UHPLC and HPLC Products & Reviews

An ideal solution for trace level PFAS analysis with LC/MS/MS

The 1290 Infinity II Bio Flexible Pump is a UHPLC pump consisting of biocompatible material, designed for use in biopharma and other applications utilizing high-salt and extreme-pH conditions. It offers gradient formation from up to four solvents at pressures up to 1300 bar and flow rates up to 5 mL/min.

InfinityLab solvent glass reservoirs are designed to provide high levels of performance for your LC applications.

The new InfinityLab lamps contain RFID technology for more convenience and ease of use. Agilent lamps are manufactured in an ISO 9001 certified environment and are fully traceable throughout every step of the production process. Each lamp is tested to ensure it meets Agilent performance specifications.

Agilent ZORBAX Eclipse XDB columns – C18, C8, Phenyl and CN – provide four bonded phase choices for method development optimization. These columns provide good peak shape over a wide pH range (2–9) for additional method development flexibility with one family of columns. Eclipse XDB columns can be used for method development at low pH (2–3) and the same column can be used for method development in the mid pH (6–8) region.

Poroshell 120 columns provide rugged, high resolution separations within the pressure range of any mainstream LC system, making the benefits of sub-2 µm performance available with all existing LCs.Poroshell columns can achieve high resolution and high speed separations on current instruments, and higher resolution and speeds on new high-pressure LC and LC/MS systems. Stable to 600 bar, Poroshell 120 are great for fast UHPLC an…

The Nexera XS inert system offers an ideal solution for the separation of biomolecules by combining the elevated pressure tolerance of a UHPLC system with complete inertness of the sample flow path, ensured by the absence of wetted metal surfaces and offering ultra-high resistance to corrosion.

The 1515 Isocratic HPLC Pump is an isocratic pump that offers the same performance as the 1525 Binary HPLC Pump. It features and integrated, high-pressure binary pump with on-board pulse dampening and efficient mixing. Its pulse-free solvent flow with analytical to semi-preparative flow rates are well suited for high sensitivity detectors Designed for use with 2 to 4.6 mm I.D. columns in routine HPLC applications, the pump has…

Protein/Peptide Columns

LC/GC Certified vials are tested by LC/UV for residues of chemicals used in processing and packaging vials. The septa are tested by headspace GC to ensure low levels of low molecular weight polymer. These vials are suited for analyte concentration in the µg/mL concentration; typically detectors like UV and RI.

Most chromatographers have experienced problems retaining and separating polar compounds using conventional reversed-phase chromatography.  These difficult-to-analyze compounds either pass through the column unretained or, if retained at all, co-elute at the beginning of the chromatogram.  Waters AtlantisTM columns are designed for these types of challenging separations and are available in two chemistries: dC18 and HILIC sili…

The most powerful solution to the most critical need in separation science today.

The Waters Alliance 2695 Separations Module is a high performance liquid chromatographic system with a quaternary, low-pressure mixing pump and inline vacuum degassing. Flow rates from 50 uL/min to 5 mL/min can be generated for use with 2.1 mm ID columns and larger. The autosampler has a maximum capacity of 120 vials (12x32, 2-mL) with programmable temperature control from 4 to 40°C. A heated column compartment provides temper…

Making more informed decisions in less time is a universal asset in today's laboratory. Ultra Performance LC™ (UPLC™ ), a new category of separation science pioneered by Waters, will eliminate significant time and cost per sample from your analytical process—while improving the quality of your results. With UPLC technology you benefit from: more data, faster unparalleled sensitivity greater efficiency and confidence in…

Unleash the power of your laboratory's instrumentation. CORTECS® 1.6 µm and 2.7 µm solid-core columns deliver new levels of performance. CORTECS Columns are available in both reversed-phase and HILIC options, giving you the flexibility and power to develop methods for challenging separations even faster. With different particle characteristics and innovative charged surface modifications, CORTECS Columns are suitable for use…

The analysis you’ve always desired for nano- to microscale separations The ACQUITY UPLC M-Class System delivers the most robust, reliable, and highest quality nano- to microscale UPLC separations to every laboratory performing LC/MS analyses. With unprecedented usability, the ACQUITY UPLC M-Class System enables laboratories to succeed in analyzing compounds that are severely limited in amount or availability, even amid a comp…

ACQUITY UPC2 Column Technology for Chiral and Achiral Separations. ACQUITY UPC2 Trefoil™ 2.5 µm Columns are uniquely designed for the ACQUITY UPC2 System. Selectivity and speed for chiral separations Reduce method development time Based on modified polysaccharide-based stationary phases for broad-spectrum chiral selectivity. ACQUITY UPC2 Torus™ Columns simplify the method development process with four completely new…

Empower™ 3 Method Validation Manager (MVM), an option for Empower 3 Chromatography Software, allows you to perform chromatographic method validation, from protocol planning through final reporting, in one application.With Empower 3 MVM you can automatically: Manage method validation workflow in one comprehensive, automated application Clearly display the status of ongoing validation studies – enabling you to see at what…

The Ultra line represents Restek’s broadest selection of stationary phases on a single silica support. Made of high-purity, type-B silica that minimizes activity and creates high-density bonding, these columns are designed for selective and reliable HPLC applications.The Ultra Aqueous C18 HPLC column provides reproducible retention times and can be used with highly aqueous mobile phases, which may eliminate the need for sample…

Properties: • Increased retention for dipolar, unsaturated, or conjugated solutes • Enhanced selectivity when used with methanolic mobile phase • Ideal for increasing sensitivity and selectivity in LC-MS analyses particle size: 3 μm or 5 μm, spherical pore size: 100 Å carbon load: 15% endcap: fully endcapped pH range: 2.5 to 8 temperature limit: 80 °C USP phase: L11 phase category: phenyl ligand type: unique Biphenyl

Developed specifically for using LC coupled with GC-FID to accurately determine hydrocarbons found in mineral oils, which can migrate from packaging into food. • 9-component mix contains non-interfering internal standards as well as both mineral oil saturated hydrocarbon (MOSH) and mineral oil aromatic hydrocarbon (MOAH) markers to correctly cut fractions. • Certified reference material (CRM) manufactured and QC-tested in Re…

A Restek® LC guard cartridge in an EXP® direct connect holder is the ultimate in column protection. To help protect your investment and further extend the life of our already-rugged LC columns, Restek offers the patent-pending guard column hardware developed by Optimize Technologies.Raptor™ EXP® Guard Column Cartridges Features: Free-Turn® architecture lets you change cartridges by hand without breaking inlet/outlet fluid…

The Raptor™ ARC-18 column is made specifically for high-throughput, low–sample prep LC-MS/MS applications. A well-balanced retention profile offers better detection and integration of large, multiclass analyte lists, and steric protection helps this SPP column endure the harsh, low-pH mobile phases needed for mass spec without sacrificing retention or peak quality. Restek chemists became the first to combine the speed of supe…

Diluted and DEA-exempt—no need to purchase costly neat materials or make your own standards. Pair with Restek's THC standards to analyze both neutrals and acids in cannabis products by LC. A must for accurate quantification in medical cannabis potency testing and strain ID. Acetonitrile solvent helps maintain stability by preventing methylation of the carboxylic acid group on the molecule. Certified reference materia…

Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation. Every LC lab has a cache of C18s, but every C18 is not created equal. Because t…