Nuclease Products & Reviews

25

Nuclease

Product Filter

Explore by Field
Enzymes
Nuclease
Refine your selection
Explore by Company

Ratings

Search

Selected Filters:

DNase I (RNase-free)

New England Biolabs Inc.

DNase I, (RNase-free) is an endonuclease that nonspecifically cleaves DNA to release di-, tri- and oligonucleotide products with 5´-phosphorylated and 3´-hydroxylated ends (1,2). DNase I acts on single- and double-stranded DNA, chromatin and RNA:DNA hybrids.

5.0/5.0
|1 Review

Zymolyase

Zymo Research

HIghlights 100 T Equivalent: Prepared from Arthrobacter lutes. Essential enzyme activities are β-1,3-glucanase and β-1,3-glucan laminaripentao-hydrolase. Convenient: Provided lyophilized along with a storage buffer for reconstitution. Efficient Cell Wall Digestion: Supplied storage buffer has been optimized to confer maximum levels of enzymatic activity. Digestion of yeast and fungal cell walls is necessary for…

4.6/5.0
|3 Reviews


Recombinant DNase I (RNase free)

Thermo Fisher Scientific

Thermo Scientific rDNase I is produced through a process that contains no animal by-products. The enzyme is provided free from any detectable RNase activity or animal derivatives. rDNase I has a molecular weight of approximately 30kDa. As an endodeoxyribonuclease, DNase I hydrolyses phosphodiester linkages yielding di-, tri-, and oligonucleotides with a 5' phosphate and a free 3' hydroxyl. DNase I has been shown to act on sing…

5.0/5.0
|1 Review

RNase T1

Properties: Endoribonuclease that preferentially cleaves 3' to G. Guanosine-3'-phosphates and oligonucleotides with guanosine-3'-phosphate terminal groups are the final products. Substrate is single-stranded RNA. Source: Aspergillus oryzae Volume activity: approx. 105 U/ml Unit definition: One unit according to Egami releases a sufficient quantity of acid-soluble oligonucleotides to produce an absorbance increase of 1.0 at 260…

4.7/5.0
|1 Review



Bioprocessing Salt Active Nucleases - High Salt Conditions

ArcticZymes

Salt Active Nuclease High Quality (SAN HQ) is a Bioprocessing Grade nuclease available in GMP grade developed as the most efficient solution for removal of both single and double stranded DNA and RNA at high salt conditions(400–700 mM). It excels in DNA removal for robust viral vectors like Adenovirus and AAV, ensuring superior product purity while improving DSP. Ideal for gene therapy and vaccine manufacturing. Triton free av…

0.0/5.0
|0 Reviews
Request Pricing

Endonucleases DNA-specific

ArcticZymes

Double-Strand Specific dsDNase from ArcticZymes is ideal for removing contaminating DNA from PCR master mixes, preventing false positives in bacterial typing. Recombinantly produced in Pichia pastoris, it cleaves dsDNA with 5000-fold higher specificity than ssDNA. Easily inactivated by moderate heat (65°C), it allows for direct addition of DNA templates post-cleanup, ensuring accurate PCR results.

0.0/5.0
|0 Reviews
Request Pricing

Endonucleases Non-Specific, HL-SAN

ArcticZymes

HL-SAN efficiently removes nucleic acids from buffers in protein purification, excelling in high-salt conditions to reduce aggregation. Ideal for removing nucleic acids from proteins with high DNA/RNA affinity, it performs well during lysis, early purification stages, and high-salt eluates. This cold-adapted enzyme works effectively at ambient temperatures and during overnight digestion at 4°C. Triton free available.

0.0/5.0
|0 Reviews
Request Pricing

Bioprocessing Salt Active Nucleases - Physiological Conditions

ArcticZymes

Nonspecific endonuclease is highly active at physiological conditions (125–200 mM) for DNA removal during protein production, vaccine manufacturing, and viral vector preparation. M-SAN High Quality can be used directly in cell media, which improves efficiency and yield. Designed to replace Benzonase without workflow changes. M-SAN HQ excels in ensuring higher purity and efficiency. High purity (≥ 99%). Compatible with ELISA ki…

0.0/5.0
|0 Reviews
Request Pricing

Endonucleases DNA-specific, HL-dsDNase

ArcticZymes

HL-dsDNase efficiently removes genomic DNA from RNA with minimal impact on RNA quality, reducing 50 ng of gDNA to undetectable levels by qPCR. Easily inactivated by 5-minute incubation at 58°C, it’s ideal for RNA prep, minimizing degradation. It's also effective for removing external DNA from samples before metagenomic sequencing and STR-profiling, for fast, efficient alternative to traditional methods. Triton free available.

0.0/5.0
|0 Reviews
Request Pricing