UHPLC and HPLC Columns Products & Reviews

High Performance Reversed-Phase Columns for the Separation of Small Molecules. The Acclaim® 120 columns are designed for high resolution reversed-phase separations. The very high surface coverage and very low metal content together result in columns with excellent efficiencies. These columns provide exceptional performance for a variety of applications in the pharmaceutical, chemical, environmental, and food separations areas.…

The Acclaim Carbamate column is designed for baseline separation of carbamates (N-methylcarbamate and N-methylcarbamoyloxime pesticides) specified in US EPA Method 531.2. Carbamate pesticides are widely used throughout the world. Drinking water and raw surface water is monitored for the presence of carbamate pesticides and related compounds using an established EPA Method 531.2 that uses HPLC with postcolumn derivatization.…

Ultrahigh-Resolution Separations of OligonucleotidesThe Thermo Scientific™ DNAPac™ PA200 and PA200 RS are strong anion-exchange columns developed to provide unsurpassed high-resolution analysis and purification of synthetic oligonucleotides. Both supports are designed to resolve full length from n–1, n+1, and other failure sequences not possible with other columns. Retention times and selectivity can be controlled by choice of…

MAbPac™ SEC– 1 for Monoclonal Antibody (MAb) Analysis MAbPac™ SEC-1 is a size exclusion chromatography (SEC) column designed for monoclonal antibody (MAb) analysis, including monomers, aggregates, and fragments, under non-denaturing conditions, and in both high- and low-salt mobile phases and volatile eluents.SEC is frequently used because of its simple operating principle and features not found in other sep…

Use the new Thermo Scientific™ MAbPac™ RP columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins. These columns have excellent resolution, long column lifetime, and low carry-over. The surface chemistry, particle size, and pore size, have been optimized to for high resolut…

The Ultra line represents Restek’s broadest selection of stationary phases on a single silica support. Made of high-purity, type-B silica that minimizes activity and creates high-density bonding, these columns are designed for selective and reliable HPLC applications.The Ultra Aqueous C18 HPLC column provides reproducible retention times and can be used with highly aqueous mobile phases, which may eliminate the need for sample…

Properties: • Increased retention for dipolar, unsaturated, or conjugated solutes • Enhanced selectivity when used with methanolic mobile phase • Ideal for increasing sensitivity and selectivity in LC-MS analyses particle size: 3 μm or 5 μm, spherical pore size: 100 Å carbon load: 15% endcap: fully endcapped pH range: 2.5 to 8 temperature limit: 80 °C USP phase: L11 phase category: phenyl ligand type: unique Biphenyl

With Raptor™ LC columns, Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation. SPP core-shell columns commonly employ traditional phe…

The Raptor™ ARC-18 column is made specifically for high-throughput, low–sample prep LC-MS/MS applications. A well-balanced retention profile offers better detection and integration of large, multiclass analyte lists, and steric protection helps this SPP column endure the harsh, low-pH mobile phases needed for mass spec without sacrificing retention or peak quality. Restek chemists became the first to combine the speed of supe…

Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation. Every LC lab has a cache of C18s, but every C18 is not created equal. Because t…