UHPLC and HPLC Products & Reviews

SecurityGuard ULTRA offers a convenient and economical way to extend core-shell, sub-2µm, and other UHPLC column lifetimes SecurityGuard™ ULTRA dramatically extends UHPLC column lifetime and is ideal for virtually any manufacturer's UHPLC, sub-2µm or core-shell columns. SecurityGuard ULTRA protects against the damaging effects of chemical contaminants and microparticulates introduced by the sample, mobile phase or system, whic…

One of the World’s Leading LC Columns

Properties: • Increased retention for dipolar, unsaturated, or conjugated solutes • Enhanced selectivity when used with methanolic mobile phase • Ideal for increasing sensitivity and selectivity in LC-MS analyses particle size: 3 μm or 5 μm, spherical pore size: 100 Å carbon load: 15% endcap: fully endcapped pH range: 2.5 to 8 temperature limit: 80 °C USP phase: L11 phase category: phenyl ligand type: unique Biphenyl

Extends UHPLC, HPLC, SFC, and PREP column lifetime

The EXP® Hand-Tight Nut & Titanium Hybrid Ferrule fitting system is the premier adjustable nut and ferrule compression fitting for extreme high-pressure connections between 1/16" tubing and any 10-32 port. The patent-pending Titanium Hybrid Ferrule integrates the resilience of titanium with the proven sealing ability of PEEK in a superb one-piece design. The Hybrid Ferrule provides a perfect seal with every connection, yet the…

The EXP® Pre-Column Filter is ideal for protecting small-particle UHPLC columns at extreme pressures. Such techniques analyze samples in the most demanding applications, which can decrease the life of these expensive columns. EXP® Pre-Column Filters help extend that life and protect your column investment without sacrificing performance. Free-Turn® architecture allows the user to change cartridges by hand without breaking flui…

OPTI-GUARD® 1mm Guard Columns set the standard for extremely low impact, easy to use pre-column protection. Designed for use with analytical (4.6, 3.0 mm i.d.) and narrow-bore (2.1, 1.0 mm i.d.) columns, the patented floating stem design automatically adjusts to any manufacturer's tube stop depth for a zero-dead-volume connection every time. The best part? It's no larger than a standard fitting. Connecting the OPTI-GUARD® requ…

The OPTI-PAK Trap Columns unique hardware design integrates a PEEK holder with an auto-adjusting stem which provides a fluid interface with any 10-32 standard injector port, and guarantees a zero-dead-volume connection despite variances in tube stop depth. A proprietary method of frit placement allows the packed stem to be positioned directly into the flow path, which eliminates all excess swept volume. Less swept volume trans…

Optimize Technologies, precision machine their components to the most exacting standards in the industry. Everything in the manufacturing process is controlled to ensure the continuing quality that has long been associated with the Optimize name. From the individual matching of check valve ball and seat sets to the proprietary blend of materials in our seals - experience the Optimize advantage.Most instrument manufacturers wil…

Developed specifically for using LC coupled with GC-FID to accurately determine hydrocarbons found in mineral oils, which can migrate from packaging into food. • 9-component mix contains non-interfering internal standards as well as both mineral oil saturated hydrocarbon (MOSH) and mineral oil aromatic hydrocarbon (MOAH) markers to correctly cut fractions. • Certified reference material (CRM) manufactured and QC-tested in Re…

A Restek® LC guard cartridge in an EXP® direct connect holder is the ultimate in column protection. To help protect your investment and further extend the life of our already-rugged LC columns, Restek offers the patent-pending guard column hardware developed by Optimize Technologies.Raptor™ EXP® Guard Column Cartridges Features: Free-Turn® architecture lets you change cartridges by hand without breaking inlet/outlet fluid…

The Raptor™ ARC-18 column is made specifically for high-throughput, low–sample prep LC-MS/MS applications. A well-balanced retention profile offers better detection and integration of large, multiclass analyte lists, and steric protection helps this SPP column endure the harsh, low-pH mobile phases needed for mass spec without sacrificing retention or peak quality. Restek chemists became the first to combine the speed of supe…

Includes 10 ml/min pumps, multi-wavelength (UV/Vis) and conductivity detection, and automated sample injection, for the purification of proteins

