UHPLC and HPLC Products & Reviews

AdvanceBio Peptide Plus columns are reversed phase, superficially porous particle LC columns optimized for the separation of target peptides, impurities, and post translational modifications.

The 1260 Infinity III Prime Analytical-Scale LC Purification System is a versatile preparative high-performance liquid chromatography (HPLC) instrument. This system offers the highest functionality and operational convenience for analytical-scale HPLC purification and entry-level quaternary UHPLC at pressures up to 800 bar and for flow rates up to 5 mL/min.

The 1260 Infinity III Prime Bio Analytical-Scale LC Purification System is a versatile preparative high-/ultrahigh-perfomance liquid chromatography (HPLC/UHPLC) system for bioseparations. The system offers outstanding functionality and operational convenience for bioanalytical HPLC and entry-level quaternary bio UHPLC at pressures up to 800 bar and flow rates up to 5 mL/min.

The 1260 Infinity III Bio-Inert Analytical-Scale LC Purification System is a dedicated solution for purifying large biomolecules in biological samples, including monoclonal antibodies and proteins.

The 1290 Infinity III Bio Analytical-Scale LC Purification System is an ultrahigh-performance liquid chromatography (UHPLC) system, configurable with a binary or quaternary pump and consisting of biocompatible material for use in biopharma (such as for critical quality attributes).

Agilent NISTmAb is a reference mAb standard that is intended for system suitability testing, establishing method, instrument, or site-to-site variability, and troubleshooting mAb CQA workflows.

Designed to withstand 100% aqueous conditions and increased retention for polar molecules, InfinityLab Poroshell 120 Aq-C18 columns are the modern and reliable choice for HPLC and UHPLC separations. Now master your polar molecules, especially under water.  

100Å pore size, high ligand density;  available in 1.0, 2.0,  3.0, 4.6 and 10 mm ids;  30 - 250 mm lengths. Pursuit columns are ideal for pharmaceutical applications using LC/MS, from analyzing lead compounds and biological samples in drug discovery, to implementing dependable analysis of raw materials and approved drugs in the QC process.  Build on the large 200A pore size silica, high liquid density delivers up to 40% faster…

The 1290 Infinity III Evaporative Light Scattering Detector (ELSD) is ideal for reproducible, sensitve detection of both volatile and nonvolatile compounds that cannot be detected by UV. A unique peltier cooled evaporator coupled with an original gas flow design allow subambient operation down to 10 °C. This delivers maximum sensitivity for compounds with significant volatility below 30 °C.

200A pore size;  available in 3.0 and 4.6  mm ids, and lengths from 50 - 250 mm. Pursuit columns are ideal for pharmaceutical applications using LC/MS, from analyzing lead compounds and biological samples in drug discovery, to implementing dependable analysis of raw materials and approved drugs in the QC process.  Build on the large 200A pore size silica, high liquid density delivers up to 40% faster separations without sacrif…

Agilent Bio-Monolith HPLC columns provide high resolution and rapid separations of antibodies (IgG, IgM), plasmid DNA, viruses, phages and other macro biomolecules. The product family offers strong cation exchange, strong and weak anion exchange, and Protein A phases.

"Extend-C18 columns incorporate a unique patented bidentate silane, combined with a double-endcapping process that protects the silica from dissolution at high pH - up to pH 11.5. Columns are best applied for separations of compounds that are either (1) basic and have little or no retention at low or intermediate pHs, (2) more stable or more soluble at high pH, or (3) basic and show poor peak shape at low or intermediate pH.…

ExionLC AE system provide full integration, control and compatibility with SCIEX mass spectrometers bringing together the speed and precision you expect for a complete solution that meets every challenge your lab faces.

The M5 MicroLC system is a feature rich microflow LC-MS solution meant to simplify both small and large molecule quantitation and characterization. In addition to using a small sample size, this extremely sensitive, versatile instrument will help you save on costs and space, and fully integrates with your SCIEX mass spectrometer of choice.

Bioinert coated YMC Accura BioPro IEX columns provide excellent peak shapes for sensitive compounds, ensuring high recovery from the very first injection.

Bioinert YMC Accura Triart RP and HILIC columns are available for the analysis of critical substances including selected proteins, (oligo)nucleotides and metal-coordinating compounds such as organophosphates.

Markes’ stainless sorbent tubes are available in two sizes: 3.5” x ¼” (industry-standard), and 4.5” x 6mm (DAAMS). Industry-standard tubes are compatible with Markes, PerkinElmer, Shimadzu, Dani, CDS and Gerstel 3.5+ thermal desorption (TD) systems.

Specialized Columns for Mixed Polar and Nonpolar Compounds.

The Ultra line represents Restek’s broadest selection of stationary phases on a single silica support.Made of high-purity, type-B silica that minimizes activity and creates high-density bonding, the Ultra Amino Columns (USP L8) are designed for selective and reliable HPLC applications. Particle size: 3 μm or 5 μm, spherical Pore size: 100 Å Carbon load: 2% End-cap: no pH range: 2.5 to 8 Temperature limit: 80 °C USP phase code…

The Ultra line represents Restek’s broadest selection of stationary phases on a single silica support. Made of high-purity, type-B silica that minimizes activity and creates high-density bonding, the Ultra Cyano Columns (USP L10) are designed for selective and reliable HPLC applications.Particle size: 3 μm or 5 μm, spherical Pore size: 100 Å Carbon load: 8% End-cap: yes pH range: 2.5 to 8 Temperature limit: 80 °C USP phase co…

The Ultra line represents Restek’s broadest selection of stationary phases on a single silica support. Made of high-purity, type-B silica that minimizes activity and creates high-density bonding, Ultra Silica Columns (USP L3) are designed for selective and reliable HPLC applications. Particle size: 3 μm or 5 μm, spherical Pore size: 100 Å End-cap: no pH range: 2.5 to 8 Temperature limit: 80 °C USP phase code: L3 Phase catego…

Viva columns are based on a wide pore material we designed for optimal large-molecule separations.In developing Viva silica, we found that although many commercial wide-pore silicas meet the standard 300 Å mean pore size, most have very broad distributions about this mean, with a significant portion of their pore volume falling below 150 Å.This means a large portion of the surface area is unavailable to larger molecules. Viva…

Use our bulk packing materials to pack your own columns. Our extensive QC program ensures the high quality and reproducibility of these silicas. You can be confident that you are getting consistent, high-quality product when you source your silica from Restek. Use these materials for easy scale-up to preparative chromatography or for packing your own columns. Ultra Bulk Packing Materials Features: Prepare your own columns…

Get more of what you want, and less of what you don't, with Roc™ LC columns from Restek.

Force LC columns are available with Restek's most popular and highly selective Biphenyl and FluoroPhenyl phases, as well as a general-purpose C18.