Drug discovery > Target Discovery Products & Reviews

Tyrosine kinase inhibitor; Inhibits EGFR

Inhibits Hsp90

NF-kB, AMPK, and tyrosine kinase pathway inhibitor; Inhibits tyrosine kinase and topoisomerase II and activates PPAR?

Hedgehog pathway activator; Activates Smoothened (SMO)

RHO/ROCK pathway inhibitor; Inhibits ROCK1 and ROCK2

CSF-1 pathway inhibitor; Inhibits cFMS

PKC inhibitor

Protein kinase inhibitor; Inhibits PKA, PKC, and PKG

Hedgehog pathway inhibitor

Inhibits autophagy and heme polymerase

BET family inhibitor; Inhibits BRD2, BRD3, and BRD4

cAMP pathway activator; Inhibits cyclic nucleotide phosphodiesterases

DYRK pathway inhibitor

Activin/BMP/TGF-ß pathway activator

Activin/BMP/TGF-ß pathway activator

Tyrosine kinase inhibitor; Inhibits ABL, PDGFR, and KIT

Inhibits COX-1 and COX-2

Calcium ionophore

WNT pathway activator; Inhibits protein phosphatase PP2A

SCF/c-KIT pathway inhibitor; Inhibits c-KIT

Inducer of neural differentiation

WNT pathway inhibitor; Inhibits Porcupine

WNT pathway inhibitor; Inhibits Porcupine

WNT pathway inhibitor; Inhibits Porcupine

Serum- and BPE-free medium for human airway epithelial cells cultured at the air-liquid interface or as airway organoids