Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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GFP-Trap®

Chromotek GmbH

GFP -Trap® - use your fluorescence fusion as tag for biochemical studies.Curiously GFP, the most widely used labeling tag in cell biology, is rarely used for biochemical analyses. This may be due in part to limited GFP antibody availability and specificity as well as co-eluted heavy and light antibody chains that interfere with subsequent analyses.Our GFP-Trap® is a high quality GFP-binding protein coupled to a monovalent matr…

5.0/5.0
|2 Reviews

Guava® easyCyte™

Luminex

Our microcapillary flow cytometry systems are simpler to operate than traditional sheath-fluid based instruments and are far easier to maintain. They utilize small sample volumes, generate minimal waste, and have lower operating costs. As a result, easyCyte™ Flow Cytometers are uniquely amenable to on-demand use in the laboratory environment and have helped many scientists achieve insightful cellular analysis since 1998.

4.9/5.0
|3 Reviews

NEBNext® Reagents for DNA Library Preparation

New England Biolabs Inc.

NEBNext® reagents are a series of highly pure reagents that facilitate library preparation of DNA or RNA for downstream applications such as next generation sequencing and expression library construction. Available in sets, master mixes and modules, these robust reagents undergo stringent quality controls and functional validation, ensuring maximum yield, convenience and value. Advantages of NEBNext Reagents for RNA Library Pr…

4.7/5.0
|4 Reviews





Microlab® AutoLys STAR Workstation

Hamilton Company

Automation to Solve Sample Lysis Bottleneck for Molecular Biology Labs The Microlab® AutoLys STAR workstation automates sample lysis and DNA extraction. This innovative instrument improves bottlenecks for forensic scientists and other molecular biologists isolating nucleic acids from samples. The Microlab AutoLys STAR – a new hardware, software, and consumables module for the popular Microlab STAR instrument line – has been te…

4.7/5.0
|1 Review

OsteoMAX-XF™ Differentiation Medium

Merck

EMD Millipore’s OsteoMAX-XF™ Differentiation Medium is specially formulated to readily differentiate human mesenchymal stem cells into the osteogenic lineage as assessed by alizarin red and alkaline phosphatase staining. This proprietary formulation was developed using Plasticell’s CombiCultTM, a patented, bead-based, combinatorial technology specially developed for discovery of novel stem cell differentiation protocols. The u…

5.0/5.0
|1 Review


Q5® Site-Directed Mutagenesis Kit

New England Biolabs Inc.

Q5® Site-Directed Mutagenesis Kit enables rapid, site-specific mutagenesis of double-stranded plasmid DNA in less than 2 hours. The kit utilizes the robust Q5 Hot Start High-Fidelity DNA Polymerase along with custom mutagenic primers to create insertions, deletions and substitutions in a wide variety of plasmids. After PCR, the amplified material is added directly to a unique Kinase-Ligase-DpnI (KLD) enzyme mix for rapid, roo…

4.8/5.0
|4 Reviews

TransIT-X2™ Dynamic Delivery System

Mirus Bio LLC

An innovative, polymeric system for efficient delivery of plasmid DNA and siRNA/miRNA. Experience the transfection breakthrough. Achieve superior transfections with an innovative polymeric system that efficiently delivers both DNA and RNA out of the endosome and into the cytoplasm overcoming a critical barrier to nucleic acid delivery.Head-to-head comparisons against the Lipofectamine® 2000 illustrate superior or equal lucife…

5.0/5.0
|2 Reviews

BRAHMS* PCT Immunoassays

Thermo Fisher Scientific

The Thermo Scientific* BRAHMS* PCT Immunoassays are immunofluorescent assays used to determine the concentration of PCT (procalcitonin) in human serum and plasma. The Thermo Scientific* BRAHMS* PCT Immunoassays are intended for use in conjunction with other laboratory findings and clinical assessments to aid in the risk assessment of critically ill patients on their first day of ICU admission for progression to severe sepsis…

4.7/5.0
|2 Reviews

NEBNext® DNA Library Prep Master Mix Set for Illumina®

New England Biolabs Inc.

