UHPLC and HPLC Products & Reviews

Count on the Waters Arc™ HPLC System for high-efficiency separations and quality data to help meet your regulatory requirements with confidence.  The Arc HPLC system allows you to easily replicate and improve the performance of existing LC methods without compromising data quality.

ACQUITY Premier Columns with MaxPeak High-Performance Surface (HPS) technology reduce analyte/surface interactions.

Solving one of the most challenging chromatographic problems, retaining polar compounds

Along with the reliability, ruggedness, high quality, and configuration flexibility you expect from the ACQUITY™ UPLC™ PLUS Series, the Waters™ ACQUITY Premier System delivers a step change in chromatographic performance, lab efficiency, and risk control.

Accelerate early research, development, & release testing of GTx drug substances and products

ACQUITY UPLC® HSS (High Strength Silica) T3 Columns contain the first and only 100% silica particle designed, tested and intended for use in applications up to 15000 psi/1000 bar. The ACQUITY UPLC® HSS particle is not an HPLC particle. High pore volume HPLC particles do not possess the mechanical stability necessary to withstand the high column packing and operating pressures of UPLC® separations. The first ligand chemistry in…

The Atlantis® T3 HPLC columns set the standard for retention and separation of polar compounds via reversed-phase HPLC. Atlantis® T3 columns are a universal, silica-based, reversed-phase C18 line of HPLC columns that not only retain and separate small, water-soluble polar organic compounds, but also provide superior performance across a wider pH range. Atlantis® columns are the culmination of over 30 years of bonded phase rese…

SunFire™ columns feature excellent low pH stability and improved column lifetime compared to many silica-based HPLC column brands. SunFire columns are packed with state-of-the-art silica and new proprietary C18 and C8 bonding and endcapping for high efficiency, resulting in greater sensitivity.  SunFire columns are manufactured to achieve the highest level of chromatographic consistency column-to-column and batch-to-batch. MS-…

ACQUITY UPLC® BEH C18 and C8 columns were designed to be the universal columns of choice for most UPLC® separations by providing the widest pH range.They incorporate trifunctional ligand bonding chemistries which produce superior low pH stability and ultra-low column bleed. This low pH stability is combined with the high pH stability of the 1.7 µm BEH particle to deliver the widest usable pH operating range. In addition, these…

ACQUITY UPLC® BEH Shield RP18 columns combine Waters patented Shield Technology* with BEH Technology™ by incorporating an embedded carbamate group into the bonded phase ligand.Waters shield ligands consistently demonstrate increased retention of phenolic compounds versus straight chain alkyl columns. The alternate selectivity and excellent peak shape from the embedded polar group ligand, when combined with the wide pH range an…

Column-to-column and batch-to batch reproducibility

Used in a wide range of validated methods

The Breeze™ 2 HPLC System delivers technology and performance in an affordable, compact, and user-friendly system platform. Complete with software, pump, detector and injector, the system comes pre-configured for different levels of HPLC operational needs. From teaching purposes to daily analytical work, the Breeze 2 HPLC System integrates simplicity, sensitivity, accuracy, and reliability. It is ideal for any organization see…

Transform standard procedures into ultimate performance.

The 2489 UV/Visible Detector is a versatile, dual-wavelength absorbance detector for HPLC. This detector offers the high sensitivity required for routine UV-based applications to low-level impurity identification and quantitative analysis. The 2489 UV/Visible detector’s extended linear range of 2.5 AU makes for easy quantitation of both major and minor components in the same run. You can also simultaneously monitor absorbance…

The 2998 Photodiode Array (PDA) Detector offers advanced optical detection for Waters analytical HPLC, preparative HPLC, or LC/MS system solutions. Providing unprecedented trace impurity detection and quantitation, the 2998 PDA Detector’s integrated software and optics innovations deliver high chromatographic and spectral sensitivity. Enhanced software control provides flexibility for simultaneous 2D and 3D operation with eith…

Introducing Waters ACQUITY CSH and XSelect Columns - Powered by CSH Technology Waters patent-pending, Charged Surface Hybrid (CSH™) Technology powers the new Waters ACQUITY CSH and XSelect Column families.CSH Technology columns offer separation scientists a wider range of selectivities and greater performance in LC/MS-compatible mobile phases. Waters CSH Technology empowers UPLCand HPLC systems to provide separations with:Wide…

The Empower Chromatography Data System is Waters’ compliance-ready chromatography data software (CDS) for advanced data acquisition, processing, and reporting that simplifies the management of chromatography test results.

“Allround“ SEC-columns for initial analysis of unknown samples

EcoSEC Elite and EcoSEC HT GPC/SEC Systems enable efficient polymer characterization

TSKgel GPC columns for organic-soluble polymers are packed with spherical particles composed of polystyrene crosslinked with divinylbenzene (PS-DVB)

Ca++Pure-HA is a hydroxyapatite resin used in the chromatographic separation of biomolecules.

TSKgel FcR-IIIA-NPR  affinity columns for direct analysis of mAb activity.

TSKgel Protein A-5PW affinity columns for direct analysis of mAb titer. 

TOYOPEARL NH2-750F offers a high binding capacity across a range of pH values and conductivities