Includes 10 ml/min pumps, multi-wavelength (UV/Vis) detection, buffer blending options, for rapid pH scouting during the purification of proteins, peptides, and nucleic acids

Includes 10 ml/min pumps, multi-wavelength (UV/Vis) detection, expanded scouting options, large-sample injection, and column switching of up to 5 columns, for method development

Titan UHPLC columns, based on 1.9 µm totally porous monodisperse silica, outperform other UHPLC columns. These UHPLC columns provide the performance scientists expect (typically > 250,000 N/m), but at a greatly reduced cost. With the narrowest particle size distribution of all available sub-2 µm porous particles, Titan columns are the outcome of the highly efficient patent pending Ecoporous™ silica manufacturing process tha…

Cogent Diamond Hydride HPLC Columns are manufactured with TYPE-C™ silica (silica hydride) and a very small amount of carbon on the surface that adjusts the column hydrophobicity to an important level. This makes these columns have unique separation capabilities for scientists working in LCMS, metabolomics, bioanalytical, amino acids, organic acids, carbohydrates, and very polar small molecules.

Made with a new patent pending, glass manufacturing process, RSA Glass™ vials and inserts have reduced surface activity for basic compounds and sample diluents. This is due to the elimination of virtually all silanols. RSA™ autosampler vials and glass inserts are not manufactured with coatings; but have significantly reduced silanols and surface ions on the glass surface normal produced during the manufacturing process. 

Kromasil Classic is a family of premium silica-based chromatography packings developed for analytical up to process scale applications. Kromasil Classic products are available in three different pore sizes 60Å, 100Å, 300Å, and in particles sizes from 1.8 µm up to 25 µm. Kromasil Classic silica packings are designed to meet the highest demand in HPLC, SFC and SMB from analytical to process scale. The uniqueness of Kromasil Clas…

Diluted and DEA-exempt—no need to purchase costly neat materials or make your own standards. Pair with Restek's THC standards to analyze both neutrals and acids in cannabis products by LC. A must for accurate quantification in medical cannabis potency testing and strain ID. Acetonitrile solvent helps maintain stability by preventing methylation of the carboxylic acid group on the molecule. Certified reference materia…

SecurityGuard Guard Cartridge System Column Protection is designed to fit any manufacturers’ standard HPLC column, making it the ultimate HPLC Guard Column.   SecurityGuard Guard Cartridge System is guaranteed to extend the lifetime of your 2.0 mm, 3.0 mm, 3.2 mm, 4.6 mm, and 7.8mm ID column by capturing sample contaminants that can cause an increase in backpressure and effect baseline noise.     Features:…

DURAN® HPLC Bottle with 4 port GL45 Cap.Safe transfer of HPLC liquids and also used for sterile transfer of liquid media. Complete system including DURAN® Pressure Plus Bottle plus 4 port GL45 PP screw cap. DURAN Pressure Plus bottles are designed and manufactured with a modified geometry for pressure/vacuum resistance from -1 to +1.5 bar in accordance with ISO 4796-1. With pressure load the following apply; thermal shock res…

Ascentis Express RP-Amide HPLC columns are the most recent product additions to the Supelco HPLC product line. Combining an embedded polar group (EPG) stationary phase with the Fused-Core particles, Ascentis Express RP-Amide provides a host of useful benefits to the HPLC chromatographer.   Ascentis Express RP-Amide is a blend of modern phase technology and innovative particle technology. The Fused-Core particle provides…

World-class Small Multi Detection GPC System. A refractive index detector is generally used for GPC analysis of hydrophobic polymers. When trace-level additives that have UV absorption are contained in a polymer, both a UV detector and a photodiode array detector, which offers high-sensitivity detection, are used complementarily.By using the Prominence-i (PDA model), LabSolutions workstation, and LabSolutions GPC software (op…

C18 HPLC column for High Speed and High Resolution Applications. Ascentis® Express C18 is the first choice for starting a new method. Ascentis Express HPLC columns, through the use of Fused-Core® particle technology, can provide you with both the high speed and high efficiencies of sub-2 μm particles at lower system pressure. With identical conditions, the Ascentis Express C18 column performs more than 4X faster tha…