The NEBNext® DNA Library Prep Master Mix Set for Illumina® contains enzymes and buffers in convenient master mix formulations that are ideally suited for sample preparation for next-generation sequencing, and for preparation of expression libraries. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expressi…

5.0/5.0
|1 Review

NEBNext® Ultra™ DNA Library Prep Kit for Illumina®

New England Biolabs Inc.

he NEBNext® Ultra™ DNA Library Prep Kit for Illumina contains enzymes and buffers that are ideal to convert a small amount of DNA input into indexed libraries for next-generation sequencing on the Illumina platform (Illumina, Inc). The workflow of NEBNext Ultra DNA Library Prep Kit for Illumina is very user-friendly and fast with minimal hands-on time.NEBNext® reagents are a series of highly pure reagents that facilitate samp…

4.7/5.0
|2 Reviews

NEBNext® dsDNA Fragmentase®

New England Biolabs Inc.

NEBNext® dsDNA Fragmentase® generates dsDNA breaks in a time-dependent manner to yield 100–800 bp DNA fragments depending on reaction time. NEBNext dsDNA Fragmentase contains two enzymes, one randomly generates nicks on dsDNA and the other recognizes the nicked site and cuts the opposite DNA strand across from the nick, producing dsDNA breaks. The resulting DNA fragments contain short overhangs, 5´-phosphates, and 3´-hydroxyl…

4.9/5.0
|2 Reviews

NEBNext® mRNA Library Prep Master Mix Set for Illumina®

New England Biolabs Inc.

The NEBNext® mRNA Library Prep Master Mix Set for Illumina® contains enzymes and buffers that are ideally suited for sample preparation for next-generation sequencing, and for preparation of expression libraries. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expression library construction. The reagents…

5.0/5.0
|1 Review

TransIT®-293 Transfection Reagent

Mirus Bio LLC

A high efficiency, low toxicity, DNA transfection reagent optimized for 293 cellsTransIT®-293 Transfection Reagent is specifically optimized to provide exceptional transfection efficiency of plasmid DNA in HEK 293 and cell types of associated lineage. TransIT-293 provides all the attributes of the trusted TransIT series of transfection reagents: high transfection efficiency, low toxicity, serum compatibility, simplicity of use…

5.0/5.0
|1 Review


Corning® 96-well Clear Flat Bottom Polystyrene High Bind Microplate, 25 per Bag, without Lid, Nonsterile

Corning Life Sciences

High binding surface is capable of binding medium (>10kD) and large biomolecules that possess ionic groups and/or hydrophobic regions Binding capacity is approximately 400 to 500ng IgG/cm2 Ideal for immunoassays Without lids, lids supplied separately Total volume is 360 µL; recommended working volume of 75 to 200 µL Conforms to standard microplate footprint and dimensions

4.7/5.0
|1 Review


miVac Quattro Concentrator

Genevac

The miVac Quattro Concentrator is suitable for use with a wide range of solvents, from volatile organic solvents through to water and some of the higher boiling point solvents. The Quattro is a centrifugal vacuum concentrator compatable for use with variety of sample formats including tubes, microplates, vials and round bottom flasks. Making it an ideal "work-horse" concentrator for the busy lab. The Quattro has more than d…

4.5/5.0
|2 Reviews


HyPerforma™ S.U.B. TK 250L Single-Use Bioreactor

Thermo Fisher Scientific

The Thermo Scientific™ HyPerforma S.U.B. TK 250L system combines the experience of hundreds of single-use stirred-tank bioreactors used in the industry today with a state-of-the-art controller system for a turnkey bioprocessing solution.This out-of-the-box solution dramatically shortens implementation time and reduces upfront cost while providing all the advantages of our open-architecture single-use bioreactors (S.U.B.). HyP…

5.0/5.0
|1 Review

MiSeqDx System

Illumina

The MiSeqDx instrument is the first and only FDA-cleared in vitro diagnostic (IVD) next-generation sequencing (NGS) system. Designed specifically for the clinical laboratory environment, the MiSeqDx instrument offers a small, approximately 4 square feet (0.37 square meters) footprint, an easy-to-follow workflow, and data output tailored to the needs of clinical labs. In addition, the integrated software enables sample trackin…

4.9/5.0
|8 Reviews