clock trouble-free operation to enable the fastest discovery.The Echo 555 doubles the throughput of the Ech…

4.5/5.0
|29 Reviews


CellTox™ Green Cytotoxicity Assay

Promega Corp.

The CellTox™ Green Cytotoxicity Assay measures changes in membrane integrity that occur as a result of cell death. The assay is intended to assess cytotoxicity in cell culture after experimental manipulation. The assay system uses a proprietry asymmetric cyanine dye that is excluded from viable cells but preferentially stains the DNA from dead cells. When the dye binds DNA released from cells, its fluorescence properties are s…

4.3/5.0
|1 Review

Biomek® 4000 Laboratory Automation Workstation

Beckman Coulter Life Sciences

Biomek Liquid Handlers enable you can spend less time on manual process and more time on powerful discoveries. Beckman Coulter Life Sciences is a leader when it comes to providing solutions and support that cover the full spectrum of the NGS sample preparation workflow with reagents and automation. Throughput options allow you to choose the right solution for your laboratory.

4.3/5.0
|8 Reviews

Classic Modular Test Chamber with Modified Top

Med Associates Inc.

The Classic Modular Test Chamber with Modified Top for Mouse is used primarily for drug self-administration studies. The top modification allows for placement of animal in the test chamber with drug delivery leash or other harness system, attached. Both end walls are identical with three sturdy aluminum channels designed to securely hold any modular component. The door and rear panel are constructed of clear polycarbonate. Fro…

3.9/5.0
|2 Reviews

Kainic Acid

Tocris Bioscience.

Kainic Acid is a selective agonist of kainite receptors. It is also a potent excitant and neurotoxin. Chemical Name: (2S,3S,4S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid M.Wt: 213.23 Formula: C10H15NO4 Solubility: Soluble to 25nM in water Purity: >98% Storage: Store at room temperature

3.7/5.0
|1 Review

EyeLink II

SR Research Ltd

The EyeLink II has the fastest data rate and highest resolution of any head mounted video-based eye tracker. This exceptional data quality results in very low velocity noise, making the EyeLink II ideal for saccade analysis and smooth pursuit studies. The EyeLink II system consists of three miniature cameras mounted on a comfortable padded headband. No mirrors are used in the EyeLink II system, making it very robust and easy t…

3.7/5.0
|1 Review








CryoStar™ NX50 Cryostat

Thermo Fisher Scientific

Get optimal sectioning quality and unmatched ergonomics and safety with the Thermo Scientific™ CryoStar™ NX50, designed to accommodate the needs of the routine clinical laboratory. This manual cryostat offers a form-fitting design, with optional height adjustment, cold disinfection, and vacutome.The CryoStar NX50 Cryostat follows in the footsteps of the popular CryoStar NX70 Cryostat by offering standard features well-suited…

4.0/5.0
|1 Review

ApoE Knockout Rat

SAGE Labs

In vivo model for cardiovascular, alzheimer’s and other neurodegeneration studies. Apolipoprotein E (ApoE) is a critical apoprotein of the chylomicron which binds to a specific receptor on liver cells and peripheral cells. Defects in ApoE result in disrupted transportation of lipoproteins, fat-soluble vitamins and cholesterol into the lymph systems, and then into blood.ApoE Knockout Rat Characteristics: 16 bp deletion wit…

4.0/5.0
|1 Review

GeneMate Vortex Mixer

ISC BioExpress

With advanced Q-Drive™ technology, the GeneMate Vortex Mixer provides a smooth instant vortexing of even the largest sample sizes, including full 50ml tubes. The unique counter balance system creates maximum vortexing action, while minimizing noise and excessive vibration. This results in quieter, more efficient and longer lasting operation.GeneMate Vortex Mixer Features: 2-year full replacement warranty! Powerful motor…

4.2/5.0
|2 Reviews

Cellometer Auto 2000 Cell Viability Counter

Cellometer Auto 2000 Cell Viability Counter for Primary Cells. The Auto 2000 utilizes bright field imaging and dual-fluorescence imaging to quickly and accurately identify and count individual cells. Cell count, concentration, diameter, and % viability are automatically calculated and reported.The Cellometer Auto 2000 is specifically optimized for analysis of primary cells from peripheral blood, cord blood, bone marrow, and o…

4.2/5.0
|8 Reviews

CellTiter-Glo® 3D Cell Viability Assay

Promega Corp.

The CellTiter-Glo® 3D Cell Viability Assay is a homogeneous method to determine the number of viable cells in 3D cell culture based on quantitation of the ATP present, which is a marker for the presence of metabolically active cells.   This ready-to-use reagent is based on the original CellTiter-Glo® Luminescent Cell Viability Assay chemistry and eliminates the need to combine buffer with lyophilized substrate when prepa…

4.3/5.0
|5 Reviews


Alpha 1-2 LDplus

Martin Christ Gefriertrocknungsanlagen GmbH

Drying manifold for eight round-bottom flasks, wide-neck filter bottles or ampoule distributors. Compact, high-performance tabletop unit for effective lyophilisation of specimens in your everyday lab activities. The LDplus user interface makes the work very easy. You can choose from a wide range of configurations to adapt the freeze dryer optimally to your specific needs. The condenser temperature of -55° C enables the drying…

4.2/5.0
|2 Reviews