UHPLC and HPLC Products & Reviews

The 1290 Infinity III Bio Analytical-Scale LC Purification System is an ultrahigh-performance liquid chromatography (UHPLC) system, configurable with a binary or quaternary pump and consisting of biocompatible material for use in biopharma (such as for critical quality attributes).

Agilent NISTmAb is a reference mAb standard that is intended for system suitability testing, establishing method, instrument, or site-to-site variability, and troubleshooting mAb CQA workflows.

Designed to withstand 100% aqueous conditions and increased retention for polar molecules, InfinityLab Poroshell 120 Aq-C18 columns are the modern and reliable choice for HPLC and UHPLC separations. Now master your polar molecules, especially under water.  

100Å pore size, high ligand density;  available in 1.0, 2.0,  3.0, 4.6 and 10 mm ids;  30 - 250 mm lengths. Pursuit columns are ideal for pharmaceutical applications using LC/MS, from analyzing lead compounds and biological samples in drug discovery, to implementing dependable analysis of raw materials and approved drugs in the QC process.  Build on the large 200A pore size silica, high liquid density delivers up to 40% faster…

The 1290 Infinity III Evaporative Light Scattering Detector (ELSD) is ideal for reproducible, sensitve detection of both volatile and nonvolatile compounds that cannot be detected by UV. A unique peltier cooled evaporator coupled with an original gas flow design allow subambient operation down to 10 °C. This delivers maximum sensitivity for compounds with significant volatility below 30 °C.

200A pore size;  available in 3.0 and 4.6  mm ids, and lengths from 50 - 250 mm. Pursuit columns are ideal for pharmaceutical applications using LC/MS, from analyzing lead compounds and biological samples in drug discovery, to implementing dependable analysis of raw materials and approved drugs in the QC process.  Build on the large 200A pore size silica, high liquid density delivers up to 40% faster separations without sacrif…

Agilent Bio-Monolith HPLC columns provide high resolution and rapid separations of antibodies (IgG, IgM), plasmid DNA, viruses, phages and other macro biomolecules. The product family offers strong cation exchange, strong and weak anion exchange, and Protein A phases.

"Extend-C18 columns incorporate a unique patented bidentate silane, combined with a double-endcapping process that protects the silica from dissolution at high pH - up to pH 11.5. Columns are best applied for separations of compounds that are either (1) basic and have little or no retention at low or intermediate pHs, (2) more stable or more soluble at high pH, or (3) basic and show poor peak shape at low or intermediate pH.…

ExionLC AE system provide full integration, control and compatibility with SCIEX mass spectrometers bringing together the speed and precision you expect for a complete solution that meets every challenge your lab faces.

The M5 MicroLC system is a feature rich microflow LC-MS solution meant to simplify both small and large molecule quantitation and characterization. In addition to using a small sample size, this extremely sensitive, versatile instrument will help you save on costs and space, and fully integrates with your SCIEX mass spectrometer of choice.

Bioinert coated YMC Accura BioPro IEX columns provide excellent peak shapes for sensitive compounds, ensuring high recovery from the very first injection.

Bioinert YMC Accura Triart RP and HILIC columns are available for the analysis of critical substances including selected proteins, (oligo)nucleotides and metal-coordinating compounds such as organophosphates.

Run at Higher Flow Rates and Lower Backpressures without Sacrificing Resolution

Bringing You Closer to Universal DetectionWhen carrying out chromatographic runs, do you require any of the following? •Need confidence that you have seen all the peaks in your separation •Require unattended, reproducible operation •Collect fractions that do not have chromophores for UV/Vis triggering With Waters new 2420 ELSD, you’ll get the answers you’re looking for faster. And, the Waters 2420 ELSD is the smallest ELSD on…

eXtended Performance [XP] 2.5 µm Columns are high efficiency, low backpressure HPLC columns that can be easily utilized across all HPLC, UHPLC and UPLC Technology platforms. Low Backpressure. High Throughput. Improved Productivity. • 40% lower backpressure than sub-2-µm UPLC columns • Increase flow rate to increase throughput • Equivalent backpressure and superior performance to core-shell columns • Improve HPLC productivity 2…

The 1.7 µm Ethylene Bridged Hybrid [BEH] particle is one of the key enablers behind UPLC® technology.It is available in three different pore sizes [130Å, 200Å and 300Å] and several bonded phases for reversed-phase and hydrophilic interaction chromatography and is applicable from small molecule to large biopharmaceutical analysis. Due to the intrinsic chemical stability of hybrid particle technology, a wider usable pH range [pH…

The Waters Biopharmaceutical Platform Solution with UNIFI® integrates robust UPLC®/MS characterization technology with the UNIFI Scientific Information System for applications in bioseparations, intact protein mass analysis, peptide mapping and released glycan analysis.This platform unites all aspects of biotherapeutic analyses and workflows, enabling organizations to apply high resolution analytics across the development proc…

The µPorasil/Porasil column brand silica has 125A pore size with 325m2/g surface area. With a range of different particle size offerings, you have the option of scalability for preparative application with µPorasil column as a QC tool.

For high resolution separations of polar compounds

GL Sciences' Bio LC Columns "ProteoSil" are tailored HPLC solutions designed specifically for proteomics and the analysis of bio molecules such as proteins, peptides, and nucleic acids. The packing materials used in these columns are crafted from high-purity silica, offering pore sizes of 100Å, 200Å, and 300Å. They are available in multiple configurations, including reversed phase, HILIC, and size exclusion columns.

High-efficiency separations at any pH

Polymer bulk packing material for anion exchange applications.

The new Anion column line from Hamilton is designed to meet the special requirements of anion analysis.

Hamilton RCX-10 And RCX-30 Columns for the Anion Exchange Separation of Carbohydrates