UHPLC and HPLC Products & Reviews

The ACQUITY UPLC® Evaporative Light Scattering (ELS) Detector is designed specifically for optimal UPLC®/ELS performance in a small footprint. When your analytes have poor to no UV/Vis response, or don’t ionize well by mass spectrometry, the ACQUITY UPLC ELS Detector with the ACQUITY UPLC System lets you analyze more molecules (including sugars, triglycerides, phospholipids, antibiotics, and natural products) in a single analy…

The ACQUITY UPLC H-Class PLUS Bio System delivers the benefits of UPLC's resolution, sensitivity, and throughput in a system purpose-built for the analysis of proteins, peptides, nucleic acids, and glycans.

Shimadzu's Nexera is a genuine all-around HPLC that enables various types of analysis including conventional LC, ultra fast LC and ultra high-pressure LC up to 130 MPa without compromising performance and data quality. The LC-30A Nexera delivers high-speed and high-resolution analysis without sacrificing basic performance parameters such as excellent precision, near-zero carryover, good linearity, stability and ruggedness. O…

The 2545 Quaternary Gradient Module is a four solvent, low pressure mixing gradient pump (up to 150 mL/min) that serves as a solvent delivery device for purification systems. Features: • Four solvent gradient selection • Control from MassLynx, Empower, or console allowing scale up via a familiar software interface • Interfaces to a variety of detectors and peak fraction collectors for optimum purifications • Allows UV or MS di…

UPLC Technology Extends To Two Dimensions For chromatographers who require additional capabilities to increase their speed of analysis, gain sensitivity and selectivity, and perform orthogonal separations, ACQUITY UPLC® Systems can meet these needs by controlling multiple valves and pumps for 2D separations. The resolution, sensitivity, and throughput benefits of UPLC® Technology are even more important in 2D applications. Wat…

For normal-phase chromatography, the ZORBAX product line offers a choice of bonded and non-bonded silica packings. The ZORBAX CN is a polar bonded-phase column packing used for normal or reversed-phase high performance liquid chromatography, and is less prone to fouling than silica. The ZORBAX CN can be used for separations of compounds ranging from low to high polarity and is often utilized to separate compounds that have be…

TSKgel SW-type columns for size exclusion/gel filtration analysis of antibodies and other proteins are silica-based. A hydrophilic diol-type bonded phase shields the silica surface from interacting with protein samples.

The LenS3 MALS detector offers a revolutionary approach for the measurement of molecular weight (MW) and radius of gyration (Rg) of synthetic polymers, polysaccharides, proteins, and biopolymers. A novel optical design, a unique cell-block assembly, and a new calculation methodology make the LenS3 MALS detector the first groundbreaking innovation in the light scattering technology arena in decades!

Hitachi has manufactured over 1800 Amino Acid Analyzers for over 40 years. The L-8900 is capable of analyzing physiological fluids and protein hydrolysates. If you have special requirements, the L-8900 is capable of a broad range of applications including clinical, food and pharmaceuticals. The L-8900’s unique post-column delivery design mixes the two ninhydrin reagents online just prior to amino acid derivatization which mean…

The new D-Star Instruments DFL-10 HPLC Fluorescence detector provides the sensitivity and the specificity of fluorescence detection at a price consistent with most low cost UV detectors. Sensitivity is enhanced in the DFL-10 by the new analytical flowcell that employs a unique excitation and emission geometry, a completely closed optical compartment, and a thermally stabilized system. The DFL-10 can be configured with a choice…

Coulochem® III Electrochemical Detection Platform Both Coulometric and Amperometric detection Available with DC and/or Pulse/Scan modes (or both) Compatible with all HPLC columns Ideal for methods development or routine applications requiring high-sensitivity detection of a single or small group of analytes Sensitive, flexible and exceptional stabilty

Synthetic silica, composed primarily of silicon dioxide, has become indispensable in today’s world in regard to its exceptional chemical stability. Consequently, uncountable commercial applications are now relying on synthetic silica, for instance, it is the most widely used stationary phase for chromatography. For nearly two decades, SiliCycle has been exploring silica’s great possibilities and versatility in order to chall…

Selectivity that a C18 just can't give you

Utilize the increased separation speed and resolution of the Thermo Scientific™ Vanquish™ UHPLC system to detect and quantify virtually any substance using the near-universal detection capabilities of Vanquish Charged Aerosol Detectors. The Thermo Scientific™ Vanquish™ Charged Aerosol Detector H provides enhanced linear dynamic range and accurate, consistent response to support research and method development. This detector ca…

This highly retentive, highly selective phase—unique to Restek—was developed specifically for the analysis of aldehydes and ketones as DNPH derivatives. Allure AK is a reversed-phase HPLC material that has the unique ability to separate all 13 carbonyl compounds specified in California Air Resources Board (CARB) Method #1004 using a simple acetonitrile/water gradient. Other columns require long analysis times or the use of tet…

2 μg/mL in acetonitrile, analytical standard

For perfect high-performance liquid chromatography (HPLC) results, high-performance solvents are a must. LiChrosolv ® solvents are designed to optimally support analytical HPLC, fast chromatography, and LC-MS applications. They feature high degrees of UV transmittance, low particle counts, low acidity and alkalinity, and low evaporation residue levels making them ideal for reproducible separations.

Reliable and repeatable analysis of non-absorbing components  

Hypersil APS-2 columns can be used with traditional buffers and organic additives as a weak anion exchanger for the analysis of anions and organic acids. Product detail: Hypersil APS-2 columns are a versatile aminopropyl group stationary phase which can be used in 3 modes: ion chromatography (weak anion exchanger), reversed phase and normal phase chromatography. Hypersil APS-2 columns can be used with traditional buffers a…

ACQUITY UPLC® BEH HILIC columns contain the rugged 1.7 μm unbonded BEH particles and are designed to retain and separate very polar basic compounds.These unique columns are optimized and tested to produce efficient and reproducible separations under UPLC® HILIC conditions. ACQUITY UPLC BEH HILIC columns overcome a major weakness of HILIC stationary phases: chemical stability. The unbonded silica stationary phases often used in…

Exceptional Resolution of Oligonucleotide Mixtures

Axcend® provides high-performance liquid chromatography (HPLC) systems designed to be easily moved to various testing locations or placed in close proximity to other instruments for optimal coupling, such as with mass spectrometry (MS). Its small footprint saves lab space and the performance of our portable HPLC matches the performance of larger, more expensive instruments.  Reduction in size allows simpler operation, lower…

Markes’ stainless sorbent tubes are available in two sizes: 3.5” x ¼” (industry-standard), and 4.5” x 6mm (DAAMS). Industry-standard tubes are compatible with Markes, PerkinElmer, Shimadzu, Dani, CDS and Gerstel 3.5+ thermal desorption (TD) systems.

Novel sample and data transfer network system

This new strong anion exchange resin offers an optimised macro-porous structure that ensures an efficient purification of large biomolecules, such as adeno-associated viruses (AAVs) and plasmid DNA (pDNA). With its high binding capacity for such molecules and high separation efficiency even at elevated flow rates, MacroSep IEX Q is a perfect addition to DSP platforms.